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The 2018 Kivu Ebola outbreak[note 1] began on 1 August 2018, when it was confirmed that four cases had tested positive for Ebola virus in the eastern region of Kivu in the Democratic Republic of the Congo (DRC).[3][4][5] The Kivu outbreak included Ituri Province, after the first case was confirmed on 13 August.[2] This outbreak started just days after the end of the outbreak in Équateur province.[6][7]

2018 Kivu Ebola outbreak
Initial case: 1 August 2018
North Kivu and Ituri province, DRC
Location of North Kivu and Ituri province in the Democratic Republic of the Congo
Map showing the location the Democratic Republic of the Congo in Africa
Location of the Democratic Republic of the Congo in Africa. As of 17 April 2019
Confirmed cases1,224[1]
Probable cases66[1]
Suspected cases251[1]
Total cases1,541[1]
Deaths833[1]

The affected province and general area are currently undergoing a military conflict, which is hindering treatment and prevention efforts. The World Health Organization's Deputy Director-General for Emergency Preparedness and Response has described the combination of military conflict and civilian distress as a potential "perfect storm" that could lead to a rapid worsening of the outbreak.[8][9] Health workers also have to deal with fake news and other misinformation spread by opposing politicians.[10] Due to the deteriorating situation in North Kivu and surrounding areas the World Health Organization raised the risk assessment at the national and regional level from "high" to "very high" on 27 September 2018;[11] as of April 2019, the outbreak is not considered to be a Public Health Emergency of International Concern.[12]

On 3 October, the United Nations Security Council stressed that all armed hostility should come to a stop in the DRC, to better fight the ongoing Ebola virus disease (EVD) outbreak.[13] For the week ending 14 October, DRC indicated 33 cases of EVD were identified, of which 24 died, in one week.[14] On 9 November, at 319 probable and confirmed cases (not counting suspected cases) the 2018 North Kivu and Ituri province Ebola virus outbreak became the biggest in the DRC's history.[15][16]

By 30 November, the 2018 Kivu Ebola outbreak had become the second biggest EVD outbreak in recorded history,[17][18][19] behind only the 2013–2016 West Africa epidemic. On 13 February 2019, the total cases (confirmed, probable and suspected) equalled 1,000 individuals in the Democratic Republic of the Congo; it is a cases count ( ≥ 1,000) for a single country not seen since the 2013 West Africa Epidemic, in Liberia, Guinea and Sierra Leone.[20][21]

Contents

EpidemiologyEdit

First cases and transmissionEdit

On 1 August 2018, the North Kivu health division notified Congo's health ministry of 26 cases of hemorrhagic fever, including 20 deaths. Four of six samples were sent for analysis to the National Institute of Biological Research in Kinshasa. Four of the six came back positive for Ebola and an outbreak was declared on that date.[22][23] The index case is believed to have been the death and unsafe burial of a 65-year-old woman on July 25 in the town of Mangina; soon afterwards seven members of her immediate family died.[24]

By 3 August, the virus had developed in multiple locations; cases were reported in five health zones – Beni, Butembo, Oicha, Musienene and Mabalako – in North Kivu province and additionally, Mandima and Mambasa in Ituri Province.[25] However, one month later there had been confirmed cases only in the Mabalako, Mandima, Beni and Oicha health zones. The five suspected cases in the Mambasa Health Zone proved not to be EVD; it was not possible to confirm the one probable case in the Musienene Health Zone and the two probable cases in the Butembo health zone. No new cases had been recorded in any of those health zones. The first confirmed case in Butembo was announced on 4 September, the same day that it was announced that one of the cases registered at Beni had actually come from the Kalunguta Health Zone.[26]

The DRC Ministry of Public Health confirmed that the new Ebola outbreak is caused by the Zaire ebolavirus species. This is the same strain that was involved in the early 2018 outbreak in western DRC.[27] Health authorities in the DRC confirmed they would use the ZEBOV vaccine once again.[27]

On 1 August, just after the Ebola epidemic had been declared, Doctors Without Borders/Médecins Sans Frontières (MSF) arrived in Mangina, the epicenter of the outbreak to mount a response against the outbreak.[28] On 2 August, Oxfam indicated it would be taking part in the response to this latest outbreak in the DRC.[29] On 4 August, the World Health Organization (WHO) indicated that the current situation in the DRC, due to several factors, warranted a "high risk assessment" at the national and regional level for public health.[30]

 
Figure 1. 2018 Kivu Democratic Republic of the Congo Ebola virus outbreak (total cases-death as of 7 April.[31])
(note-above graph omits 9-21, 11/11, 12/10 & 1/11 due to n/a)


In November it was reported that the EVD outbreak ran across two provinces (and 14 health zones). The table below reflects cases that were not able to have a laboratory test sample prior to burial as probable cases.[32] By 23 December the EVD outbreak had spread to more health zones, and at that time 18 such areas had been affected.[33] The current population in DRC is more than 84,000,000 people.[34]

Table 1.Timeline reported cases[35]
Date Cases #  Deaths CFR Contacts Sources
Confirmed Probable Suspected Totals
 2018-08-01 4 22 0 26 20 - - [36]
2018-08-03 13 30 33 76 33 76.7% 879 [37][38]
2018-08-05 16 27 31 74 34 79%    966 [39][40]
2018-08-10 25 27 48 100 39 75%    953 [41]
2018-08-12 30 27 58 115 41 - 997 [42]
2018-08-17 64 27 12 103 50 55.6% 1,609 [43]
2018-08-20 75 27 9 111 59 - 2,408 [44]
2018-08-24 83 28 6 117 72 65%    3,421 [45]
2018-08-26 83 28 10 121 75 67.6% 2,445 [46]
2018-08-31 90 30 8 128 78 65%    2,462 [47]
2018-09-02 91 31 9 131 82 - 2,512 [48]
2018-09-07 100 31 14 145 89 68%    2,426 [49]
2018-09-09 101 31 9 141 91 - 2,265 [50][51]
2018-09-14 106 31 17 154 92 67.2% 1,751 [52]
2018-09-16 111 31 7 149 97 - 2,173 [53][54]
2018-09-21 116 31 n/a 147 99 67.3% 1,641 [55]
2018-09-23 119 31 9 159 100 67%    1,836 [56]
2018-09-28 126 31 23 180 102 65%    1,410 [57]
2018-10-02 130 32 17 179 106 65.4% 1,463 [58]
2018-10-05 142 35 11 188 113 63.8% 2,045 [59]
2018-10-07 146 35 21 202 115 63.5% 2,115 [60]
2018-10-12 176 35 32 243 135 64%    2,663 [61]
2018-10-15 181 35 32 248 139 64%    4,707 [62]
2018-10-19 202 35 33 270 153 65%    5,518 [63]
2018-10-21 203 35 14 252 155 65%    5,341 [64]
2018-10-26 232 35 43 310 170 64%    6,026 [65]
2018-10-28 239 35 32 306 174 63.5% 5,991 [66]
2018-11-02 263 35 70 368 186 62.4% 5,036 [67]
2018-11-04 265 35 61 361 186 62%    4,971 [68]
2018-11-09 294 35 60 389 205 62%    4,779 [69]
2018-11-11 295 38 n/a 333 209 - 4,803 [70]
2018-11-16 319 47 49 415 214 59%    4,430 [71]
2018-11-21 326 47 90 463 217 - 4,668 [72]
2018-11-23 365 47 45 457 236 57%    4,354 [73]
2018-11-26 374 47 74 495 241 57%    4,767 [74]
2018-11-30 392 48 63 503 255 58%    4,820 [75]
2018-12-03 405 48 79 532 268 59%    5,335 [76]
2018-12-07 446 48 95 589 283 57%    6,417 [77]
2018-12-10 452 48 n/a 500 289 58%    6,509 [78]
2018-12-14 483 48 111 642 313 59%    6,695 [79]
2018-12-21 526 48 118 692 347 60%    8,422 [80]
2018-12-28 548 48 52 648 361 61%    7,007 [81]
2019-01-04 575 48 118 741 374 60%    5,047 [82]
2019-01-11 595 49 n/a 644 390 61%    4,937 [83]
2019-01-18 636 49 209 894 416 61%    4,971 [84][85]
2019-01-25 679 54 204 937 459 63%    6,241 [86][87]
2019-02-01 720 54 168 942 481 62%    >7,000   [88][89]
2019-02-10 750 61 148 959 510 63%    7,846 [90][91]
2019-02-18 773 65 135 973 534 64%    6,772 [92][93]
2019-02-24 804 65 219 1,088 546 63%    5,739 [94][95]
2019-03-03 830 65 182 1,077 561 63%    5,613 [96][97]
2019-03-10 856 65 191 1,112 582 63%    4,830 [98][99]
2019-03-17 886 65 231 1,182 598 63%    4,158 [100][101]
2019-03-25 944 65 226 1,235 629 62%    4,132 [102][103]
2019-03-31 1,016 66 279 1,361 676 62%    6,989 [104][105]
2019-04-07 1,080 66 282 1,428 721 63%    7,099 [31]
2019-04-14 1,185 66 269 1,520 803 64%    10,461 [106]

