Talk:Biosensor

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Starting to have a fiddle with this. The applications edit is me, that's better but by no means exhaustive. I've also added a principles of detection section, it's basic but something to work on.Dwayne Dibly 00:21, 21 December 2005 (UTC)

I think the electronic nose link is wrong, I'm pretty sure the e-nose doesn't have any specific biological recognition elements. I'll leave it for now. Dwayne Dibly 00:21, 21 December 2005 (UTC) I think it's wrong too (biological sytems enginnering student).. I suspect that piezo based biosensors are not based on evanescent waves. Can anyone provide evidence that they are?

the electronic nose is based on electrical properties around an inorganic sensor. biosensors are specific because they an enzyme or other biological components. the e-nose on the other hand uses non-specific input often analysed with fuzzy logics or multivariate analysis. in short, an e-nose is not an biosensors. Benkeboy 11:14, 21 April 2006 (UTC)

piezoelectric based sensors are not based on evanescent waves because they are not optical. compare evanescent and evanescent wave. they are all about mechanical vibration. change in frequency and damping (evanescence?) depending on the amount of material that is adsorbed to the sensor and also viscoelastic properties and ability to bind water of the adsorbent. Benkeboy 11:14, 21 April 2006 (UTC)

piezoelectric sensors can be used with biological recognition, eg by binding antibodies on the sensor. antigens can bind and thus increase the mass (frequency shift) but also bind water or stretch out into the solution (damping).Benkeboy 11:14, 21 April 2006 (UTC)

I will edit this. I've already changed the definition to the correct form. I will also put right the rest when I get chance. The principles bit, in particular, is very muddled. There seems to be some confusion between optical and piezolelectric methods. The discussion of the transducer is also somewhat baffling. (User: Jeff Newman)

Added some additional applications relating to the use of SPR biosensorsArthurbagwaste 13:23, 13 March 2007 (UTC)

I added some info about the principle of an SPR biosensor. I notice that a previous edit had been deleted as spam, as it referred to a specific brandname of instrument. Is this really useful in this context? The IPR is strictly protected between these companies and each brand of sensor will usually have a unique mode of operation. The general descriptions are so complex and vague, that a specific description of a number of the major manufacturers sensors would probably be a lot easier to follow? Any thoughts on this?Arthurbagwaste 16:22, 13 March 2007 (UTC)

Biochemical

There is IUPAC definition of a biochemical biosensors at [1] (btw who removed the high light characters in the character box under the edit box?)Benkeboy (talk) 11:31, 23 January 2008 (UTC)

The link is dead. Let is rest in peace. chami 07:46, 13 January 2014 (UTC) — Preceding unsigned comment added by Ck.mitra (talk • contribs)

I think the optical biosensor part is nor general enough. there are other optical biosensors (e.g. based on waveguides etc.). Also the description is slightly confusing as in the Kretschmann configuration the light is not reflected from the gold side of teh chip but the light has to pass through the glass. —Preceding unsigned comment added by 193.197.72.74 (talk) 14:44, 5 September 2008 (UTC)

Ion Channel Switch

This section needs revision and preferably complete rewrite. What is written does not make sensechami 18:23, 10 September 2011 (UTC) — Preceding unsigned comment added by Ck.mitra (talk • contribs)

Biotransducer....

There is nothing bio in biotransducers. They are just good old regular transducers.

I suggest that you change biotransducer to transducer.

The job of a transducer is to convert a signal of one type into another signal of a different type.

  chami 06:19, 13 January 2014 (UTC)  — Preceding unsigned comment added by Ck.mitra (talk • contribs)  

gravimetric biosensors?

Never heard about a gravimetric biosensor before! One good example will be good enough.

You have missed thermal or thermometric biosensors. Mosbach wrote a chapter on them long ago.

The transducer characteristic must match with a corresponding change in a physical property as and when the analyte binds to the biorecognition element. In this sense, piezoelectric transducer is essentially a mass change transducer (same as SAW element).

chami 07:09, 13 January 2014 (UTC) — Preceding unsigned comment added by Ck.mitra (talk • contribs)

Placement of biosensors[edit]

I suspect this division is quasi-arbitrary and isn't coherent. This section needs significant editing/rewrite. — Preceding unsigned comment added by Srivatsaaithal (talk • contribs) 03:57, 31 March 2014 (UTC)

DNA Biosensor is Science Fiction

The whole section on DNA biosensors is, well, not wrong in the sense that it would indeed be great to have. But in reality there is currently no such thing as a DNA biosensor. Not surprisingly, there is no source given in the section. The whole section should be removed. If that hurts too much, then one could put it into a "possible future developments" section. — Preceding unsigned comment added by Graik (talk • contribs) 16:20, 24 January 2015 (UTC)

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"Label-Free and Ultrasensitive Electrochemical DNA Biosensor Based on Urchinlike Carbon Nanotube-Gold Nanoparticle Nanoclusters"

Label-Free and Ultrasensitive Electrochemical DNA Biosensor Based on Urchinlike Carbon Nanotube-Gold Nanoparticle Nanoclusters [2] [3]

Please add some short information about this to the section "DNA biosensors".

If it's relevant you could also add an entry for it to 2020 in science. That page is why I found reports about this paper.

--Prototyperspective (talk) 11:21, 15 May 2020 (UTC)

Please update with "Molecular electronics sensors on a scalable semiconductor chip: A platform for single-molecule measurement of binding kinetics and enzyme activity"

I think it would be good to add some brief info about this to the article. It's currently featured in 2022 in science like so:

A chip with molecular circuit components in single-molecule (bio)sensors is demonstrated.

There are also some news reports about it and here is a press release with relevant info/media.

References

Prototyperspective (talk) 15:13, 21 February 2022 (UTC)