11-Hydroxy-Δ9-tetrahydrocannabinol (11-OH-THC), usually referred to as 11-hydroxy-THC, is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after decarboxylated cannabis is consumed.
|Chemical and physical data|
|Molar mass||330.461 g/mol g·mol−1|
|3D model (JSmol)|
|(what is this?)|
Fresh cannabis contains tetrahydrocannabinolic acid (THCA), which is converted into THC after heating and then metabolized by the body into 11-hydroxy-THC and then into 11-nor-9-carboxy-THC; both compounds can be glucuronidated and mainly excreted into urine. Both compounds, along with THC, are assayed in blood tests.
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- Huestis, MA (2005). "Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol". Handbook of experimental pharmacology (168): 657–90. doi:10.1007/3-540-26573-2_23. PMID 16596792.