Its history was dominated by the mills of the textile industry. Rawson's Mill on Old Lane is now disused and designated as a listed building of heritage importance.
Boothtown includes Akroydon, a Victorian model housing scheme which was designed in the Gothic style by George Gilbert Scott in 1859 for the workers at the mills of Edward Akroyd. Akroyd's former home in Boothtown, now the Grade II listed Bankfield Museum and library, also houses the Regimental museum of the Duke of Wellington's Regiment.
Boothtown is situated on the A647 road from Halifax to Bradford. It was on this road that Percy Shaw came up with the idea of cat's eyes as an aid to road safety. The longest running Boys' Brigade Company in Calderdale is based at Boothtown.
Boothtown is the home of Saint John the Baptist Serbian Orthodox church. There has been a Serbian community in the area since the 1940s, when Serbian POWs and anti-Communist refugees from German camps arrived in Halifax in 1947. They needed a place to worship and were given a former Methodist chapel in Simpson Street to worship in. Closed in the 1950s, it was acquired by the Serbian Orthodox Church in 1952. The building, by then in a dilapidated state, was renovated and consecrated on 26 September 1954.
- Historic England. "OLD LANE MILL RAWSON'S MILL (1244144)". National Heritage List for England. Retrieved 7 May 2018.
- Historic England. "BANKFIELD MUSEUM AND SCREEN WALL TO FORECOURT (1211183)". National Heritage List for England. Retrieved 10 January 2015.
- "History of St John the Baptist Orthodox Church Halifax". Official website. Retrieved 26 November 2014.