April 12
- 1927 – An F5 tornado destroyed all but 12 buildings in Rocksprings, Texas, killing 72 people and injuring 205. Two others were killed outside of town.
- 1945 – A major tornado outbreak killed at least 118 people in the Midwestern and Southern United States. The worst of these was an F5 tornado that destroyed a large portion of Antlers, Oklahoma, killing 69 people. Despite the devastation, news of this event was largely overshadowed, even in local newspapers, by the death of President Franklin D. Roosevelt.