# numbers are subject to revision both up, when new cases are discovered, and down consequently, when tests show cases were not Ebola-related.
DRC Ministry of Public Health
indicates suspected cases were not counted towards CFR

Transition to large-scale outbreakEdit

The Uganda Ministry of Health has issued an alert for extra surveillance as the neighboring outbreak in the DRC is just 100 kilometres (62 mi) away from its border.[107] On 7 August, the DRC Ministry of Public Health indicated that the total count had climbed to almost 90 cases;[108] two days later, on 9 August, it was nearly 100 cases.[109] On 16 August, the United Kingdom indicated it would help with EVD diagnosis and monitoring in the Democratic Republic of the Congo.[110] On 17 August, the WHO reported that "contacts" numbered about 1500 individuals, however there could be more in certain conflict zones in the DRC that can not be reached.[111] Some 954 contacts were successfully followed up on 18 August, however, Mandima Health Zone indicated resistance; as a consequence, contacts were not followed up there per the World Health Organization.[43]

On 4 September, Butembo, a city with almost one million people, logged its first fatality in the Ebola outbreak. The city of Butembo, in the Democratic Republic of the Congo, has trade links to Uganda, which it borders.[112][26]

On 24 September, it was reported that all contact tracing and vaccinations would stop for the foreseeable future in Beni, due to an attack the day before by rebel groups that left several individuals dead.[113] On 25 September, Peter Salama of the World Health Organization indicated that insecurity is obstructing efforts to stop the virus and believes a combination of factors could establish conditions for an epidemic.[114] On 18 October, the Centers for Disease Control and Prevention raised its travelers' alert to the Democratic Republic of the Congo from a level 1 to level 2 for all U.S. travelers.[115] On 26 October, the World Health Organization indicated that half of confirmed cases were not showing any fever symptom, thus making diagnosis more difficult.[65]

On 6 November, the Centers for Disease Control and Prevention indicated that the current outbreak in the east region of the DRC may not be containable due to several factors. This would be the first time since 1976 that an outbreak has not been able to be curbed.[116] Due to various situations surrounding the current EVD outbreak, WHO indicated on 13 November, that the viral outbreak would last at least 6 months.[117]

On 23 November it was reported that due to a steady increase in cases, it is expected that the current EVD outbreak in DRC will overtake the Uganda 2000 outbreak of 425 total cases, to become the second biggest EVD outbreak behind only the West Africa Ebola virus epidemic.[118][18] According to the current available statistics, women are being infected at a higher rate, 60%, than their male counterparts due to the EVD outbreak, a report issued 4 December indicated.[119]

On 29 December the DRC Ministry of Public Health declared "0 new confirmed cases detected because of the paralysis of the activities of the response in Beni, Butembo, Komanda and Mabalako" and no vaccination has occurred for three consecutive days.[120] On 22 January the total case count began to approach 1,000 cases, (951 suspected, probable, confirmed) in the DRC Ministry of Public Health situation report.[121] The graphs below demonstrate the EVD intensity in different locations in the DRC:

On 16 March the director of the Centers for Disease Control and Prevention indicated that the current outbreak in the Democratic Republic of the Congo could last another year, additionally indicating that vaccine supplies could run out.[122]

According to a September 2018 Lancet survey, 25% of respondents in Beni and Butembo believed the Ebola outbreak to be a hoax. These beliefs correlated with decreased likelihood of seeking healthcare or agreeing to vaccination.[123][124] Furthermore, according to the World Health Organization, resistance to vaccination in the Kaniyi health area is ongoing.[104]

Countries with medically evacuated individualsEdit

On 29 December, an American physician that was exposed to the Ebola virus (and who was non-symptomatic) was evacuated, and taken to the University of Nebraska Medical Center.[125][126] On 12 January, the individual was released after 21 days without symptoms.[127]

Bordering countriesEdit

 
Figure 5. Map of Uganda (which borders the DRC)

On 11 August, a UN agency indicated that steps were being taken to assure that those leaving the DRC into Uganda are not infected with Ebola; this is being done via active screening.[2][128] On 13 August, the DRC reported a total of 115 cases of the virus within its borders so far.[2][128] Three individuals in Uganda that were suspected of contracting the virus were tested, with negative results.[129]

On 22 August, it was reported that the government of Uganda had opened two Ebola treatment centers at the border with the Democratic Republic of the Congo, though there are as yet no confirmed cases in the country of Uganda.[130][131]

According to the International Red Cross, a 'most likely scenario' entails an asymptomatic case will at some point enter the country of Uganda undetected among the numerous refugees coming from the DRC.[132] On 20 September Uganda indicated it was ready for immediate vaccination, should the Ebola virus be detected in any individual.[133][134]

On 21 September, officials of the Democratic Republic of the Congo indicated a confirmed case of EVD at Lake Albert, an entry point into Uganda, though no case has been confirmed within Ugandan territory.[135][136]

On 2 November, it was reported that the Ugandan government would start vaccination of health workers along the border with the Democratic Republic of the Congo as a proactive measure against the virus.[137] Other countries that border the Democratic Republic of the Congo are South Sudan and Rwanda.[138] On 2 January 2019 it was reported that refugee movement from the DRC to Uganda had increased after the presidential elections.[139] On 12 February it was reported that 13 individuals had been isolated due to their contact with a suspected Ebola case in Uganda;[140] the lab results came back negative several hours later.[141]

Containment and military conflictEdit

 
Figure 6. Goma, which is the capital of North Kivu province

The area in question, North Kivu, is also currently in the middle of the Kivu Conflict, a military conflict with thousands of displaced refugees.[142][143] The affected area has about one million uprooted people and shares borders with Rwanda and Uganda, with cross border movement because of trade activities. The humanitarian crisis and deterioration of the security situation is expected to affect any response to the outbreak.[144][145] The DRC is expected to hold presidential elections at the end of this year.[146]

There are about 70 armed military groups, among them the Alliance of Patriots for a Free and Sovereign Congo and the Mai-Mayi Nduma défense du Congo-Rénové, in North Kivu. The armed fighting has apparently displaced thousands of individuals.[147] According to WHO, health care workers will be accompanied by military personnel for protection; additionally, ring vaccination may not be possible.[148] On 11 August, it was reported that seven individuals were killed in Mayi-Moya due to a military group, about 24 miles from Beni where there are several EVD cases.[149][150] The WHO is asking for safe passage to those areas that are within conflict zones, so that possible EVD cases may be found.[151]

On 24 August, it was reported that an Ebola-stricken physician had been in contact with some 97 individuals in an inaccessible military area, hence those 97 contacts could not be diagnosed.[152][153]

