Oro Temp

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Happy editing! --William Graham ^talk 02:20, 25 August 2022 (UTC)

Your submission at Articles for creation: Monoamine activity enhancer has been accepted

Monoamine activity enhancer, which you submitted to Articles for creation, has been created.

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Graeme Bartlett (talk) 20:04, 12 February 2023 (UTC)

Your submission at Articles for creation: MZ-5-156 (February 19)

Your recent article submission to Articles for Creation has been reviewed! Unfortunately, it has not been accepted at this time. The reason left by Praseodymium-141 was: Please check the submission for any additional comments left by the reviewer. You are encouraged to edit the submission to address the issues raised and resubmit after they have been resolved.

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¹⁴¹Pr {^contribs/_{Best page}} 14:50, 19 February 2023 (UTC)

Hello, Oro Temp! Having an article draft declined at Articles for Creation can be disappointing. If you are wondering why your article submission was declined, please post a question at the Articles for creation help desk. If you have any other questions about your editing experience, we'd love to help you at the Teahouse, a friendly space on Wikipedia where experienced editors lend a hand to help new editors like yourself! See you there! 141Pr {contribs/Best page} 14:50, 19 February 2023 (UTC)

Which of the general reasons listed applies to the article? So that I may improve it for future submission Oro Temp (talk) 20:13, 19 February 2023 (UTC)

Your submission at Articles for creation: TAK-653 has been accepted

TAK-653, which you submitted to Articles for creation, has been created.

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¹⁴¹Pr {^contribs/_{Best page}} 16:32, 26 February 2023 (UTC)

CS1 error on Space medicine

Hello, I'm Qwerfjkl (bot). I have automatically detected that this edit performed by you, on the page Space medicine, may have introduced referencing errors. They are as follows:

• A "bare URL and missing title" error. References show this error when they do not have a title. Please edit the article to add the appropriate title parameter to the reference. (Fix | Ask for help)

Please check this page and fix the errors highlighted. If you think this is a false positive, you can report it to my operator. Thanks, Qwerfjkl (bot) (talk) 23:52, 17 July 2023 (UTC)

Concern regarding Draft:RA03546849

Hello, Oro Temp. This is a bot-delivered message letting you know that Draft:RA03546849, a page you created, has not been edited in at least 5 months. Drafts that have not been edited for six months may be deleted, so if you wish to retain the page, please edit it again or request that it be moved to your userspace.

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Thank you for your submission to Wikipedia. FireflyBot (talk) 02:01, 3 September 2023 (UTC)

Your submission at Articles for creation: RA03546849 (September 4)

Your recent article submission to Articles for Creation has been reviewed. Unfortunately, it has not been accepted at this time. The reason left by Dan arndt was:  The comment the reviewer left was: Please check the submission for any additional comments left by the reviewer. You are encouraged to edit the submission to address the issues raised and resubmit after they have been resolved.

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Dan arndt (talk) 09:06, 4 September 2023 (UTC)

Concern regarding Draft:Pinealon

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Thank you for your submission to Wikipedia. FireflyBot (talk) 19:36, 17 September 2023 (UTC)

Your submission at Articles for creation: Pinealon has been accepted

Pinealon, which you submitted to Articles for creation, has been created.

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Devonian Wombat (talk) 11:39, 26 September 2023 (UTC)

September 2023

Please do not insert fringe or undue weight content into articles, as you did to Withania somnifera. An article should not give undue weight to any aspects of the subject but should strive to treat each aspect with a weight appropriate to its significance to the subject. Please use the article's talk page to discuss the material and its appropriate weight within the article. Anything from Ayurveda is quackery nonsense. Please keep this out of the encyclopedia. Zefr (talk) 21:46, 30 September 2023 (UTC)

I am shocked to hear that your reasoning here is "Anything from Ayurveda is quackery nonsense.". Ayurveda was not cited as a source, clinical data was. Plants and the therapeutic effects they may produce do not have cultural allegiances. This plant happens to possess well documented stress and anxiety reducing effects in humans rooted in evidence-based medicine.

Substantiate your claim with evidence to the contrary, or rescind your stance. What you have presented is a gross generalisation with culturally elitist undertones.

I urge you to familiarize yourself with the research which overwhelmingly supports the validity of Ashwaghanda's cortisol, stress, and anxiety reducing effects in humans:

Ashwaghanda reduces ratings of stress in humans: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/

https://pubmed.ncbi.nlm.nih.gov/34858513/

https://pubmed.ncbi.nlm.nih.gov/31517876/

Ashwaghanda reduces cortisol levels in humans:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750292/

https://www.sciencedirect.com/science/article/pii/S0975947621001558

Ashwaghanda reduces anxiety ratings in humans:

https://pubmed.ncbi.nlm.nih.gov/36017529/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/

https://www.sciencedirect.com/science/article/pii/S0975947621001558

Many of these studies and other research papers were cited in the original review sourced in my edit. I avoided individually citing each source to avoid excessive citations, but I have now done so. Although the citations are effectively the same, they no longer contain the prohibited "Ayurveda" in their titles. Oro Temp (talk) 18:20, 1 October 2023 (UTC)

All these citations are preliminary (primary) research, unconfirmed by sufficient research and not acknowledged in any high-quality review published in a reputable clinical journal or medical textbook.

