Talk:Nancy Zahniser

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Yerfani.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 01:23, 18 January 2022 (UTC)

Sources for updating

Hi,

I plan to update this page with information from Dr. Zahniser's obituary as well as her most important work. Based on my research, here are sources that I plan to use for this project.

• "Nancy R. Zahniser, Ph.D." PhRMA Foundation. Retrieved 23 October 2016.
• "Obituary: Dr. Nancy Rutledge Zahniser". American Society for Pharmacology and Experimental Therapeutics. Retrieved 23 October 2016.
• Gulley, Joshua M; Hoover, Brian R; Larson, Gaynor A; Zahniser, Nancy R (25 June 2003). "Individual Differences in Cocaine-induced Locomotor Activity in Rats: Behavioral Characteristics, Cocaine Pharmacokinetics, and the Dopamine Transporter". Neuropsychopharmacology. doi:10.1038/sj.npp.1300279.
• Heard, Kennon; Palmer, Robert; Zahniser, Nancy R. (26 September 2008). "Mechanisms of Acute Cocaine Toxicity". The Open Pharmacology Journal. 2 (1): 70–78. doi:10.2174/1874143600802010070.
• Peris, Joanna; Zahniser, Nancy R. (1 January 1989). "Persistent augmented dopamine release after acute cocaine requires dopamine receptor activation". Pharmacology Biochemistry and Behavior. 32 (1): 71–76. doi:10.1016/0091-3057(89)90212-8. ISSN 0091-3057.
• Culver, Kirsten E.; Szechtman, Henry; Levant, Beth (September 2008). "Altered dopamine D2-like receptor binding in rats with behavioral sensitization to quinpirole: effects of pre-treatment with Ro 41-1049". European Journal of Pharmacology. 592 (1–3): 67–72. doi:10.1016/j.ejphar.2008.06.101.
• Zahniser, Nancy R.; Molinoff, Perry B. (05 October 1978). "Effect of guanine nucleotides on striatal dopamine receptors". Nature. 275: 453–455. doi:10.1038/275453a0. {{cite journal}}: Check date values in: |date= (help)
• Zahniser, N R; Chou, D; Hanin, I (March 1977). "Is 2-dimethylaminoethanol (deanol) indeed a precursor of brain acetylcholine? A gas chromatographic evaluation". Journal of Pharmacology and Experimental Therapeutics. 200 (3): 545–559. Retrieved 23 October 2016.

• Hi and welcome to WP. Thanks for looking up these sources. Before describing Zahniser's research, you should read WP:PRIMARY and try to avoid synthesis and original research. Thanks! --Randykitty (talk) 08:02, 25 October 2016 (UTC)
• Thank you for your feedback! I will be sure to keep original research more concise and descriptive rather than explaining in full depth all of her work. I have been researching her most important work (as noted in her obituary) and plan to update the page with more information from her obituary and briefly discuss her work. My plan for this update is outlined as follows:

General:

• Name, profession, biggest contributions to science
• Youth/education, transition into career
• Dates of significant events in career
• Best-known work (one-sentence summary) and organizations she was a part of

Early life and education:

• Birthplace/date, location, family
• High school, college, PhD
• Thesis (brain acetylcholine study – already inputted)
• First job and marriage
• Post-doc

University of Colorado:

• Hired by UCHSC Dept of Pharmacology, first as instructor
• Then became tenure track asst professor in 1981
• Became prof w/ full tenure in 1991
• Also worked in neuroscience program, med student training program at U CO SOM
• Vice-chair and acting chair of Dept of Pharmacology 2003-2006
• CUSOM associate dean for research education from 2007-2012
• Resource for persons applying for training grants, fellowships and career awards
• Directed:

1. NIAAA-supported postdoc training grant
2. NIGMS-funded predoctoral pharmacology training grant
3. ASPET-supported Summer Undergrad Research Fellowship program for underrepresented students

• Helped grad students and postdoc trainees advance careers in her lab

1. Mentored research projects of 9 thesis students
2. Mentored projects of 22 postdoc fellows
3. Together published over 150 papers, reviews, book chapters
4. Many students now run independent neuroscience labs

Involvement in Societies, Organizations and National Meetings:

• Funded by NIH since 1981
• Regular member of NIDA National Advisory Council
• Regular member of NIDA Intramural Research Program Board of Scientific Counselors
• Ad hoc member of other NSF (National Science Foundation) and NIH review panels
• EDITORIAL BOARDS:

1. Pharmacological Communications
2. CNS Neuroscience and Therapeutics
3. Journal of Neuroscience Methods

• Awards from NIDA (National Institute on Drug Abuse)

1. RCDA award
2. MERIT award
3. Senior Scientist award

• Society for Neurosciences, 1979-death
• 1984: Award in Excellence in Pharmacology/Toxicology (PhRMA Foundation)
• ASPET (American Society for Pharmacology and Experimental Therapeutics), 1982-death

1. In neuropharmacology division
2. Secretary-Treasurer, 2001-2002

• Fellow in Executive Leadership in Academic Medicine program for women, 2005-2006
• 2014: Award in Excellence in Pharmacology/Toxicology (PhRMA Foundation)

1. Honored for achievements in field of DA regulation in drug addiction

NATIONAL MEETINGS

• Organized and chaired Gordon Research Conference on Catecholamines
• Distinguished lecturer

1. Univ of CO
2. Univ of Pitt (2009: Distinguished Alumna Award from UPitt School of Pharm)
3. Loyola Univ
4. UT Health Science Center, San Antonio

• 2013: “Zahniser Addiction Symposium” held in her honor at Univ of FL Center for Addiction Research and Education
• Scientific advisory boards

1. UT Waggoner Center for Alcohol and Addiction Research
2. Oregon Health Sciences University Methamphetamine Abuse Research Center
3. Univ of Kentucky Center for Drug Abuse Research Translation

Research Discoveries:

• Dopamine-related studies

1. FIRST TO DEMONSTRATE: Guanine nucleotides affect DA receptor binding
2. Alteration of DA receptors/transporters by repeated cocaine exposure
3. New rat model based on response to cocaine
4. Characterization of tagged DA transporter in mice

Personal life and death:

• More family life, extracurricular activities
• Battle with neuroglioblastoma
• Death

Publications:

• Copied from CV

1. **should some of these be cut out? There are about 150. — Preceding unsigned comment added by Yerfani (talk • contribs) 17:21, 1 November 2016 (UTC)

• Well, that's quite a program! I do hope that you have reliable sources for all of this. I did some searching when I wrote this article and couldn't find much, scientists rarely are the subject of coverage in newspapers and magazines (unlike really important people such as football players! :-) --Randykitty (talk) 09:46, 2 November 2016 (UTC)

• This article is now mainly based on obituaries and Zahniser's own publications. Obituaries are rarely sources for unbiased information, although they can be used to source non-controversial information like where a person worked and such). Deducting what her research was about and what was important from a personal investigation of her publications comes very close (probably too close) to original research and synthesis... I appreciate the effort you are putting into this, but this is not necessarily an improvement. --Randykitty (talk) 10:57, 10 December 2016 (UTC)