On 4 September, it was reported that on the outskirts of the city of Beni (one of the areas affected by the EVD outbreak) 2 peacekeepers were attacked and wounded by rebel groups in the area which is part of a larger military conflict.[154] On 23 September, it was reported that 14 individuals were killed in a military attack in the city of Beni, which is an area affected by the current EVD outbreak.[155] In September 2018, the World Health Organization's Deputy Director-General for Emergency Preparedness and Response described the combination of military conflict and civilian distress as a potential "perfect storm" that could lead to a rapid worsening of the outbreak.[8][9] On 5 October, the Nobel Peace Prize was awarded to Denis Mukwege, who tends to the female victims of the ongoing internal armed conflict in the Democratic Republic of the Congo.[156]

On 20 October, an armed rebel group in the DRC killed some 13 civilians and took 12 children as hostages. This attack occurred in Beni, the current epicenter of the outbreak.[157][158] On 11 November, six people were killed in an attack by an armed rebel group in Beni; as a consequence vaccinations were suspended there.[159][160] A recent position paper by a 'think tank' on the violence and health problem (EVD outbreak) indicates the situation in the DRC may get worse depending on the result and response of presidential elections in the country in 2018.[161] Yet another attack reported on 17 November, in Beni by an armed rebel group forced the cessation of EVD containment efforts and WHO staff to evacuate to another city in Democratic Republic of the Congo for the time being.[162] Beni continues to be the site of attacks by militant groups as 18 civilians were killed on 6 December, according to a report[163] On 22 December it was reported that elections for president of the Democratic Republic of the Congo would go forward despite the EVD outbreak, including in the Ebola-stricken area of Beni.[164] Four days later, on 26 December, the DRC government reversed itself to indicate those Ebola-stricken areas, such as Beni, would not vote for several months;[165] as a consequence election protesters ransacked an Ebola assessment center in Beni just 24 hours later.[166][167][168] Post election tensions continued when it was reported that the DRC government had cut-off internet connections for the population, as the vote results were yet to be released.[169]

On 29 December, Oxfam said it would suspend its work due to the ongoing violence in the DRC;[170] on the same day, the International Rescue Committee suspended their Ebola support efforts as well.[171]

On 18 January the African Union indicated that presidential election results announcements should be suspended in the Democratic Republic of the Congo, and have furthermore decided not to travel to the DRC.[172]

On 28 February it was reported that an attack was carried out in Butembo, specifically at an Ebola treatment center; this would be the second in a week as a similar attack occurred in Katwa on Sunday. The motives behind the attacks are as yet unclear.[173][174]

VirologyEdit

 
Figure 7. Fruit bats (Group of Rousettus aegyptiacus)

Zaire ebolavirus strain is the most lethal of the six known strains (including the newly discovered Bombali strain);[175] it is fatal in up to 90% of cases.[176] Both Ebola and Marburg virus are part of the Filoviridae family.[177]

The filovirus genome contains seven genes, including VP40.[178] The natural reservoir of the virus is thought to be the African fruit bat,[179] which is used in many parts of Africa as bushmeat.[180]

Viral mechanismEdit

A significant part of the actual EVD infection is based on immune suppression. When an individual is infected the pathophysiological process indicates that as systemic inflammation sets in there are coagulation problems, as well as vascular and the aforementioned immune system issues.[181]

TreatmentEdit

On 27 August, the World Health Organization evaluated the benefits and risks of drug treatment for EVD: Remdesivir, ZMapp, REGN3470-3471-3479, mAb114 and favipiravir.[182] mAb114 (which is a monoclonal antibody) is being used for the first time to treat infected individuals during this EVD outbreak.[183] An alternative treatment of ZMapp has not been used because it requires storage at −20 °C (−4 °F).[2]

On 25 November, the Democratic Republic of the Congo gave approval to start clinical trials for Ebola (EVD) treatment. Medical authorities will not choose which of the four experimental treatments will be given to an individual; instead it will be randomized.[184]

VaccinationEdit

 
Figure 8. Number of vaccinated people in the epidemic area DRC[185]

On 8 August 2018, the process of vaccination began with rVSV-ZEBOV Ebola vaccine.[186] While several studies have shown the vaccine to be safe and protective against the virus, additional research is needed before it can be licensed. Consequently, the WHO reports that it is being used under a ring vaccination strategy with what is known as “compassionate use” to protect persons at highest risk of the Ebola outbreak.[187]

Pregnant and lactating womenEdit

Based on a lack of evidence about the safety of the vaccine during pregnancy, the DRC ministry of health and the WHO decided to not vaccinate women who are pregnant or lactating. This decision has been criticized as "utterly indefensible" from an ethical perspective by some authorities. They note that as caregivers of the sick, pregnant and lactating women are more likely to contact Ebola. They also note that since it is known that almost 100% of pregnant women who contact Ebola will die, a safety concern should not be a deciding factor.[188]

Vaccine stockpileEdit

The Democratic Republic of the Congo Ministry of Public Health reported on 16 August that 316 individuals had been vaccinated.[189] On 24 August, the DRC indicated it had vaccinated 2,957 individuals, including 1,422 in Mabalako against the Ebola virus.[190] By late October more than 20,000 individuals had been vaccinated.[191] In December Dr Peter Salama, who is Deputy Director-General of Emergency Preparedness and Response for WHO, reported that the current 300,000 vaccine stockpile may not be enough to contain this EVD outbreak; additionally it takes several months to make more of the Zaire EVD vaccine (rVSV-ZEBOV).[192][193] On 11 December it was reported that the stock of vaccine in Beni was 4,290 doses.[31]

EffectivenessEdit

In April 2019, the WHO published the preliminary results of its research, in association with the DRC's Institut National pour la Recherche Biomedicale, into the effectiveness of the ring vaccination program, stating that the rVSV-ZEBOV-GP vaccine had been 97.5% effective at stopping Ebola transmission, relative to no vaccination.[194][195]

Treatment centresEdit

On 14 August, it was reported that the Mangina Ebola Treatment Center was now operational.[196][197] A fourth Ebola Treatment Center (after those in Mangina, Beni and Butembo) was inaugurated on 18 September in Makeke in the Mandima Health Zone of Ituri Province.[198] Makeke is less than five kilometers from Mangina along a well-traveled local road; the site had been proposed in August when it appeared that a second Ebola Treatment Center would be needed in the area, and space was insufficient in Mangina itself to accommodate one.[199] By mid-September, however, there had been only two additional cases in the Mandima Health Zone, and only sporadic cases were being reported in the Mabalako Health Zone.[200]

Healthcare workersEdit

Health workers must don personal protection equipment during treatment of those affected by the virus, as well as various other tasks.[201] On 3 September, WHO stated that 16 health workers had contracted the virus.[48]

As of 10 December, the WHO reported that the current DRC outbreak had affected 49 healthcare workers as confirmed cases, and 15 had died.[78]

PrognosisEdit

In terms of prognosis, aside from the possible effects of post-Ebola syndrome,[202] there is also the reality of survivors returning to communities where they might be shunned due to the fear many have in the respective areas of the Ebola virus,[203][204] hence psychosocial assistance is needed.[205]

Post-Ebola syndrome signs and symptoms in an individual may include, but are not limited to the following:[206][207]

HistoryEdit

 
Figure 9. Colorized scanning electron micrograph of Ebola virus particles (green) found both as extracellular particles and budding particles from a chronically-infected African green monkey kidney cell (blue); 20,000x magnification

The Ebola virus disease outbreak in Zaire (Yambuku) started in late 1976, and was the second outbreak ever after the earlier one in Sudan the same year.[208][209] On 1 August 2018, the tenth Ebola outbreak was declared in the Democratic Republic of Congo, only a few days after the prior outbreak in the same country had been declared over on 24 July.[6][7]

World Health Organization chief Tedros Adhanom Ghebreyesus indicated on 15 August that the current outbreak in DRC may be worse than the West Africa outbreak of 2013–2016,[210] due to several factors.[211]

