 | |
 | |
| Clinical data | |
|---|---|
| Trade names | Lovenox, Clexane, Xaparin, others |
| Other names | Enoxaparin sodium |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a696006 |
| License data |
|
| Pregnancy category |
|
| Routes of administration | Subcutaneous (SC), intravenous (IV) |
| Legal status | |
| Legal status | |
| Pharmacokinetic data | |
| Elimination half-life | 4.5 hours |
| Chemical and physical data | |
| Formula | (C26H40N2O36S5)n |
| Molar mass | 4500 g/mol (average) |
  (what is this?) (verify) | |
Enoxaparin is an anticoagulant medication (blood thinner).[2] It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery.[2] It is also used in those with acute coronary syndrome (ACS) and heart attacks.[2] It is given by injection just under the skin or into a vein.[2] Other uses include inside kidney dialysis machines.[3]
Common side effects include bleeding, fever, and swelling of the legs.[2] Bleeding may be serious especially in those who are undergoing a spinal tap.[2] Use during pregnancy appears to be safe for the baby.[2] Enoxaparin is in the low molecular weight heparin family of medications.[2]
Enoxaparin was first made in 1981 and approved for medical use in 1993.[4][2] It is on the World Health Organization's List of Essential Medicines.[5] Enoxaparin is sold under several brand names and is available as a generic medication.[2] The wholesale cost in the developing world is about US$2–10 per day.[6] In the United States the wholesale cost is about $14 per day as of 2016.[7] Enoxaparin is made from heparin.[4] In 2017, it was the 299th most commonly prescribed medication in the United States, with more than one million prescriptions.[8][9] As of 2021, one pre-filled syringe of enoxaparin costs the NHS around £2-3.[10]
References
edit- ^ Cite error: The named reference
whowas invoked but never defined (see the help page). - ^ a b c d e f g h i j "Enoxaparin Sodium". The American Society of Health-System Pharmacists. Archived from the original on 21 December 2016. Retrieved 8 December 2016.
- ^ "Clexane Forte Syringes - Summary of Product Characteristics (SPC) - (eMC)". www.medicines.org.uk. 6 August 2015. Archived from the original on 20 December 2016. Retrieved 15 December 2016.
- ^ a b Network, Northern Neonatal (2008). Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life. John Wiley & Sons. p. 96. ISBN 9780470750353. Archived from the original on 2016-12-20.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "Enoxaparin". International Drug Price Indicator Guide. Archived from the original on 22 January 2018. Retrieved 8 December 2016.
- ^ "NADAC as of 2016-12-07 | Data.Medicaid.gov". Centers for Medicare and Medicaid Services. Archived from the original on 21 December 2016. Retrieved 15 December 2016.
- ^ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
- ^ "Enoxaparin Sodium - Drug Usage Statistics". ClinCalc. Archived from the original on 28 January 2020. Retrieved 11 April 2020.
- ^ "2. Cardiovascular system". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 142–143. ISBN 978-0-85711-413-6.
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