List of psychedelic drugs

The following is a list of psychedelic drugs of various chemical classes, including both naturally occurring and synthetic compounds. Serotonergic psychedelics are usually considered the "classical" psychedelics[dubious ], whereas the other classes are often seen as having only secondary psychedelic properties; nonetheless all of the compounds listed here are considered psychoactive and hallucinogenic in humans to some degree.

Some of these compounds may be classified differently or under more than one category due to a unique structural classification, multiple mechanisms of action, or the fact that the precise pharmacodynamic actions of the compound are not yet completely understood. Because of the vast amount of possible substitutions and chemical analogs of most psychedelic compounds, the total diversity of chemical compounds which produce psychedelic effects in humans is not fully reflected within this list, leaving room for many that have not yet been sufficiently investigated and others that have not yet been discovered.

Naturally occurring compounds are marked with a †.

Serotonergic psychedelics (serotonin 5-HT2A receptor agonists)Edit

Empathogens/entactogens (serotonin (5-HT) releasing agents)Edit

Cannabinoids (CB-1 cannabinoid receptor ligands)Edit


See alsoEdit


  1. ^ Pertwee, R G (April 2006). "The pharmacology of cannabinoid receptors and their ligands: an overview". International Journal of Obesity. 30 (S1): S13–S18. doi:10.1038/sj.ijo.0803272. ISSN 0307-0565. PMID 16570099.
  2. ^ Cannabis and cannabinoids : pharmacology, toxicology, and therapeutic potential. Grotenhermen, Franjo., Russo, Ethan. New York: Haworth Integrative Healing Press. 2002. ISBN 9781136614941. OCLC 606854125.{{cite book}}: CS1 maint: others (link)
  3. ^ Huestis, M. A. (2005), "Pharmacokinetics and Metabolism of the Plant Cannabinoids, Δ9-Tetrahydrocannibinol, Cannabidiol and Cannabinol", in Pertwee, Roger G. (ed.), Cannabinoids, Handbook of Experimental Pharmacology, vol. 168, Springer-Verlag, pp. 657–690, doi:10.1007/3-540-26573-2_23, ISBN 9783540225652
  4. ^ Laprairie, R B; Bagher, A M; Kelly, M E M; Denovan‐Wright, E M (October 2015). "Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor". British Journal of Pharmacology. 172 (20): 4790–4805. doi:10.1111/bph.13250. ISSN 0007-1188. PMC 4621983. PMID 26218440.