The table below indicates the ten outbreaks that have occurred in the Democratic Republic of the Congo since 1976:

Table 2.
Timeline of Ebola outbreaks in the Democratic Republic of the Congo (formerly Zaire)
VT
Date
Country Major location Outbreak information Source
Strain Cases Deaths CFR
Aug 1976   Zaire Yambuku EBOV 318 280 88% [212]
Jun 1977   Zaire Tandala EBOV 1 1 100% [213][214]
May–Jul 1995   Zaire Kikwit EBOV 315 254 81% [215]
Aug–Nov 2007   Democratic Republic of the Congo Kasai-Occidental EBOV 264 187 71% [216]
Dec 2008–Feb 2009   Democratic Republic of the Congo Kasai-Occidental EBOV 32 14 45% [217]
Jun–Nov 2012   Democratic Republic of the Congo Orientale BDBV 77 36 47% [213]
Aug–Nov 2014   Democratic Republic of the Congo Tshuapa EBOV 66 49 74% [218]
May–Jul 2017   Democratic Republic of the Congo Likati EBOV 8 4 50% [219]
Apr–Jul 2018   Democratic Republic of the Congo Bikoro EBOV 54 33 61% [220]
Aug 2018–present   Democratic Republic of the Congo Kivu EBOV ongoing ongoing ongoing

This map and graph also show previous EVD outbreaks in the area of central Africa, which includes the Democratic Republic of the Congo. The graph is interim as total cases and deaths number may increase as the outbreak expands.[15] This current outbreak is the biggest of the ten recorded outbreaks that have occurred in the DRC.[221]

Figure 10. Ebola (and Marburg virus) outbreaks on the African continent[17][222]

Until the current outbreak in North Kivu in 2018, no outbreak had surpassed 320 total cases. As of 24 February 2019, the current outbreak has surpassed 1,000 total cases (1,048) and has yet to be brought under control.[223][213]

 
Figure 11. Democratic Republic of the Congo EVD outbreaks 1976-November 9, 2018 (total cases for this date does not reflect 52 suspected cases)[15][35]
(Uganda has second most EVD cases '00-'01/425[224]
West African Ebola virus epidemic '13-'16/ >28,000[225])

ResponseEdit

During the Ebola outbreak in Democratic Republic of the Congo a number of organizations have come forward to help in different capacities: CARITAS DRC, CARE International, Cooperazione Internationale (COOPE), Catholic Organization for Relief and Development Aid (CORDAID/PAP-DRC), International Rescue Committee (IRC), Médecins Sans Frontières (MSF), Oxfam, International Federation of Red Cross and Red Crescent Societies (IFRC), International Committee of the Red Cross (ICRC), and Samaritan's Purse.[50]

On 12 April 2019, the WHO Emergency Committee was reconvened by the WHO Director-General after an increase in the rate of new cases, and determined that the outbreak still failed to meet the criteria for a Public Health Emergency of International Concern.[12][226]

See alsoEdit

NotesEdit

  1. ^ Ituri province was added to N. Kivu province, in terms of viral infection, when the first case of EVD was confirmed on 13 August.[2]

