Isaac Wayne (1772 – October 25, 1852) was a member of the U.S. House of Representatives from Pennsylvania, son of General "Mad" Anthony Wayne, and grandson of Isaac Wayne.

Isaac Wayne
Member of the
U.S. House of Representatives
from Pennsylvania
In office
March 4, 1823 – March 3, 1825
Constituency4th district (1823-1825)
Personal details
Born1772 (1772)
Paoli, Province of Pennsylvania, British America
DiedOctober 25, 1852(1852-10-25) (aged 79–80)
Chester County, Pennsylvania, U.S.
Political partyFederalist Party
RelativesAnthony Wayne (father)
Isaac Wayne (grandfather)
Samuel Van Leer (uncle)
EducationDickinson College
Military service
Branch/serviceSeal of the United States Board of War and Ordnance.svg U.S. Army
Years of service1812-1823
RankUS-O6 insignia.svg Colonel
Battles/warsWar of 1812


Wayne was born in 1772[1] at Waynesborough, the family estate in Paoli in the Province of Pennsylvania. He graduated from Dickinson College in Carlisle, Pennsylvania, then studied law and was admitted to the Chester County, Pennsylvania, bar in 1795. He was a member of the Pennsylvania House of Representatives from 1799 to 1801 and 1806, and served in the Pennsylvania State Senate in 1810. During the War of 1812, Wayne was captain of a troop of Pennsylvania Horse Cavalry, raised and equipped by himself, and was subsequently colonel of the Second Regiment, Pennsylvania Volunteer Infantry.

In 1840, Wayne was elected as a member to the American Philosophical Society.[2]

Wayne unsuccessfully ran as a Federalist candidate for Governor in 1814, but was elected to the Eighteenth Congress. He died in Chester County on October 25, 1852. He is buried in the family plot at St. David's (Radnor) Episcopal Church in Radnor, Pennsylvania.


  1. ^ Anthony and Mary (Penrose) Wayne Family Bible
  2. ^ "APS Member History". Retrieved April 9, 2021.


Party political offices
Preceded by Federalist nominee for Governor of Pennsylvania
Succeeded by
U.S. House of Representatives
Preceded by Member of the U.S. House of Representatives
from Pennsylvania's 4th congressional district


alongside: James Buchanan and Samuel Edwards

Succeeded by