Selenide, water dikinase

In enzymology, a selenide, water dikinase (EC 2.7.9.3) is an enzyme that catalyzes the chemical reaction

selenide, water dikinase
Identifiers
EC no.2.7.9.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
ATP + selenide + H2O AMP + selenophosphate + phosphate

The 3 substrates of this enzyme are ATP, selenide, and H2O, whereas its 3 products are AMP, selenophosphate, and phosphate.

This enzyme belongs to the family of transferases, to be specific, those transferring phosphorus-containing groups (phosphotransferases) with paired acceptors (dikinases). The systematic name of this enzyme class is ATP:selenide, water phosphotransferase. This enzyme is also called selenophosphate synthetase. This enzyme participates in selenoamino acid metabolism.

References

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  • Veres Z, Tsai L, Scholz TD, Politino M, Balaban RS, Stadtman TC (1992). "Synthesis of 5-methylaminomethyl-2-selenouridine in tRNAs: 31P NMR studies show the labile selenium donor synthesized by the selD gene product contains selenium bonded to phosphorus". Proc. Natl. Acad. Sci. U.S.A. 89 (7): 2975–9. Bibcode:1992PNAS...89.2975V. doi:10.1073/pnas.89.7.2975. PMC 48786. PMID 1557403.