ReferencesEdit

  1. ^ a b c d e "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Mercredi 17 avril 2019". us13.campaign-archive.com. Retrieved 17 April 2019.
  2. ^ a b c d e "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Lundi 13 août 2018". mailchi.mp. Retrieved 17 August 2018.
  3. ^ Editorial, Reuters (August 2018). "Congo declares new Ebola outbreak in eastern province". Reuters. Retrieved 1 August 2018.
  4. ^ "Congo announces 4 new Ebola cases in North Kivu province". Washington Post. Retrieved 1 August 2018.
  5. ^ "Cluster of presumptive Ebola cases in North Kivu in the Democratic Republic of the Congo". World Health Organization. Retrieved 2 August 2018.
  6. ^ a b "Media Advisory: Expected end of Ebola outbreak". ReliefWeb. Retrieved 1 August 2018.
  7. ^ a b Weber, Lauren (1 August 2018). "New Ebola Outbreak Confirmed In Democratic Republic Of Congo". Huffington Post. Retrieved 1 August 2018.
  8. ^ a b Belluz, Julia (25 September 2018). "An Ebola "perfect storm" is brewing in Democratic Republic of the Congo". Vox. Retrieved 26 September 2018.
  9. ^ a b "Ebola-hit DRC faces 'perfect storm' as uptick in violence halts WHO operation - Democratic Republic of the Congo". ReliefWeb. 25 September 2018. Retrieved 26 September 2018.
  10. ^ Spinney, Laura (18 January 2019). "In Congo, fighting a virus and a groundswell of fake news". Science. 363 (6424): 213–214. doi:10.1126/science.363.6424.213. ISSN 1095-9203. PMID 30655420.
  11. ^ "Ebola virus disease – Democratic Republic of the Congo". World Health Organization. Retrieved 28 September 2018.
  12. ^ a b "Statement on the meeting of the International Health Regulations (2005) Emergency Committee for Ebola virus disease in the Democratic Republic of the Congo on 12th April 2019". World Health Organization. 12 April 2019. Retrieved 12 April 2019.
  13. ^ "UN calls for end to Congo fighting to combat Ebola outbreak". Washington Post. Retrieved 4 October 2018.
  14. ^ Editorial, Reuters (2018-10-15). "Congo confirms 33 Ebola cases in past week, of whom 24 died". Reuters. Retrieved 16 October 2018.
  15. ^ a b c "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Vendredi 9 novembre 2018". mailchi.mp. Retrieved 9 November 2018.
  16. ^ "Current Ebola Outbreak Is Worst in Congo's History: Ministry". usnews.com. Us News and World report. Retrieved 10 November 2018.
  17. ^ a b "Ebola Virus Disease Distribution Map: Cases of Ebola Virus Disease in Africa Since 1976 | 2014-2016 Outbreak West Africa | History | Ebola (Ebola Virus Disease) | CDC". www.cdc.gov. 22 May 2018. Retrieved 10 October 2018.
  18. ^ a b "Operations Dashboard for ArcGIS". who.maps.arcgis.com. Retrieved 25 November 2018.
  19. ^ Weber, Lauren (29 November 2018). "The Ebola Outbreak In Congo Just Became The Second Largest Ever". Huffington Post. Retrieved 29 November 2018.
  20. ^ "Ebola virus disease". www.who.int. Retrieved 13 February 2019.
  21. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Mercredi 13 février 2019". us13.campaign-archive.com. Retrieved 13 February 2019.
  22. ^ Press, Saleh Mwanamilongo, Associated. "Congo announces 4 new Ebola cases in North Kivu province". Retrieved 5 August 2018.
  23. ^ "The Democratic Republic of the Congo: Ebola Virus Disease Outbreak – Epidemiological Situation DG ECHO Daily Map | 3 August 2018". ReliefWeb. Retrieved 5 August 2018.
  24. ^ Dyer, Owen (2018). "Ebola: new outbreak appears in Congo a week after epidemic was declared over". The BMJ. 362: k3421. doi:10.1136/bmj.k3421. PMID 30087112. Retrieved February 2, 2019.
  25. ^ "UNICEF DR Congo (North Kivu) Ebola Situation Report #1 - 3 August 2018". ReliefWeb. Retrieved 4 August 2018.
  26. ^ a b "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Mercredi 5 septembre 2018 (ERRATUM)". mailchi.mp. Retrieved 6 September 2018.
  27. ^ a b "Updated: Deadly Ebola surfaces in Africa's center yet again". Science | AAAS. 1 August 2018. Retrieved 3 August 2018.
  28. ^ "DRC: MSF treats 65 people with Ebola in first month of intervention in North Kivu". ReliefWeb. Retrieved 7 September 2018.
  29. ^ "Oxfam responds to the new Ebola Outbreak in Beni, North Kivu, DRC". ReliefWeb. Retrieved 2 August 2018.
  30. ^ "Ebola virus disease – Democratic Republic of the Congo". World Health Organization. Retrieved 6 August 2018.
  31. ^ a b c "Outbreaks and Emergencies Bulletin, Week 14: 01 - 07 April 2019". WHO | Regional Office for Africa. Retrieved 8 April 2019.
  32. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Samedi 10 novembre 2018". mailchi.mp. Retrieved 10 November 2018.
  33. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 23 décembre 2018". us13.campaign-archive.com. Retrieved 23 December 2018.
  34. ^ "World Population Prospects - Population Division - United Nations". population.un.org. Retrieved 23 December 2018.
  35. ^ a b "WHO | World Health Organization". www.who.int. Retrieved 13 August 2018.
  36. ^ "EBOLA RDC - Communication spéciale du Ministre de la Santé en rapport à la situation épidémiologique dans la Province du Nord-Kivu". mailchi.mp. Retrieved 19 August 2018.
  37. ^ "WHO AFRO Outbreaks and Other Emergencies, Week 31: 28 July - 3 August (Data as reported by 17:00; 3 August 2018)". ReliefWeb. Retrieved 6 August 2018.
  38. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Samedi 4 août 2018". mailchi.mp. Retrieved 5 August 2018.
  39. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 1". ReliefWeb. Retrieved 8 August 2018.
  40. ^ News, ABC. "Congo's health ministry confirms 3 more cases of Ebola". ABC News. Retrieved 8 August 2018.
  41. ^ "Outbreaks and Emergencies Bulletin, Week 32: 04 - 10 August 2018". WHO | Regional Office for Africa. Retrieved 19 August 2018.
  42. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 2". ReliefWeb. Retrieved 15 August 2018.
  43. ^ a b "Outbreaks and Emergencies Bulletin, Week 33: 11 - 17 August 2018". WHO | Regional Office for Africa. Retrieved 20 August 2018.
  44. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 3". ReliefWeb. Retrieved 22 August 2018.
  45. ^ "WHO AFRO Outbreaks and Other Emergencies, Week 34: 18 - 24 August (Data as reported by 17:00; 24 August 2018)". ReliefWeb. Retrieved 27 August 2018.
  46. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 4". ReliefWeb. Retrieved 28 August 2018.
  47. ^ "Outbreaks and Emergencies Bulletin, Week 35: 25 - 31 August 2018". WHO | Regional Office for Africa. Retrieved 3 September 2018.
  48. ^ a b "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 5". ReliefWeb. Retrieved 4 September 2018.
  49. ^ "Outbreaks and Emergencies Bulletin, Week 36: 1 - 7 September 2018". WHO | Regional Office for Africa. Retrieved 10 September 2018.
  50. ^ a b "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 6". ReliefWeb. Retrieved 12 September 2018.
  51. ^ "Ebola virus disease – Democratic Republic of the Congo: Disease outbreak news - 7 September 2018". ReliefWeb. Retrieved 12 September 2018.
  52. ^ "Outbreaks and Emergencies Bulletin, Week 37: 8 - 14 September 2018". WHO | Regional Office for Africa. Retrieved 17 September 2018.
  53. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 7 - Democratic Republic of the Congo". ReliefWeb. Retrieved 19 September 2018.
  54. ^ "DR Congo - 2018 Ebola Outbreak in North Kivu Province (September 17, 2018 update) - Democratic Republic of the Congo". ReliefWeb. Retrieved 19 September 2018.
  55. ^ "Outbreaks and Emergencies Bulletin, Week 38: 15 - 21 September 2018". WHO | Regional Office for Africa. Retrieved 24 September 2018.
  56. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 8 - Democratic Republic of the Congo". ReliefWeb. Retrieved 26 September 2018.
  57. ^ "Outbreaks and Emergencies Bulletin, Week 39: 22 - 28 September 2018". WHO | Regional Office for Africa. Retrieved 1 October 2018.
  58. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 9 - Democratic Republic of the Congo". ReliefWeb. Retrieved 4 October 2018.
  59. ^ "Outbreaks and Emergencies Bulletin, Week 40: 29 September - 05 October 2018". WHO | Regional Office for Africa. Retrieved 8 October 2018.
