User:Y-S.Ko/Wikipedia course/Medical/Respiratory

Preclinical

Trachea	Tracheal rings Annular ligaments Carina
Bronchi	Main left right Secondary eparterial Tertiary

Lungs

General	Landmarks Base Apex Root Hilum Fissures Horizontal Oblique Superior lobe Lingula of left lung Middle lobe of right lung Inferior lobe
BP segment	Bronchiole: Conducting zone (Terminal bronchiole) Respiratory zone (Respiratory bronchiole Alveolar duct Alveolus Blood-air barrier)
Cells	Alveolar cells Type I Type II Club cell Goblet cell

v t e Respiratory physiology
Respiration	breath inhalation exhalation obligate nasal breathing respiratory rate respirometer pulmonary surfactant compliance elastic recoil hysteresivity airway resistance bronchial hyperresponsiveness constriction dilatation mechanical ventilation
Control	pons pneumotaxic center apneustic center medulla dorsal respiratory group ventral respiratory group chemoreceptors central peripheral pulmonary stretch receptors Hering–Breuer reflex
Lung volumes	VC FRC Vt dead space CC PEF calculations respiratory minute volume FEV1/FVC ratio Lung function tests spirometry body plethysmography peak flow meter nitrogen washout
Circulation	pulmonary circulation hypoxic pulmonary vasoconstriction pulmonary shunt
Interactions	ventilation (V) Perfusion (Q) Ventilation/perfusion ratio V/Q scan zones of the lung gas exchange pulmonary gas pressures alveolar gas equation alveolar–arterial gradient hemoglobin oxygen–hemoglobin dissociation curve (Oxygen saturation 2,3-BPG Bohr effect Haldane effect) carbonic anhydrase (chloride shift) oxyhemoglobin respiratory quotient arterial blood gas diffusion capacity (DLCO)
Insufficiency	high altitude death zone oxygen toxicity hypoxia

Clinical

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Signs and symptoms relating to the respiratory system

Auscultation

Stethoscope
Respiratory sounds
- Stridor
- Wheeze
- Crackles
- Rhonchi
- Stertor
- Squawk
- Pleural friction rub
- Fremitus
- Bronchophony
- Death rattle
Elicited findings

Breathing

Rate	Apnea Prematurity Dyspnea Hyperventilation Hypoventilation Hyperpnea Tachypnea Hypopnea Bradypnea
Pattern	Agonal respiration Biot's respiration Cheyne–Stokes respiration Kussmaul breathing Ataxic respiration
Other	Respiratory distress Respiratory arrest Orthopnea/Platypnea Trepopnea Aerophagia Asphyxia Breath holding Mouth breathing Snoring

Other

Tests and procedures involving the respiratory system

Surgery

Upper RT	nose Rhinoplasty Septoplasty Somnoplasty Alarplasty Rhinectomy Rhinomanometry Acoustic rhinometry sinus Sinusotomy larynx Laryngoscopy Laryngectomy Laryngotomy Thyrotomy Laryngotracheal reconstruction
Lower RT	trachea Cricothyrotomy Tracheoesophageal puncture Tracheotomy bronchus Bronchoscopy lung Pneumonectomy Lobectomy Wedge resection Transplantation Decortication Heart–lung transplant
Chest wall, pleura, mediastinum, and diaphragm	pleura/pleural cavity Thoracentesis Pleurodesis Thoracoscopy Thoracotomy Chest tube mediastinum Mediastinoscopy Nuss procedure

Tests

Medical imaging	Bronchography CT pulmonary angiogram High-resolution computed tomography Spiral CT Ventilation/perfusion scan
Clinical prediction rule	Pneumonia severity index CURB-65
Lung function test	Body plethysmography Spirometry Bronchial challenge test Capnography Diffusion capacity Impulse oscillometry
Cytology	Bronchoalveolar lavage Nasopharyngeal swab Sputum culture
Other	Blood gas test

Other procedures

Oxygen therapy	Intubation Surgical airway management Mechanical ventilation Negative pressure ventilator Positive pressure ventilation
Respiratory therapy	Artificial respiration CPR Hyperbaric medicine Decompression chamber Heliox Nebulizer Postural drainage Hyperinflation therapy Pulmonary hygiene Pulmonary rehabilitation

Diseases of the respiratory system

Upper RT
(including URTIs,
common cold)

