British National Formulary
The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS). Information within the BNF includes indication(s), contraindications, side effects, doses, legal classification, names and prices of available proprietary and generic formulations, and any other notable points. Though it is a national formulary, it nevertheless also includes entries for some medicines which are not available under the NHS, and must be prescribed and/or purchased privately. A symbol clearly denotes such drugs in their entry.
The cover of BNF 73 (March 2017)
|Author||National Institute of Clinical Excellence|
|Genre||Clinical Pharmacy reference|
|Publisher||BMJ Group, and|
|September 2018 – 76th edition|
|Media type||Paperback print, digital online, smartphone app|
It is used by pharmacists and doctors (both general practitioners (GPs) and specialist practitioners), and by other prescribing healthcare professionals (such as nurses, pharmacy technicians, paramedics, and dentists); as a reference for correct dosage, indication, interactions and side effects of drugs. It is also used as a reassurance by those administering drugs, for example a nurse on a hospital ward, and even for patients and others seeking an authoritative source of advice on any aspect of pharmacotherapy.
The British Pharmacopoeia (BP) specifies quality standards for the making of drugs listed in the BNF.
Many individuals and organisations contribute towards the preparation of the BNF. It is jointly authored by the British Medical Association (BMA) and the Royal Pharmaceutical Society (RPS); and is jointly published by the BMJ Group (which is owned by the BMA), and the Pharmaceutical Press (owned by the Royal Pharmaceutical Society). It is published under the authority of a Joint Formulary Committee (JFC), which comprises representatives of the two professional bodies, and the Department of Health (DoH).
Information on drugs is drawn from the manufacturers' product literature, medical and pharmaceutical literature, regulatory authorities and professional bodies. Advice is constructed from clinical literature, and reflects, as far as possible, an evaluation of the evidence from diverse sources. The BNF also takes account of authoritative national guidelines and emerging safety concerns. In addition, the Joint Formulary Committee takes advice on all therapeutic areas from expert clinicians; this ensures that the BNF's recommendations are relevant to practice. However, in September 2013, the National Institute for Health and Care Excellence (NICE) in the UK opened a consultation on its draft decision not to give NICE accreditation to the processes to produce BNF publications following a review by an independent advisory committee.
It was first published in 1949 as the National Formulary, with updated versions appearing every three years until 1976. The fifth version in 1957 saw its name change to The British National Formulary. A new look version, under the auspices of Owen Wade, was released in 1981. A study in Northern Ireland looking at prescribing in 1965, reported that the BNF was likely able to serve the requirements of prescribers in general practice, while also achieving a cost saving. By 2003, issue 46 of the BNF contained 3000 interactions or groups of interactions, with about 900 of these marked by a bullet.
A new edition of the BNF book is published twice-yearly; in March and September. As of April 2020[update], the current edition is 79, which was published in March 2020. It is a customary tradition that the colour of each new edition is radically different from the previous.
The BNF is presently available as a book, a website, and mobile applications - the latter for use on smartphones and tablets. The book is available for purchase, and the September edition is distributed to healthcare professionals in the UK at no direct cost to them. NHS workers and healthcare professionals in the HINARI group of developing nations are entitled to free access via MedicinesComplete following registration (requires provision of a name, an address, an email address, and a phone number). Other visitors can subscribe to the BNF on MedicinesComplete. Healthcare organisations can also subscribe to a customisable BNF via their corporate online intranet. In June 2012, the National Institute for Health and Care Excellence (NICE) released applications for offline access to the BNF on iOS and Android devices. An NHS Athens log-in is required to use this application, and monthly content updates are available, over an internet connection. NICE also provides a website providing the content of the BNF to the public, including non-NHS users.
The British National Formulary for Children (BNFC) book, first published September 2005, is published yearly, and details the doses and uses of medicines in children from neonates to adolescents.
The Nurse Prescriber's Formulary for Community Practitioners (NPF) is issued in print every two years (September, odd-numbered years), for use by District Nurses and Specialist Community Public Health Nurses (including Health Visitors) who have received training to become nurse prescribers.