  60. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 10 - Democratic Republic of the Congo". ReliefWeb. Retrieved 9 October 2018.
  61. ^ "Outbreaks and Emergencies Bulletin, Week 41: 06 - 12 October 2018". WHO | Regional Office for Africa. Retrieved 15 October 2018.
  62. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 11 - Democratic Republic of the Congo". ReliefWeb. Retrieved 18 October 2018.
  63. ^ "Outbreaks and Emergencies Bulletin, Week 42: 13 - 19 October 2018". WHO | Regional Office for Africa. Retrieved 22 October 2018.
  64. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 12 - Democratic Republic of the Congo". ReliefWeb. Retrieved 23 October 2018.
  65. ^ a b "Outbreaks and Emergencies Bulletin, Week 43: 20 - 26 October 2018". WHO | Regional Office for Africa. Retrieved 29 October 2018.
  66. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 13 - Democratic Republic of the Congo". ReliefWeb. Retrieved 30 October 2018.
  67. ^ "Outbreaks and Emergencies Bulletin, Week 44: 27 October - 02 November 2018". WHO | Regional Office for Africa. Retrieved 5 November 2018.
  68. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 14 - Democratic Republic of the Congo". ReliefWeb. Retrieved 7 November 2018.
  69. ^ "Outbreaks and Emergencies Bulletin, Week 45: 03 - 09 November 2018". WHO | Regional Office for Africa. Retrieved 12 November 2018.
  70. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 15 - Democratic Republic of the Congo". ReliefWeb. Retrieved 13 November 2018.
  71. ^ a b "Outbreaks and Emergencies Bulletin, Week 46: 10 - 16 November 2018". WHO | Regional Office for Africa. Retrieved 19 November 2018.
  72. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 16 - Democratic Republic of the Congo". ReliefWeb. Retrieved 22 November 2018.
  73. ^ "Outbreaks and Emergencies Bulletin, Week 47: 17 - 23 November 2018". WHO | Regional Office for Africa. Retrieved 27 November 2018.
  74. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 17 - Democratic Republic of the Congo". ReliefWeb. Retrieved 28 November 2018.
  75. ^ "Outbreaks and Emergencies Bulletin, Week 48: 24 - 30 November 2018". WHO | Regional Office for Africa. Retrieved 3 December 2018.
  76. ^ "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 18 - Democratic Republic of the Congo". ReliefWeb. Retrieved 5 December 2018.
  77. ^ "Outbreaks and Emergencies Bulletin, Week 49: 01 - 07 December 2018". WHO | Regional Office for Africa. Retrieved 11 December 2018.
  78. ^ a b "Democratic Republic of Congo: Ebola Virus Disease - External Situation Report 19 - Democratic Republic of the Congo". ReliefWeb. Retrieved 12 December 2018.
  79. ^ "Outbreaks and Emergencies Bulletin, Week 50: 08 - 14 December 2018". WHO | Regional Office for Africa. Retrieved 17 December 2018.
  80. ^ "Outbreaks and Emergencies Bulletin, Week 51: 15 - 21 December 2018". WHO | Regional Office for Africa. Retrieved 24 December 2018.
  81. ^ "Outbreaks and Emergencies Bulletin, Week 52: 22 - 28 December 2018". WHO | Regional Office for Africa. Retrieved 31 December 2018.
  82. ^ "Outbreaks and Emergencies Bulletin, Week 01: 29 December 2018 - 04 January 2019". WHO | Regional Office for Africa. Retrieved 7 January 2019.
  83. ^ "Outbreaks and Emergencies Bulletin, Week 02: 05 - 11 January 2019". WHO | Regional Office for Africa. Retrieved 14 January 2019.
  84. ^ "Outbreaks and Emergencies Bulletin, Week 03: 12 - 18 January 2019". WHO | Regional Office for Africa. Retrieved 21 January 2019.
  85. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Vendredi 18 janvier 2019". us13.campaign-archive.com. Retrieved 21 January 2019. WHO did not report suspected cases, added same day reference from DRC Ministry of Public Health
  86. ^ "Outbreaks and Emergencies Bulletin, Week 04: 19 - 25 January 2019". WHO | Regional Office for Africa. Retrieved 29 January 2019.
  87. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Vendredi 25 janvier 2019". us13.campaign-archive.com. Retrieved 29 January 2019.
  88. ^ "Outbreaks and Emergencies Bulletin, Week 05: 26 January - 01 February 2019". WHO | Regional Office for Africa. Retrieved 4 February 2019.
  89. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Vendredi 1 février 2019". us13.campaign-archive.com. Retrieved 4 February 2019.
  90. ^ "Outbreaks and Emergencies Bulletin, Week 06: 04 - 10 February 2019". WHO | Regional Office for Africa. Retrieved 11 February 2019.
  91. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 10 février 2019". us13.campaign-archive.com. Retrieved 10 February 2019.
  92. ^ "Outbreaks and Emergencies Bulletin, Week 07: 11 - 17 February 2019". WHO | Regional Office for Africa. Retrieved 18 February 2019.
  93. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 17 février 2019". us13.campaign-archive.com. Retrieved 18 February 2019.
  94. ^ "Outbreaks and Emergencies Bulletin, Week 08: 18 - 24 February 2019". WHO | Regional Office for Africa. Retrieved 25 February 2019.
  95. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Samedi 23 février 2019". us13.campaign-archive.com. Retrieved 25 February 2019.
  96. ^ "Outbreaks and Emergencies Bulletin, Week 09: 25 February - 03 March 2019". WHO | Regional Office for Africa. Retrieved 4 March 2019.
  97. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 3 mars 2019". us13.campaign-archive.com. Retrieved 6 March 2019.
  98. ^ "Outbreaks and Emergencies Bulletin, Week 10: 04 - 10 March 2019". WHO | Regional Office for Africa. Retrieved 11 March 2019.
  99. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 10 mars 2019". us13.campaign-archive.com. Retrieved 10 March 2019.
  100. ^ "Outbreaks and Emergencies Bulletin, Week 11: 11 - 17 March 2019". WHO. WHO. Retrieved 18 March 2019.
  101. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 17 mars 2019". us13.campaign-archive.com. Retrieved 17 March 2019.
  102. ^ "Outbreaks and Emergencies Bulletin, Week 12: 18 - 24 March 2019". WHO | Regional Office for Africa. Retrieved 26 March 2019.
  103. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Lundi 25 mars 2019". us13.campaign-archive.com. Retrieved 26 March 2019.
  104. ^ a b "Outbreaks and Emergencies Bulletin, Week 13: 25 - 31 March 2019". WHO | Regional Office for Africa. Retrieved 1 April 2019.
  105. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Dimanche 31 mars 2019". us13.campaign-archive.com. Retrieved 31 March 2019.
  106. ^ "Outbreaks and Emergencies Bulletin, Week 15: 08 - 14 April 2019". WHO | Regional Office for Africa. Retrieved 16 April 2019.
  107. ^ "Ebola: Health ministry issues alert". ReliefWeb. Retrieved 7 August 2018.
  108. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Mardi 7 août 2018". us13.campaign-archive.com. Retrieved 8 August 2018.
  109. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Jeudi 9 août 2018". mailchi.mp. Retrieved 17 August 2018.
  110. ^ "UK response to the Ebola outbreak in North Kivu, DRC". GOV.UK. Retrieved 16 August 2018.
  111. ^ Editorial, Reuters (2018-08-17). "WHO expects more Ebola cases in Congo, can't reach no-go areas". Reuters. Retrieved 17 August 2018.
  112. ^ Gulland, Anne (6 September 2018). "Ebola death in city of one million prompts fears of urban spread". The Telegraph. Retrieved 6 September 2018.
  113. ^ "Rebel attack halts DR Congo Ebola work". BBC News. 24 September 2018. Retrieved 24 September 2018.
  114. ^ Schlein, Lisa. "WHO Warns Ebola Spreading in Eastern DR Congo". VOA. Retrieved 25 September 2018. A perfect storm of active conflict limiting our ability to access civilians, distress by segments of the community already traumatized by decades of conflict and of murder, driven by a fear of a terrifying disease
  115. ^ "Ebola in Democratic Republic of the Congo - Alert - Level 2, Practice Enhanced Precautions - Travel Health Notices | Travelers' Health | CDC". wwwnc.cdc.gov. Retrieved 19 October 2018.
  116. ^ "CDC director warns that Congo's Ebola outbreak may not be containable". Washington Post. Retrieved 6 November 2018.
  117. ^ "Congo's Ebola outbreak to last at least 6 more months". CNBC. 13 November 2018. Retrieved 13 November 2018.