Head	sinuses Sinusitis nose Rhinitis Vasomotor rhinitis Atrophic rhinitis Hay fever Nasal polyp Rhinorrhea nasal septum Nasal septum deviation Nasal septum perforation Nasal septal hematoma tonsil Tonsillitis Adenoid hypertrophy Peritonsillar abscess
Neck	pharynx Pharyngitis Strep throat Laryngopharyngeal reflux (LPR) Retropharyngeal abscess larynx Croup Laryngomalacia Laryngeal cyst Laryngitis Laryngopharyngeal reflux (LPR) Laryngospasm vocal cords Laryngopharyngeal reflux (LPR) Vocal fold nodule Vocal fold paresis Vocal cord dysfunction epiglottis Epiglottitis trachea Tracheitis Laryngotracheal stenosis

Lower RT/
lung disease
(including LRTIs)

Bronchial/
obstructive

acute: Acute bronchitis

chronic

COPD

Chronic bronchitis

Acute exacerbation of COPD)

Asthma (Status asthmaticus

unspecified

Bronchiolitis obliterans

Diffuse panbronchiolitis

Interstitial/
restrictive
(fibrosis)

External agents/ occupational lung disease	Pneumoconiosis Aluminosis Asbestosis Baritosis Bauxite fibrosis Berylliosis Caplan's syndrome Chalicosis Coalworker's pneumoconiosis Siderosis Silicosis Talcosis Byssinosis Hypersensitivity pneumonitis Bagassosis Bird fancier's lung Farmer's lung Lycoperdonosis
Other	ARDS Combined pulmonary fibrosis and emphysema Pulmonary edema Löffler's syndrome/Eosinophilic pneumonia Respiratory hypersensitivity Allergic bronchopulmonary aspergillosis Hamman–Rich syndrome Idiopathic pulmonary fibrosis Sarcoidosis Vaping-associated pulmonary injury

Obstructive /
Restrictive

Pneumonia/
pneumonitis

By pathogen	Viral Bacterial Pneumococcal Klebsiella Atypical bacterial Mycoplasma Legionnaires' disease Chlamydiae Fungal Pneumocystis Parasitic noninfectious Chemical/Mendelson's syndrome Aspiration/Lipid
By vector/route	Community-acquired Healthcare-associated Hospital-acquired
By distribution	Broncho- Lobar
IIP	UIP DIP BOOP-COP NSIP RB

Other

Atelectasis
circulatory
- Pulmonary hypertension
- Pulmonary embolism
Lung abscess

Pleural cavity/
mediastinum

Pleural disease	Pleuritis/pleurisy Pneumothorax/Hemopneumothorax Pleural effusion Hemothorax Hydrothorax Chylothorax Empyema/pyothorax Malignant Fibrothorax
Mediastinal disease	Mediastinitis Mediastinal emphysema

Other/general

Drugs

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Decongestants and other nasal preparations (R01)

Topical

Sympathomimetics, plain	Cyclopentamine Ephedrine Epinephrine Fenoxazoline Levomethamphetamine Metizoline Naphazoline Oxymetazoline Phenylephrine Propylhexedrine Tetryzoline Tramazoline Tuaminoheptane Tymazoline Xylometazoline
Antiallergic agents, excluding corticosteroids	Spaglumic acid histamine antagonists (Levocabastine Antazoline Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid Nedocromil Azelastine Olopatadine Lodoxamide)
Corticosteroids	Beclometasone dipropionate Betamethasone^# Budesonide Ciclesonide Dexamethasone Flunisolide Fluticasone (Fluticasone furoate, Fluticasone propionate) Mometasone furoate Prednisolone^# Tixocortol Triamcinolone Triamcinolone acetonide
Other nasal preparations	Cafaminol Calcium hexamine thiocyanate Eucalyptus oil Framycetin Hexamidine Hyaluronan Ipratropium bromide Mupirocin Retinol Ritiometan Saline water
Combination products	Olopatadine/mometasone

Systemic use:
Sympathomimetics

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

v t e Throat preparations (R02)
Antiseptics	Acriflavinium chloride Ambazone Amylmetacresol Benzalkonium Benzethonium Cetrimonium (bromide/chloride) Cetylpyridinium Chlorhexidine Chlorquinaldol Dequalinium Dichlorobenzyl alcohol Hexamidine Hexetidine Hexylresorcinol Myristyl-benzalkonium Oxyquinoline Phenol Povidone-iodine
Antibiotics	Bacitracin Fusafungine Gramicidin Neomycin Tyrothricin
Local anesthetics	Benzocaine Cocaine Dyclonine Lidocaine
Other	Flurbiprofen