The British National Formulary is divided into various sections; with the main sections on drugs and preparations being organised by body system.
- Table of Contents
- How BNF publications are constructed
- How to use the BNF
- Guidance on prescribing
- Prescription writing
- Emergency supply of medicines
- Controlled drugs and drug dependence
- Adverse reactions to drugs
- Guidance on intravenous infusions
- Prescribing for children
- Prescribing in hepatic impairment
- Prescribing in renal impairment
- Prescribing in pregnancy
- Prescribing in breast-feeding
- Prescribing in palliative care
- Prescribing for the elderly
- Drugs and sport
- Prescribing in dental practice
- Notes on drugs and preparations
- Gastro-intestinal system
- Cardiovascular system
- Respiratory system
- Nervous system
- Endocrine system
- Genito-urinary system
- Malignant disease
- Blood and nutrition
- Musculoskeletal system
- Ear, nose, and oropharynx
- Emergency treatment of poisoning
- Appendices and indices
- Appendix 1 Interactions
- Appendix 2 Borderline substances
- Appendix 3 Cautionary and advisory labels for dispensed medicines
- Appendix 4 Wound management products and elasticated garments
- Dental Practitioners' Formulary
- Nurse Prescribers' Formulary
- Non-medical prescribing
- Index of proprietary manufacturers
- Special-order manufacturers
- "BNF Publications - Books". www.bnf.org. BMJ Group and Royal Pharmaceutical Society. Archived from the original on 17 August 2016. Retrieved 16 August 2016.
- "BNF Publications - About - Our organisation". www.bnf.org. BMJ Group and Royal Pharmaceutical Society. Archived from the original on 17 August 2016. Retrieved 16 August 2016.
- "NICE seeks views to inform BNF accreditation decision". www.nice.org.uk (Press release). National Institute for Health and Care Excellence. 6 September 2013. Archived from the original on 13 August 2014. Retrieved 19 July 2014.
- Anon (1957). "The British National Formulary". British Medical Journal. 2 (5047): 758–759. PMC 1962234. PMID 13460381.
- Wade, O. L. (1993). "British National Formulary: Its birth, death, and rebirth". BMJ (Clinical research ed.). 306 (6884): 1051–1054. doi:10.1136/bmj.306.6884.1051. PMC 1676980. PMID 8490505.
- Anon (1978). "British National Formulary 1976-8". British Medical Journal. 2 (6136): 580–581. doi:10.1136/bmj.2.6136.580-b. PMC 1606955. PMID 20792725.
- Wade, O. L.; McDevitt, G. D. (1966). "Prescribing and the British National Formulary". British Medical Journal. 2 (5514): 635–637. doi:10.1136/bmj.2.5514.635. PMC 1943465. PMID 20791099.
- Aronson, J. K. (2004). "Drug interactions-information, education, and the British National Formulary". British Journal of Clinical Pharmacology. 57 (4): 371–372. doi:10.1111/j.1365-2125.2004.02125.x. PMC 1884473. PMID 15025733.
- "Archived copy". Archived from the original on 1 October 2012. Retrieved 2012-06-14.CS1 maint: archived copy as title (link)
- "Archived copy". Archived from the original on 19 December 2008. Retrieved 22 December 2008.CS1 maint: archived copy as title (link) MedicinesComplete
- http://www.bnfformularycomplete.com Archived 25 September 2011 at the Wayback Machine BNF on FormularyComplete
- "NICE apps for smartphones and tablets". www.nice.org.uk. National Institute for Health and Care Excellence. April 2014. Archived from the original on 13 August 2014. Retrieved 19 July 2014.
- Elias-Jones, A.; Rylance, G. (2005). "The launch of the British National Formulary for Children". Archives of Disease in Childhood. 90 (10): 997–998. doi:10.1136/adc.2005.080366. PMC 1720111. PMID 16177154.
- "Archived copy". Archived from the original on 20 December 2007. Retrieved 2006-09-07.CS1 maint: archived copy as title (link) British National Formulary for Children
- "Products: Nurse Prescribers' Formulary". www.bnf.org. Archived from the original on 24 September 2014. Retrieved 19 July 2014.