  118. ^ "Congo's Ebola outbreak almost second highest ever". Axios. Retrieved 24 November 2018.
  119. ^ "Congo's Worst Ebola Outbreak Hits Women Especially Hard - Democratic Republic of the Congo". ReliefWeb. Retrieved 5 December 2018.
  120. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Samedi 29 décembre 2018". us13.campaign-archive.com. Retrieved 29 December 2018.
  121. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Mardi 22 janvier 2019". us13.campaign-archive.com. Retrieved 22 January 2019.
  122. ^ Grady, Denise (16 March 2019). "Ebola Epidemic in Congo Could Last Another Year, C.D.C. Director Warns". The New York Times. Retrieved 17 March 2019.
  123. ^ Vinck, Patrick; Pham, Phuong N; Bindu, Kenedy K; et al. (March 2019). "Institutional trust and misinformation in the response to the 2018–19 Ebola outbreak in North Kivu, DR Congo: a population-based survey". The Lancet Infectious Diseases. doi:10.1016/S1473-3099(19)30063-5. PMID 30928435.
  124. ^ "1 in 4 people near Congo's Ebola outbreak believe virus isn't real, new study says". ABC News. 29 March 2019. Retrieved 1 April 2019.
  125. ^ Diamond, Dan. "Doctor exposed to Ebola brought to United States". POLITICO. Retrieved 29 December 2018.
  126. ^ "Doctor possibly exposed to Ebola being monitored in Nebraska". Washington Examiner. 29 December 2018. Retrieved 29 December 2018.
  127. ^ "American monitored for possible Ebola did not have disease, released". NBC News. Retrieved 14 January 2019.
  128. ^ a b Schlein, Lisa. "UN Stepping Up Ebola Screening of Refugees Fleeing DR Congo". VOA. Retrieved 14 August 2018.
  129. ^ "Three alert cases in western Uganda tested negative for Ebola - Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 16 August 2018.
  130. ^ "Uganda opens Ebola treatment units at border with DRC - Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 23 August 2018.
  131. ^ "Uganda opens Ebola treatment units at border with DRC". Premium Times Nigeria. 23 August 2018. Retrieved 23 August 2018.
  132. ^ "Uganda: Ebola Preparedness Emergency Plan of Action (EPoA) - DREF Operation n° MDRUG041". ReliefWeb. Retrieved 12 September 2018.
  133. ^ "Uganda prepares to vaccinate against Ebola in case the virus strikes the country - Uganda". ReliefWeb. Retrieved 20 September 2018.
  134. ^ "WHO Setting Up Ebola Vaccination Strategy In Uganda After Outbreak In DRC". article.worldnews.com. Retrieved 20 September 2018.
  135. ^ "Congo confirms Ebola case at Ugandan border". Channel NewsAsia. Retrieved 21 September 2018.
  136. ^ Editorial, Reuters (2018-09-21). "Congo confirms Ebola case at Ugandan border". Reuters. Retrieved 21 September 2018.
  137. ^ Athumani, Halima. "Uganda to Deploy Ebola Vaccine to Health Workers on DRC Border". VOA. Retrieved 2 November 2018.
  138. ^ News, A. B. C. (7 December 2018). "2nd deadliest Ebola outbreak in history spreads to major city". ABC News. Retrieved 7 December 2018.
  139. ^ "Flood of refugees fleeing Congo raises fears of spreading Ebola". www.cbsnews.com. 2 January 2019. Retrieved 7 January 2019.
  140. ^ "Uganda quarantines 13 people who contacted dead body of suspected Ebola case - Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 12 February 2019.
  141. ^ "Results of suspected Ebola case in Uganda turn negative: health official - Xinhua | English.news.cn". www.xinhuanet.com. Retrieved 13 February 2019.
  142. ^ "Ebola In A Conflict Zone". NPR.org. Retrieved 2 August 2018.
  143. ^ "Congo Ebola outbreak compounds already dire humanitarian crisis". ReliefWeb. Retrieved 3 August 2018.
  144. ^ "Ebola virus disease – Democratic Republic of the Congo: Disease outbreak news, 4 August 2018". ReliefWeb. Retrieved 5 August 2018.
  145. ^ "Conflict in new Ebola zone of DR Congo exacerbates complexity of response: WHO emergency response chief". UN News. 3 August 2018. Retrieved 5 August 2018.
  146. ^ "DRC's struggle for democracy enters new era". www.aljazeera.com. Retrieved 25 September 2018.
  147. ^ "Atrocity Alert, No. 116, 1 August 2018". ReliefWeb. Retrieved 6 August 2018.
  148. ^ "Out of the frying pan, into the fire with a new Ebola outbreak in Congo". Science | AAAS. 6 August 2018. Retrieved 6 August 2018.
  149. ^ "Congo's latest Ebola outbreak taking place in a war zone". thestate. Retrieved 11 August 2018.
  150. ^ "Vaccinations underway in Congo's latest Ebola outbreak | CBC News". CBC. Retrieved 11 August 2018.
  151. ^ "WHO calls for free and secure access in responding to Ebola outbreak in the Democratic Republic of the Congo". ReliefWeb. Retrieved 12 August 2018.
  152. ^ "DRC: Doctor stricken with Ebola in rebel stronghold". www.aljazeera.com. Retrieved 24 August 2018.
  153. ^ Burke, Jason (24 August 2018). "Ebola: medics brace for new cases as DRC outbreak spreads". the Guardian. Retrieved 24 August 2018.
  154. ^ Editorial, Reuters (2018-09-04). "Rebels ambush South African peacekeepers in Congo Ebola zone". Reuters. Retrieved 4 September 2018.
  155. ^ "Rebel Attack in Congo Ebola Zone Kills at Least 14 Civilians". VOA. Retrieved 23 September 2018.
  156. ^ "Nobel prize for Congo surgeon exposes region's deadly threat". macon. Retrieved 6 October 2018.
  157. ^ "Congo rebels kill 13, abduct children at Ebola treatment center". New York Post. 21 October 2018. Retrieved 21 October 2018.
  158. ^ Press, Associated. "Congo Rebels Kill 13, Abduct Kids at Ebola Outbreak". VOA. Retrieved 21 October 2018.
  159. ^ "Rebels kill six, kidnap five in east DRC". News24. 2018-11-12. Retrieved 12 November 2018.
  160. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Lundi 12 novembre 2018". mailchi.mp. Retrieved 12 November 2018.
  161. ^ "North Kivu's Ebola Outbreak at Day 90: What Is to Be Done?". www.csis.org. Retrieved 15 November 2018.
  162. ^ "Anti-Ebola efforts suspended amid violence". BBC News. 17 November 2018. Retrieved 17 November 2018.
  163. ^ "Militants kill at least 18 civilians in Congo's Ebola zone". Reuters. 7 December 2018. Retrieved 7 December 2018.
  164. ^ "Voting will take place in DR Congo's Ebola-hit region: official | DR Congo News | Al Jazeera". www.aljazeera.com. Retrieved 25 December 2018.
  165. ^ Mwanamilongo, Saleh; Boussion, Mathilde (26 December 2018). "Congo delays Sunday's election for months in Ebola zone". AP NEWS. Retrieved 27 December 2018.
  166. ^ "Protesters attack DR Congo Ebola centre". BBC News. 27 December 2018. Retrieved 27 December 2018.
  167. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Jeudi 27 décembre 2018". us13.campaign-archive.com. Retrieved 27 December 2018.
  168. ^ "Statement on disruptions to the Ebola response in the Democratic Republic of the Congo". www.who.int. Retrieved 28 December 2018.
  169. ^ "Warning of 'Fictitious' Election Results Online, Congo Cuts Internet for 2nd Day". The New York Times. 1 January 2019. Retrieved 2 January 2019.
  170. ^ "Oxfam suspends Ebola work amid protests over Democratic Republic of Congo vote delays". Sky News. Retrieved 29 December 2018.
  171. ^ "Election-related violence in Democratic Republic of Congo forces IRC to temporarily suspend life-saving Ebola response programming". International Rescue Committee (IRC). 29 December 2018. Retrieved 29 December 2018.
  172. ^ CNN, Stephanie Busari and Bukola Adebayo. "African Union calls for suspension of DR Congo election results announcement". CNN. Retrieved 22 January 2019.
  173. ^ "Congo Ebola Center Set on Fire After Armed Attack". VOA. Retrieved 1 March 2019.
  174. ^ Feb 28, The Associated Press · Posted; February 28, The Associated Press · Posted. "Doctors Without Borders forced to close Ebola clinics in Congo after attacks | CBC News". CBC. Retrieved 1 March 2019.
  175. ^ "New Ebola species is reported for first time in a decade - STAT". statnews.com. 27 July 2018. Retrieved 27 July 2018.
  176. ^ Rewar, Suresh; Mirdha, Dashrath (1 November 2014). "Transmission of Ebola Virus Disease: An Overview". Annals of Global Health. 80 (6): 444–451. doi:10.1016/j.aogh.2015.02.005. ISSN 2214-9996. PMID 25960093. Retrieved 5 August 2018.
  177. ^ "Filoviridae | Viral Hemorrhagic Fevers (VHFs) | CDC". www.cdc.gov. Retrieved 5 August 2018.
