Talk:Morphine-6-glucuronide

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dihydromorphine-6-glucuronide edit

Latest comment: 14 years ago1 comment1 person in discussion

Apparently Dihydrocodeine (and potentially I am then assuming Dihydromorphine?) produces dihydromorphine-6-glucuronide as a metabolite that is 100 times more potent than itself. I assume the morphine M6G metabolite is by no measure that much more potent than morphine originally (it having to relate more to the dihydromorphine relative potency, if indeed DHM6G is a precursor to it as it's metabolite also), though that still seems like an excessive amount more. Alternate (morphine-semi-synthetic-variant)-6-glucuronides seem like an interesting venue. Nagelfar (talk) 14:40, 17 October 2009 (UTC)Reply

Is M6G more potent or less than morphine? edit

Latest comment: 6 years ago1 comment1 person in discussion

On the morphine wiki page, it states that M6G is half as potent as morphine itself, while this page states that it is more potent. Which is it? Both statements use the same article as justification: van Dorp EL, Romberg R, Sarton E, Bovill JG, Dahan A (2006). "Morphine-6-glucuronide: morphine's successor for postoperative pain relief?". Anesthesia and Analgesia. 102 (6): 1789–1797. — Preceding unsigned comment added by 2601:2C6:4E00:1109:8198:8B1A:E054:6BCF (talk) 22:37, 6 April 2018 (UTC)Reply

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