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This article is kind of misleading. It's not completely correct. Glucosuria is defined as an excretion of glucose in the urine. Nothing more, nothing less. It is not necessarily caused by a decrease of plasma insulin. The mechanism is this: The SGLT1 and SGLT2 transporters in the proximal tubule of the nephron have a maximum amount of glucose that they can transport per unit time. Under normal conditions, the amount of glucose filtered into the tubules by the glomeruli is less than the transport maximum. There are two ways therefore to account for glucosuria. Either: 1) The level of plasma glucose is so high that more glucose is filtered into the tubules than the glucose transporters can transport (transport maximum exceeded), or 2) The transport maximum itself is lowered (i.e. NO rise in plasma glucose!!). In fact, the condition 'familial glucosuria' is an example of this. A defect in the SGLT1 transporter causes ineffective reabsorption of filtered glucose. Therefore you can have glucose in the urine WITHOUT a decrease in plasma insulin, and without a rise in plasma glucose.
If noone objects, I may rewrite this article when I have some spare time. Vihsadas 07:05, 24 March 2007 (UTC)
- Can someone post a picture of what it looks like when its urinated out? Just the end product in a clear cup or something, not someone in the act.
- Urine with "too much" sugar in it looks just like normal urine. "Too much" is not actually all that much sugar. WhatamIdoing (talk) 00:57, 12 August 2008 (UTC)
Images anybody? edit
This page could use a good nephron diagram. Actually, I think that the nephron page could use a better nephron diagram too. Anybody have a good diagram that could be used?Wawot1 (talk) 05:32, 10 March 2009 (UTC)