Evidently, you have not read WP:MEDRS. There are no clinical organizations, no national regulatory agencies, and no MEDRS reviews that support the use of W. somnifera for any of these effects. Wikipedia is not a journal for recording vague primary studies, WP:NOTJOURNAL #6-8, but rather is an encyclopedia for stating the best-supported facts for medical content. See also WP:WHYMEDRS. Zefr (talk) 19:16, 1 October 2023 (UTC)

I agree with the notion that primary sources should not be presented when secondary sources are available. This is why I found it odd when my original edit, which cited a systematic review, was reverted because "Anything from Ayurveda is quackery nonsense." . According to the MEDRS, this does not correspond to the guideline of "Respecting secondary sources". If you wish to cite the impact factor in your response, please note that there are several reviews from journals with respectable impact factors which in any other circumstance abide by MEDRS:

Journal of Functional Morphology: 2.67

Phytotherapy Research: 6.338

PLOS ONE: 3.752

(the reviews are linked)

The findings of these secondary sources clearly state that there is moderate quality evidence with low-moderate risk of bias supporting Ashwagandha's efficacy in reducing perceived stress markers, cortisol, and anxiety alongside improvements physical performance. This research can easily be cited within the article with an added caveat stating that "the evidence is of moderate quality and further research is needed to confirm these effects" as is done in every other medical Wikipedia page. Nobody is proposing that the page be a storefront for Ashwagandha supplements in the interest of big Ayurveda.

The evidence supporting Ashwagandha's effects is past the point at which it should be gatekept from a Wikipedia article provided proper disclaimer is present. "Wikipedia is an encyclopedia for stating the best-supported facts", what I and many others have presented ARE "the best-supported facts".

I will echo some points fellow editors have made on the talk page of Withania somnifera:

"I would like to know exactly which sources are considered to be "quackery" associated with "Ayurvedic journals". This herb has been extensively researched, and it is a disservice to the community not to publish some of this research. While it is appropriate to include the limitations of this research, it is not appropriate to refuse to allow legitimate secondary sources and the conclusions of their authors."

"'Conclusive evidence' is evidence which cannot be contradicted by other evidence. Given that scientific progress in empirical fields relies on falsifiability (read Karl Popper), there will NEVER be conclusive evidence on this topic... We must instead make an assessment on whether there is a preponderance of evidence in favour of a specific conclusion." Oro Temp (talk) 22:43, 1 October 2023 (UTC)

Please present here or the article talk page what you feel are WP:MEDRS-compliant reviews, national clinical guidelines or government sources showing substantial scientific consensus in support of any of your claims above, WP:MEDSCI and WP:MEDASSESS. Zefr (talk) 23:20, 1 October 2023 (UTC)

Your submission at Articles for creation: Esmodafinil has been accepted

Esmodafinil, which you submitted to Articles for creation, has been created.

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Thanks again, and happy editing!

Troutfarm27 ^(Talk) 16:55, 31 October 2023 (UTC)

Your submission at Articles for creation: HGH Fragment 176-191 has been accepted

HGH Fragment 176-191, which you submitted to Articles for creation, has been created.

Congratulations, and thank you for helping expand the scope of Wikipedia! We hope you will continue making quality contributions.

Since you have made at least 10 edits over more than four days, you can now create articles yourself without posting a request. However, you may continue submitting work to Articles for creation if you prefer.

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WikiOriginal-9 (talk) 19:26, 4 November 2023 (UTC)

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Concern regarding Draft:MZ-5-156

Hello, Oro Temp. This is a bot-delivered message letting you know that Draft:MZ-5-156, a page you created, has not been edited in at least 5 months. Drafts that have not been edited for six months may be deleted, so if you wish to retain the page, please edit it again or request that it be moved to your userspace.

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Thank you for your submission to Wikipedia. FireflyBot (talk) 02:05, 2 December 2023 (UTC)

Your submission at Articles for creation: A0D9604 has been accepted

A0D9604, which you submitted to Articles for creation, has been created.

Congratulations, and thank you for helping expand the scope of Wikipedia! We hope you will continue making quality contributions.

The article has been assessed as Stub-Class, which is recorded on its talk page. It is commonplace for new articles to start out as stubs and then attain higher grades as they develop over time. You may like to take a look at the grading scheme to see how you can improve the article.

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Thanks again, and happy editing!

Graeme Bartlett (talk) 22:27, 25 December 2023 (UTC)

HGH Fragment 176–191 vs AOD9604

There is indeed a mess here! I'm trying to clarify the identity of each of these. Cited ref PMC 9249349 says "A C-terminal hGH fragment 176–191 with a tyrosine to phenylalanine substitution at the last position has been reported to enhance lipid breakdown and fat utilization in mice" but cited ref PMC 11713213 says "AOD9604, a synthetic fragment of hGH consisting of the amino acid residues 177–191 with the addition of a tyrosine residue to the N-terminus". So I'm confused. Which one is Phe¹⁷⁶ and which one is Tyr¹⁷⁶? DMacks (talk) 09:34, 26 December 2023 (UTC)

I got info for AOD9604 from Pubchem. Suggests that the fragment would be H-Tyr-Leu-Arg-Ile-Val-Gln-Cys(1)-Arg-Ser-Val-Glu-Gly-Ser-Cys(1)-Gly-Tyr-OH. But I see no reference on this. Graeme Bartlett (talk) 10:34, 26 December 2023 (UTC)

Concern regarding Draft:Desmethylzopiclone

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Thank you for your submission to Wikipedia. FireflyBot (talk) 22:05, 31 March 2024 (UTC)

Your submission at Articles for creation: Desmethylzopiclone (April 14)

Your recent article submission to Articles for Creation has been reviewed. Unfortunately, it has not been accepted at this time. The reason left by Urban Versis 32 was: Please check the submission for any additional comments left by the reviewer. You are encouraged to edit the submission to address the issues raised and resubmit after they have been resolved.

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Urban Versis 32^KB ⚡ ^{(talk / contribs)} 21:17, 14 April 2024 (UTC)