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1981 in sports describes the year's events in world sport.
- January 25 – Super Bowl XV: the Oakland Raiders (AFC) won 27−10 over the Philadelphia Eagles (NFC)
- Sugar Bowl (1980 season):
- October 11 - LeRoy Irvin sets NFL record for most punt return yards in a game (207).
- UEFA Champions League – Liverpool FC 1-0 Real Madrid
- UEFA Cup – two leg final: 1st leg Ipswich Town F.C. 3-0 AZ '67 (Alkmaar); 2nd leg AZ '67 4-2 Ipswich Town. Ipswich Town win 5-4 on aggregate
- Cup Winners' Cup – Dynamo Tbilisi 2-1 Carl Zeiss Jena
- Copa Libertadores de América – Flamengo 2-0 Cobreloa
- World Club Championship – Flamengo 3-0 Liverpool FC
- Aston Villa win English League Championship
- FA Cup – Tottenham Hotspur win 3-2 over Manchester City
- Victorian Football League
- May 23 – A protest by Richmond against the eligibility of defender Doug Cox to play for St. Kilda led to the Saints temporarily losing the points for their first two wins. They were reinstated later due to changes in the relevant rules, but a fine of $5000 remained.
- June 6 – Richmond’s Kevin Bartlett became the first to play 350 VFL games.
- Carlton win the 85th VFL Premiership, beating Collingwood 12.20 (92) to 10.12 (72)
- Brownlow Medal awarded to Barry Round (South Melbourne) and Bernie Quinlan (Fitzroy)
- At the end of the season, South Melbourne relocate to Sydney and are renamed the Sydney Swans.
- For a Venezuelans baseball player's strike the Caribbean World Series of this year is cancelled.
- January 15 - In his first year of eligibility, former Cardinals pitcher Bob Gibson is the only player elected to the Baseball Hall of Fame. Gibson won 20 games five times, struck out 3,117 batters, and captured the Cy Young Award and MVP in 1968 with a 1.12 ERA. Players falling short of the 301 votes needed for election include Don Drysdale (243), Gil Hodges (241), Harmon Killebrew (239), Hoyt Wilhelm (238), and Juan Marichal (233). All except Hodges would subsequently gain election.
- April 18 - An International League game between the Pawtucket Red Sox and the visiting Rochester Red Wings set the record for the most innings ever played in a single professional baseball game, at 33 innings (24 extra innings). The game was suspended after 32 innings on the morning of April 19, and was concluded on June 23 with a 3-2 Pawtucket victory.
- June 12 - Major League Baseball players begin a 49-day strike over the issue of free-agent compensation.
- World Series – Los Angeles Dodgers win 4 games to 2 over the New York Yankees. The Series MVP is a tie between Ron Cey, Pedro Guerrero and Steve Yeager, Los Angeles
- April 11 – Larry Holmes defeats Trevor Berbick by a unanimous decision to retain the WBC heavyweight title.
- August 21 – Salvador Sánchez defeats Wilfredo Gómez by knockout in round eight to retain boxing's WBC world Featherweight title.(see: The Battle of the Little Giants)
- September 16 – Sugar Ray Leonard defeats Thomas Hearns by knockout in round 14 to unify boxing's world Welterweight title.
- October 3 – Mike Weaver defeats James (Quick) Tillis by a unanimous decision to retain the WBA heavyweight title. Marvin Hagler defeats Mustafa Hamsho by eleventh-round technical knockout to retain his undisputed world Middleweight title as Weaver-Tillis' show's main event.
- Gaelic football
- Ladies' Gaelic football
- Masters Tournament - Tom Watson
- U.S. Open - David Graham
- British Open - Bill Rogers
- PGA Championship - Larry Nelson
- PGA Tour money leader - Tom Kite - $375,699
- Senior PGA Tour money leader - Miller Barber - $83,136
- Ryder Cup - United States win 18½ to 9½ over Europe in team golf.
- United States Pacing Triple Crown races –
- United States Trotting Triple Crown races –
- Australian Inter Dominion Harness Racing Championship –
- Pacers: San Simeon
- August 30 – John Henry becomes the first horse to win a million dollar race, the inaugural Arlington Million, at Arlington Park in the Chicago suburb of Arlington Heights, Illinois.
- November – inaugural running of the Japan Cup, the most prestigious horse race in Japan, at Tokyo Racecourse in Fuchu, Tokyo. Its distance is about 1½ miles on turf and it is the world's richest turf race.
- Australia – Melbourne Cup won by Just A Dash
- Canada – Queen's Plate won by Fiddle Dancer Boy
- France – 1981 Prix de l'Arc de Triomphe won by Gold River
- Ireland – Irish Derby Stakes won by Shergar
- Japan – Japan Cup won by Mairzy Doates
- English Triple Crown Races:
- United States Triple Crown Races:
Quarter Horse Racing
- Triple Crown of Quarter Horse Racing
- Special Effort
- May 10 - Cornwall Royals defeat the Kitchener Rangers to win the 1981 Memorial Cup
- May 21 - New York Islanders defeat the Minnesota North Stars to win the 1981 Stanley Cup
- Ice Hockey World Championships:
- Men's champion: Soviet Union defeated Sweden
- Junior Men's champion: Sweden defeated Finland
- August 27 – death of Valeri Kharlamov (33), Russian player, in a car crash
- Grand Slam in tennis men's results:
- Grand Slam in tennis women's results:
- Davis Cup – United States wins 3-1 over Argentina in world tennis.
- "Epsom Derby | History, Winners, & Facts | Britannica". www.britannica.com. Retrieved 4 January 2022.