The Café's masters included, but are not limited to:
- In 1852 the café moved temporarily to hôtel Dodun, 21 Rue de Richelieu.
- In 1854 the Café de la Régence moved to 161 Rue Saint-Honoré and remained there until it became a restaurant in 1910.
- The chess players moved to the café de l'Univers in 1916.
- The Office national marocain du tourisme (National Moroccan Tourist Office) took over the site in 1918.
- The "great tournament of Paris 1867," won by Ignatz von Kolisch over Szymon Winawer and Wilhelm Steinitz, was played there.
- La Société des Amateurs was based there.
- In 1742, the celebrated French writers and philosophers Diderot and Rousseau met at this café.
- Karl Marx met Friedrich Engels for the second time at this café on 28 August 1844.
- According to the painter Oscar Parviainen, Jean Sibelius improvised the main theme, A Prayer to God, of the finale of his Third Symphony at Café de la Régence, in January 1906.
- The Norwegian painter Edvard Munch visited the café on 4 May 1885, during his first visit to France to study the French impressionists.
- Goldzink, Jean, XVIIIème siècle
- While at their first meeting, a few years before, they were not very impreased with each other, the meeting at the Paris cafe was the start of their lifelong personal and political association. Marx, Karl; Engels, Friedrich (1964-01-01). The Communist Manifesto. Pantheon Books – via Google Books.
- Ylirotu, Jeremias; et al. (Metropoli Oy (metropoli.fi)) (2002). "Ainolan ensimmäiset vuodet 1904-1908". www.sibelius.fi. Retrieved 2016-05-11.
- Prideaux, Sue (2005). Edvard Munch - Behind the Scream. Yale University Press. p. 27.
- Media related to Café de la Régence (Paris) at Wikimedia Commons