This is the Preliminary Round of the Copa Libertadores 2007 tournament. A total of 12 teams played in a two-legged round with 6 teams proceeding to the next round. Team 1 played the first leg at home. The away goals rule was employed in this round. The preliminary round was played between January 24 and February 7.
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
Blooming 
|
0–6 |  Santos
|
0–1 | 0–5 |
Vélez Sársfield 
|
5–1 |  Danubio
|
3–0 | 2–1 |
Deportivo Táchira 
|
1–4 |  Deportes Tolima
|
1–2 | 0–2 |
Tacuary 
|
1–4 |  LDU Quito
|
1–1 | 0–3 |
Cobreloa 
|
1–3 | Paraná Clube
|
0–2 | 1–1 |
América 
|
6–2 |  Sporting Cristal
|
5–0 | 1–2 |
Matches edit
First leg edit
| Vélez Sársfield | 3–0 | Danubio |
|---|---|---|
Zárate  13'Balvorín 48'Pellegrino 75' |
Report |
| Deportivo Táchira | 1–2 | Deportes Tolima |
|---|---|---|
| Morán 37' |
Report | Perlaza 44' Charría 75' (p) |
Second leg edit
| Santos | 5–0 | Blooming |
|---|---|---|
| Santana 2', 28' Rodrigo Tiuí 36', 83'Marcos Aurélio 76' |
Report |
Santos advanced on points 6–0.
Vélez Sarsfield advanced on points 4–2.
| Deportes Tolima | 2–0 | Deportivo Táchira |
|---|---|---|
| Savoia 19' Perlaza 67' |
Report |
Deportivo Tolima advanced on points 4–1.
LDU Quito advanced on points 4–1.
Parana advanced on points 3–1.
América advanced on points 6–2.