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what about the anaplerotic rxn of ornithine synthesis from glutamate?

should add it up


Ornithine does not affect the Citric Acid Cycle directly, it is not an intermediate. It shouldn't be considered an anaplerotic reaction.

Assessment comment

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The comment(s) below were originally left at Talk:Anaplerotic reactions/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

What about the reaction catalyzed by phosphoenol pyruvate carboxylase:

phosphoenol pyruvate + CO2 + GDP --> oxaloacetate + GTP

193.6.152.83 15:53, 19 June 2007 (UTC)Reply

Last edited at 15:53, 19 June 2007 (UTC). Substituted at 07:41, 29 April 2016 (UTC)

What about the anaplerotic reactions in other lifeforms?

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There are anaplerotic reactions that are not found in animals, such as the glyoxylate cycle. I think that they should probably be added to the page, or at least referred to. — Preceding unsigned comment added by 110.175.156.215 (talk) 04:45, 2 May 2016 (UTC)Reply

Wiki Education assignment: CHEM 378 - Biochemistry Lab

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  This article was the subject of a Wiki Education Foundation-supported course assignment, between 25 August 2022 and 15 December 2022. Further details are available on the course page. Student editor(s): Onishchoy (article contribs).

— Assignment last updated by Onishchoy (talk) 01:16, 3 November 2022 (UTC)Reply

Classification of aspartate transaminase reaction as anaplerotic per se?

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The conversion of aspartate to oxaloacetate via aspartate transaminase is listed as one of the five anaplerotic reactions. By itself, this is incomplete as the conversion requires alpha-ketoglutarate, a TCA cycle intermediate, although this is not mentioned in the table. The alpha-ketoglutarate must be regenerated from the glutamate produced, which requires the cooperation of a second enzyme, either glutamate dehydrogenase of another transaminase. This should be mentioned. Socialambulator (talk) 13:42, 23 December 2023 (UTC)Reply