- May 31: In an unannounced vote, the Philadelphia City Council voted to evict the Cradle of Liberty Council Boy Scouts from the building they have occupied since 1928. (Philadelphia Inquirer)
- May 23: Mark J. Frisby becomes the publisher of the Philadelphia Daily News. (Philadelphia Inquirer)
- May 21: Former president of Independence Seaport Museum, John S. Carter, is charged with fraud and tax evasion for misappropriating more than US$1 million in funds from the museum. (Philadelphia Inquirer)
- May 15: Michael Nutter wins the Democratic primary nomination for the 2007 mayoral election. Republican Al Taubenberger ran unopposed. (Philadelphia Inquirer)