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|Ab urbe condita||2102|
|Balinese saka calendar||1270–1271|
|English Regnal year||22 Edw. 3 – 23 Edw. 3|
|Chinese calendar||戊子年 (Earth Rat)|
4045 or 3985
— to —
己丑年 (Earth Ox)
4046 or 3986
|- Vikram Samvat||1405–1406|
|- Shaka Samvat||1270–1271|
|- Kali Yuga||4449–4450|
|Japanese calendar||Jōwa 5|
|Minguo calendar||563 before ROC|
|Thai solar calendar||1891–1892|
1475 or 1094 or 322
— to —
1476 or 1095 or 323
|Wikimedia Commons has media related to 1349.|
- January 9 – The Jewish population of Basel, Switzerland is rounded up and incinerated, believed by the residents to be the cause of the ongoing Black Death.
- January 22 – An earthquake affects L'Aquila in southern Italy with a maximum Mercalli intensity of X (Extreme), causing severe damage, and leaving 2,000 dead.
- February 14 – Strasbourg massacre: roughly 2,000 Jews are burned to death, believed by the residents to be the cause of the Black Death.
- February 19 – The entire Jewish community in the remote German village of Saulgau was wiped out during the Black Death massacres.
- March 21 – Erfurt massacre: a pogrom in which the Jewish community of Erfurt (Germany) is murdered and expelled, believed by the residents to be the cause of the Black Death.
- March 27 – An earthquake in England strikes Meaux Abbey.
- May – The Black Death ceases in Ireland.
- May 28 – In Breslau, Silesia, 60 Jews are murdered, following a disastrous fire which destroys part of the city.
- August 24 – The Black Death breaks out in Elbing (Poland).
- September 9 – An earthquake in Rome causes extensive damage, including the collapse of the southern exterior facade of the Colosseum.
- October 20 – Pope Clement VI publishes a papal bull that condemns the Flagellants.
- November 8 – Ibn Battuta arrives in Fez, Morocco.
- November 17 – Pope Clement VI annuls the marriage of William Montacute, 2nd Earl of Salisbury, and Joan of Kent, on the grounds of her prior marriage to Thomas Holland, 1st Earl of Kent.
- December 22 – The rise of Alexios III of Trebizond to the throne ends the Trapezuntine Civil Wars.
- April 3 – Eudes IV, Duke of Burgundy (b. 1295)
- May 31 – Thomas Wake, English politician (b. 1297)
- June – Friar John Clyn, Franciscan and Irish chronicler
- June 14 – Günther von Schwarzburg, German king (b. 1304)
- August 26 – Thomas Bradwardine, Archbishop of Canterbury
- September 11 – Bonne of Luxembourg, queen of John II of France (b. 1315)
- October 6 – Joan II of Navarre, daughter of Louis X of France (b. 1311)
- October 25 – James III of Majorca (b. 1315)
- November 18 – Frederick II, Margrave of Meissen (b. 1310)
- date unknown
- probable – William of Ockham, English philosopher (b. 1285)
- "Jewish History Sourcebook: The Black Death and the Jews 1348-1349 CE". New York: Fordham University. Retrieved July 20, 2017.
- "This Month in Jewish History - Shvat". Torahtots.com. Retrieved July 20, 2017.
- Lemaître, Frédéric (September 19, 2011). "Erfurt, ses juifs et l'UNESCO". Le Monde (in French). Paris. Retrieved September 19, 2011.
- "This Month in Jewish History - Sivan". Torahtots.com. Retrieved July 20, 2017.