  178. ^ Strauss, James H. Strauss, Ellen G. (2007). Viruses and human disease (2nd ed.). Oxford: Academic. p. 137. ISBN 9780123737410. Retrieved 5 August 2018. – via ScienceDirect (Subscription may be required or content may be available in libraries.)
  179. ^ Gonzalez, J. P.; Pourrut, X.; Leroy, E. (2007). "Ebolavirus and other filoviruses". Current Topics in Microbiology and Immunology. 315: 363–387. doi:10.1007/978-3-540-70962-6_15. ISBN 978-3-540-70961-9. ISSN 0070-217X. PMID 17848072.
  180. ^ "Why West Africans keep hunting and eating bush meat despite Ebola concerns". Washington Post. Retrieved 5 August 2018.
  181. ^ Feldmann, Heinz; Geisbert, Thomas W (5 March 2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–862. doi:10.1016/S0140-6736(10)60667-8. ISSN 0140-6736. PMC 3406178. PMID 21084112.
  182. ^ "Notes for the record: Consultation on Monitored Emergency Use of Unregistered and Investigational Interventions (MEURI) for Ebola Virus Disease (EVD)" (PDF). World Health Organization. Retrieved 11 September 2018.
  183. ^ "NIH begins testing Ebola treatment in early-stage trial". National Institutes of Health (NIH). 23 May 2018. Retrieved 15 October 2018.
  184. ^ Editorial, Reuters (2018-11-24). "Congo approves clinical trials for Ebola treatments". Reuters. Retrieved 25 November 2018.
  185. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Lundi 31 décembre 2018". us13.campaign-archive.com. Retrieved 31 December 2018.
  186. ^ "Ebola vaccination begins in North Kivu". ReliefWeb. Retrieved 9 August 2018.
  187. ^ "Ebola Virus Disease". World Health Organization. Retrieved January 29, 2019.
  188. ^ "Pregnant and lactating women should be vaccinated in an Ebola outbreak - STAT". STAT. 27 August 2018. Retrieved 2 September 2018.
  189. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Jeudi 16 août 2018". mailchi.mp. Retrieved 17 August 2018.
  190. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Vendredi 24 août 2018". mailchi.mp. Retrieved 24 August 2018.
  191. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Vendredi 26 octobre 2018". mailchi.mp. Retrieved 26 October 2018.
  192. ^ "As Ebola outbreak spreads in Congo, concern grows over vaccine supplies". STAT. 3 December 2018. Retrieved 4 December 2018.
  193. ^ "WHO | Deputy Director-General Dr Peter Salama, Deputy Director-General of Emergency Preparedness and Response". WHO. Retrieved 4 December 2018.
  194. ^ Mole, Beth (2019-04-16). "As Ebola outbreak rages, vaccine is 97.5% effective, protecting over 90K people". Ars Technica. Retrieved 2019-04-17.
  195. ^ "Ebola Ring Vaccination Results 12 April 2019" (PDF). www.who.int. 12 April 2019. Retrieved 17 April 2019.
  196. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Mardi 14 août 2018". mailchi.mp. Retrieved 14 August 2018.
  197. ^ "Human-derived Monoclonal Antibody for Treatment of Ebola Virus Infection | Office of Technology Transfer, NIH". www.ott.nih.gov. Retrieved 14 August 2018.
  198. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Mardi 18 septembre 2018". mailchi.mp. Retrieved 19 September 2018.
  199. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans la province du Nord Kivu au Lundi 20 août 2018". mailchi.mp. Retrieved 19 September 2018.
  200. ^ "Ebola virus disease – Democratic Republic of the Congo. Disease Outbreak News, 14 September 2018". who.int. Retrieved 19 September 2018.
  201. ^ "Emergencies preparedness, response" (PDF). World Health Organization. Retrieved 5 September 2018.
  202. ^ Burki, Talha Khan (July 2016). "Post-Ebola syndrome". The Lancet Infectious Diseases. 16 (7): 780–781. doi:10.1016/S1473-3099(15)00259-5. ISSN 1473-3099. PMID 27352759. Retrieved 2 September 2018.
  203. ^ "Ebola survivors returning home to fear, stigma in Congo". Washington Post. Retrieved 2 September 2018.
  204. ^ News, ABC. "Ebola survivors returning home to fear, stigma in Congo". ABC News. Retrieved 4 September 2018.
  205. ^ "DRC children deeply affected by Ebola outbreak - UNICEF | Africanews". Africanews. 2018-08-21. Retrieved 5 September 2018.
  206. ^ Carod-Artal, Francisco Javier (3 October 2015). "Post-Ebolavirus disease syndrome: what do we know?". Expert Review of Anti-infective Therapy. 13 (10): 1185–1187. doi:10.1586/14787210.2015.1079128. ISSN 1478-7210. PMID 26293407.
  207. ^ Scott, Janet T.; Sesay, Foday R.; Massaquoi, Thomas A.; Idriss, Baimba R.; Sahr, Foday; Semple, Malcolm G. (2016). "Post-Ebola Syndrome, Sierra Leone". Emerging Infectious Diseases. 22 (4): 641–646. doi:10.3201/eid2204.151302. ISSN 1080-6059. PMC 4806950. PMID 26983037.
  208. ^ Shears, P.; O'Dempsey, T.J.D. (May 2015). "Ebola virus disease in Africa: epidemiology and nosocomial transmission". Journal of Hospital Infection. 90 (1): 1–9. doi:10.1016/j.jhin.2015.01.002. PMID 25655197. Retrieved 25 August 2018.
  209. ^ Report of an International Commission (1978). "Ebola haemorrhagic fever in Zaire, 1976". Bulletin of the World Health Organization. 56 (2): 271–293. ISSN 0042-9686. PMC 2395567. PMID 307456.
  210. ^ Schlein, Lisa (15 August 2018). "West Africa: Ebola Outbreak Potentially More Dangerous Than West African Epidemic". Voice of America (Washington, DC). Retrieved 16 August 2018.
  211. ^ News, A. B. C. (29 August 2018). "Congo's latest Ebola outbreak could become 'worst ever' in East Africa, IRC warns". ABC News. Retrieved 30 August 2018.
  212. ^ Report of an International Commission (1978). "Ebola haemorrhagic fever in Zaire, 1976". Bulletin of the World Health Organization. 56 (2): 271–293. ISSN 0042-9686. PMC 2395567. PMID 307456.
  213. ^ a b c "Years of Ebola Virus Disease Outbreaks". www.cdc.gov. 18 May 2018. Retrieved 22 May 2018.
  214. ^ Heymann, D. L.; et al. (1980). "Ebola Hemorrhagic Fever: Tandala, Zaire, 1977–1978". Journal of Infectious Diseases. 142 (3): 372–76. doi:10.1093/infdis/142.3.372.
  215. ^ Khan, A. S.; Tshioko, F. K.; Heymann, D. L.; Le Guenno, B.; Nabeth, P.; Kerstiëns, B.; Fleerackers, Y.; Kilmarx, P. H.; Rodier, G. R.; Nkuku, O.; Rollin, P. E.; Sanchez, A.; Zaki, S. R.; Swanepoel, R.; Tomori, O.; Nichol, S. T.; Peters, C. J.; Muyembe-Tamfum, J. J.; Ksiazek, T. G. (1999). "The reemergence of Ebola hemorrhagic fever, Democratic Republic of the Congo, 1995. Commission de Lutte contre les Epidémies à Kikwit". The Journal of Infectious Diseases. 179 Suppl 1: S76–86. doi:10.1086/514306. ISSN 0022-1899. PMID 9988168.
  216. ^ "Outbreak news. Ebola virus haemorrhagic fever, Democratic Republic of the Congo--update". Releve Epidemiologique Hebdomadaire. 82 (40): 345–346. 5 October 2007. ISSN 0049-8114. PMID 17918654.
  217. ^ "WHO | End of Ebola outbreak in the Democratic Republic of the Congo". www.who.int. Retrieved 22 May 2018.
  218. ^ "Congo declares its Ebola outbreak over". Reuters. November 15, 2014. Retrieved 22 May 2018.
  219. ^ "Democratic Republic of the Congo Ebola virus" (PDF). World Health Organization. Retrieved 22 May 2018.
  220. ^ "Ebola virus disease – Democratic Republic of the Congo: Disease outbreak news, 25 July 2018". ReliefWeb. Retrieved 26 July 2018.
  221. ^ "Current Ebola outbreak is worst in Congo's history: Ministry". The Standard. Retrieved 10 November 2018.
  222. ^ "Outbreak Table | Marburg Hemorrhagic Fever | CDC". www.cdc.gov. Retrieved 10 October 2018.
  223. ^ "EBOLA RDC - Evolution de la riposte contre l'épidémie d'Ebola dans les provinces du Nord Kivu et de l'Ituri au Lundi 25 février 2019". us13.campaign-archive.com. Retrieved 25 February 2019.
  224. ^ Okware, S. I.; Omaswa, F. G.; Zaramba, S.; Opio, A.; Lutwama, J. J.; Kamugisha, J.; Rwaguma, E. B.; Kagwa, P.; Lamunu, M. (December 2002). "An outbreak of Ebola in Uganda". Tropical Medicine & International Health: TM & IH. 7 (12): 1068–1075. doi:10.1046/j.1365-3156.2002.00944.x. ISSN 1360-2276. PMID 12460399.
  225. ^ "Ebola data and statistics". WHO. Retrieved 5 November 2018.
  226. ^ Tedros Adhanom Ghebreyesus (12 April 2019). "IHR Emergency Committee on Ebola virus disease in the Democratic Republic of Congo, North Kivu". World Health Organization. Retrieved 13 April 2019.

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