WD repeat and HMG-box DNA binding protein 1 is a protein in humans that is encoded by the WDHD1 gene. [5]

WDHD1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesWDHD1, AND-1, CHTF4, CTF4, AND1, WD repeat and HMG-box DNA binding protein 1, Ctf4
External IDsOMIM: 608126; MGI: 2443514; HomoloGene: 56019; GeneCards: WDHD1; OMA:WDHD1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001008396
NM_007086

NM_172598
NM_001360532

RefSeq (protein)

NP_001008397
NP_009017

NP_766186
NP_001347461

Location (UCSC)Chr 14: 54.94 – 55.03 MbChr 14: 47.48 – 47.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198554Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037572Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: WD repeat and HMG-box DNA binding protein 1". Retrieved 2013-02-18.

Further reading

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