Drugs for obstructive airway diseases: asthma/COPD (R03)

Adrenergics, inhalants

Short-acting β₂ agonists	Bitolterol Carbuterol Fenoterol Isoetarine Pirbuterol Procaterol Reproterol Rimiterol Salbutamol (albuterol)^#/Levosalbutamol (levalbuterol) Terbutaline Tulobuterol
Long-acting β₂ agonists	Bambuterol Clenbuterol Formoterol/Arformoterol Salmeterol Salmefamol
Ultra-long-acting β₂ agonists	Abediterol Carmoterol Indacaterol Olodaterol Vilanterol
Other	Epinephrine^# Hexoprenaline Isoprenaline (isoproterenol) Orciprenaline (metaproterenol)

Glucocorticoids

Anticholinergics/
muscarinic antagonist

Mast cell stabilizers

Xanthines

Eicosanoid inhibition

Leukotriene antagonists	Montelukast Pranlukast Zafirlukast
Arachidonate 5-lipoxygenase inhibitors	Zileuton
Thromboxane receptor antagonists	Ramatroban Seratrodast
Non-xanthine PDE4 inhibitors	Ibudilast Roflumilast

Others/unknown

Combination products

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Cough and cold preparations (R05)

Expectorants

Mucolytics

Cough suppressants

Opium alkaloids,
opioids,
and derivatives

Acetyldihydrocodeine
Benzylmorphine
Butorphanol
Codeine^# (+guaifenesin)
Dextromethorphan
Dihydrocodeine
Dimemorfan
Ethylmorphine
Heroin
Hydrocodone (+guaifenesin, +homatropine)
Hydromorphone
Laudanum
Levomethadone
Levopropoxyphene
Methadone
Nicocodeine
Nicodicodeine
Normethadone
Noscapine
Pholcodine
Thebacon

Other

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

v t e Antihistamines (R06)
Benzimidazoles (*)	Astemizole Azelastine Bilastine Emedastine Mizolastine Talastine
Diarylmethanes	Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine) Carbinoxamine Chlorphenoxamine Clemastine Diphenhydramine (+naproxen) Diphenylpyraline Doxylamine Ebastine Orphenadrine Diphenylmethanolpiperidines: Fexofenadine Terfenadine Diphenylmethylpiperazines: Buclizine Cetirizine Levocetirizine Chlorcyclizine Cinnarizine Cyclizine Etodroxizine Hydroxyzine Meclizine Oxatomide Phenylpyridinylpropanamines: Brompheniramine Chlorphenamine Dexbrompheniramine (+pseudoephedrine) Dexchlorpheniramine (+betamethasone) Pheniramine Others: Acrivastine Bamipine Dimetindene Phenyltoloxamine Pyrrobutamine Quifenadine Triprolidine
Ethylenediamines	Antazoline Chloropyramine Histapyrrodine Mepyramine (pyrilamine) Methapyrilene Phenbenzamine Thenalidine Tripelennamine (pyribenzamine)
Tricyclics	Dibenzocycloheptenes: Antidepressants (e.g., amitriptyline) Azatadine Cyproheptadine Deptropine Desloratadine Ketotifen Loratadine Rupatadine Phenothiazines: Alimemazine Fenethazine Hydroxyethylpromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine Others: Antidepressants (e.g., doxepin, mirtazapine, trimipramine) Epinastine Latrepirdine Mebhydrolin Olopatadine Perlapine Phenindamine Pimethixene
Others	Phenylpiperazines: Antidepressants (e.g., trazodone) Phenbenzamine
For topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Doxepin Isothipendyl Mepyramine (pyrilamine) Promethazine

v t e Other respiratory system products (R07)
Lung surfactants	Colfosceril palmitate Dipalmitoylphosphatidylcholine
Respiratory stimulants	Almitrine Amiphenazole Bemegride Dimefline Doxapram Etamivan GAL-021 Mepixanox Nikethamide Pentetrazol Prethcamide
5-HT4 receptor agonists	BIMU-8 Zacopride
Other agents for treating respiratory depression	Ivacaftor (+ lumacaftor, + tezacaftor, + elexacaftor/tezacaftor) Nitric oxide BW373U86 CX-546 CX-717