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|Ab urbe condita||2103|
|Balinese saka calendar||1271–1272|
|English Regnal year||23 Edw. 3 – 24 Edw. 3|
|Chinese calendar||己丑年 (Earth Ox)|
4046 or 3986
— to —
庚寅年 (Metal Tiger)
4047 or 3987
|- Vikram Samvat||1406–1407|
|- Shaka Samvat||1271–1272|
|- Kali Yuga||4450–4451|
|Japanese calendar||Jōwa 6 / Kannō 1|
|Minguo calendar||562 before ROC|
|Thai solar calendar||1892–1893|
1476 or 1095 or 323
— to —
1477 or 1096 or 324
|Wikimedia Commons has media related to 1350.|
- January 9 – Giovanni II Valente becomes Doge of Genoa.
- May 23 – A number of supporters of William V, Count of Holland, in his power struggle with his mother Margaret I, Countess of Holland, found the Cod League.
- August 29 – Battle of Les Espagnols sur Mer off Winchelsea: An English fleet personally commanded by King Edward III defeats a Castilian fleet.
- September 5 – Conservative noblemen in the County of Holland found the Hook League.
- September (unknown date) The first pestilence dies out.[clarification needed]
- November 17 – To pay for the expenses of the revived war with the Republic of Venice, the Republic of Genoa has to subscribe a loan at an interest rate of 10%, from an association of creditors known as the Compera imposita per gerra Venetorum.
- Hayam Wuruk becomes ruler of the Majapahit Empire.
- The Black Death first appears in Scotland.
- The castle of Rapperswil is largely destroyed by Rudolf Brun, mayor of the city of Zürich.
- The national law of Magnus Erikssons landslag is introduced in Sweden.
- January 23 – Vincent Ferrer, Valencian missionary and saint (d. 1419)
- April 13 – Margaret III, Countess of Flanders (d. 1405)
- June 27 – Manuel II Palaiologos, Byzantine Emperor (d. 1425)
- October 12 – Dmitri Donskoi, Grand Duke of Muscovy and Vladimir (d. 1389)
- November 25 – Katherine Swynford, mistress of John of Gaunt (approximate date; d. 1403)
- December 27 – John I of Aragon (d. 1396)
- date unknown
- Jehuda Cresques, Catalan cartographer (d. 1427)
- Agnolo Gaddi, Italian painter (d. 1396)
- William Gascoigne, Chief Justice of England (approximate date; d. 1419)
- Thomas Holland, 2nd Earl of Kent (d. 1397)
- John Montacute, 3rd Earl of Salisbury (approximate date; d. 1400)
- Madhava of Sangamagrama, Indian mathematician (d. 1425)
- John I Stanley of the Isle of Man (approximate date; d. 1414)
- Hrvoje Vukčić Hrvatinić (d. 1415)
- William le Scrope, 1st Earl of Wiltshire (d. 1399)
- Andrew of Wyntoun, Scottish historian (d. 1420)
- Záviš von Zap, Czech theologian and composer (d. c. 1411)
- January 6 – Giovanni I di Murta, second doge of the Republic of Genoa
- March 26 or 27 March – Alfonso XI of Castile (b. 1311)
- August 22 – Philip VI of France (b. 1293)
- November 19 – Raoul II of Brienne, Count of Eu
- December 26 – Jean de Marigny, French bishop
- date unknown – Maol Íosa V, Earl of Strathearn, last Gaelic Mormaer of Strathearn