Vaccine description | |
---|---|
Target | Japanese encephalitis |
Vaccine type | Killed/attenuated |
Clinical data | |
Trade names | Ixiaro, Imojev |
AHFS/Drugs.com | Monograph |
MedlinePlus | a607019 |
License data | |
Pregnancy category |
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Legal status | |
Legal status | |
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Japanese encephalitis vaccine is a vaccine that protects against Japanese encephalitis.[2] The vaccines are more than 90% effective.[2] The duration of protection with the vaccine is not clear but its effectiveness appears to decrease over time.[2] Doses are given either by injection into a muscle or just under the skin.[2]
It is recommended as part of routine immunizations in countries where the disease is a problem.[2] One or two doses are given depending on the version of the vaccine.[2] This should be completed at least a week before exposure.[3] Extra doses are not typically needed in areas where the disease is common.[2] Otherwise doses can be given after a year and after 10 years.[4] In those with HIV/AIDS or those who are pregnant an inactivated vaccine should be used.[2] Immunization of travellers who plan to spend time outdoors in areas where the disease is common is recommended.[2]
The vaccines are relatively safe.[2] Pain and redness may occur at the site of injection.[2] As of 2015[update], 15 different vaccines are available:[2] some are based on recombinant DNA techniques, others weakened virus, and others inactivated virus.[2]
The Japanese encephalitis vaccines first became available in the 1930s.[5] It is on the World Health Organization's List of Essential Medicines.[6] In the United States it costs between 100 and 200 USD for a course of immunizations.[7] In the UK it costs the NHS around £120 for a course, as of 2022.[4]
References
edit- ^ a b Use During Pregnancy and Breastfeeding
- ^ a b c d e f g h i j k l m World Health Organization (February 2015). "Japanese Encephalitis Vaccines: WHO position paper – February 2015". Weekly Epidemiological Record. 90 (9): 69–87. hdl:10665/242325. PMID 25726573.
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ignored (help) - ^ Prevatt, Natalie; Behrens, Ron H. (2021). "23. Paediatric vaccines for travel outside Europe". In Vesikari, Timo; Damme, Pierre Van (eds.). Pediatric Vaccines and Vaccinations: A European Textbook (Second ed.). Switzerland: Springer. pp. 270–271. ISBN 978-3-030-77172-0. Archived from the original on 5 February 2022. Retrieved 5 February 2022.
- ^ a b "14. Vaccines". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. p. 1390. ISBN 978-0-85711-413-6.
- ^ Paulke-Korinek, M; Kollaritsch, H (2008). "Japanese encephalitis and vaccines: past and future prospects". Wiener klinische Wochenschrift. 120 (19-20 Suppl 4): 15–9. doi:10.1007/s00508-008-1071-9. PMID 19066766.
Furthermore, vaccines against JEV have been available since the 1930s.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 315. ISBN 9781284057560.