Knee replacement, also known as knee arthroplasty, is a surgical procedure to replace the weight-bearing surfaces of the knee joint to relieve pain and disability. It is most commonly performed for osteoarthritis, and also for other knee diseases such as rheumatoid arthritis and psoriatic arthritis. In patients with severe deformity from advanced rheumatoid arthritis, trauma, or long-standing osteoarthritis, the surgery may be more complicated and carry higher risk. Osteoporosis does not typically cause knee pain, deformity, or inflammation and is not a reason to perform knee replacement
|Other names||Knee arthroplasty|
Other major causes of debilitating pain include meniscus tears, cartilage defects, and ligament tears. Debilitating pain from osteoarthritis is much more common in the elderly.
Knee replacement surgery can be performed as a partial or a total knee replacement. In general, the surgery consists of replacing the diseased or damaged joint surfaces of the knee with metal and plastic components shaped to allow continued motion of the knee.
The operation typically involves substantial postoperative pain, and includes vigorous physical rehabilitation. The recovery period may be 12 weeks or longer and may involve the use of mobility aids (e.g. walking frames, canes, crutches) to enable the patient's return to preoperative mobility. It is estimated that approximately 82% of total knee replacements will last 25 years.
- 1 Medical uses
- 2 Pre-operative preparation
- 3 Technique
- 4 Variations
- 5 Components and zones
- 6 Risks
- 7 Post-operative evaluation
- 8 Post-operative rehabilitation
- 9 Frequency
- 10 See also
- 11 References
- 12 External links
Knee replacement surgery is most commonly performed in people with advanced osteoarthritis and should be considered when conservative treatments have been exhausted. Total knee replacement is also an option to correct significant knee joint or bone trauma in young patients. Similarly, total knee replacement can be performed to correct mild valgus or varus deformity. Serious valgus or varus deformity should be corrected by osteotomy. Physical therapy has been shown to improve function and may delay or prevent the need for knee replacement. Pain is often noted when performing physical activities requiring a wide range of motion in the knee joint.
|Angles commonly measured before knee replacement surgery:|
To indicate knee replacement in case of osteoarthritis, its radiographic classification and severity of symptoms should both be substantial. Such radiography should consist of weightbearing X-rays of both knees- AP, Lateral, and 30 degrees of flexion. AP and lateral views may not show joint space narrowing, but the 30 degree flexion view is most sensitive for narrowing. Full length projections are also used in order to adjust the prosthesis to provide a neutral angle for the distal lower extremity. Two angles used for this purpose are:
- Hip-knee-shaft angle (HKS), an angle formed between a line through the longitudinal axis of the femoral shaft and its mechanical axis, which is a line from the center of the femoral head to the intercondylar notch of the distal femur.
- Hip-knee-ankle angle (HKA), which is an angle between the femoral mechanical axis and the center of the ankle joint. It is normally between 1.0° and 1.5° of varus in adults.
The patient is to perform range of motion exercises and hip, knee and ankle strengthening as directed daily. Before the surgery is performed, pre-operative tests are done: usually a complete blood count, electrolytes, APTT and PT to measure blood clotting, chest X-rays, ECG, and blood cross-matching for possible transfusion. About a month before the surgery, the patient may be prescribed supplemental iron to boost the hemoglobin in their blood system. Accurate X-rays of the affected knee are needed to measure the size of components which will be needed. Medications such as warfarin and aspirin will be stopped some days before surgery to reduce the amount of bleeding. Patients may be admitted on the day of surgery if the pre-op work-up is done in the pre-anesthetic clinic or may come into hospital one or more days before surgery. Currently there is insufficient quality evidence to support the use of pre-operative physiotherapy in older adults undergoing total knee arthroplasty.
Preoperative education is currently an important part of patient care. There is some evidence that it may slightly reduce anxiety before knee replacement surgery, with low risk of detrimental effects.
The surgery involves exposure of the front of the knee, with detachment of part of the quadriceps muscle (vastus medialis) from the patella. The patella is displaced to one side of the joint, allowing exposure of the distal end of the femur and the proximal end of the tibia. The ends of these bones are then accurately cut to shape using cutting guides oriented to the long axis of the bones. The cartilages and the anterior cruciate ligament are removed; the posterior cruciate ligament may also be removed but the tibial and fibular collateral ligaments are preserved. Whether the posterior cruciate ligament is removed or preserved depends on the type of implant used, although there appears to be no clear difference in knee function or range of motion favouring either approach. Metal components are then impacted onto the bone or fixed using polymethylmethacrylate (PMMA) cement. Alternative techniques exist that affix the implant without cement. These cement-less techniques may involve osseointegration, including porous metal prostheses. Finally, stability and range of motion is checked, followed by irrigation, hemostasis, placement of hemovacs, and closure.
A round ended implant is used for the femur, mimicking the natural shape of the joint. On the tibia the component is flat, although it sometimes has a stem which goes down inside the bone for further stability. A flattened or slightly dished high-density polyethylene surface is then inserted onto the tibial component so that the weight is transferred metal to plastic not metal to metal. During the operation any deformities must be corrected, and the ligaments balanced so that the knee has a good range of movement and is stable and aligned. In some cases the articular surface of the patella is also removed and replaced by a polyethylene button cemented to the posterior surface of the patella. In other cases, the patella is replaced unaltered.
Post-operative pain controlEdit
The regional analgesia techniques (neuraxial anesthesia or continuous femoral nerve block or adductor canal block) are used most commonly. Local anesthesia infiltration in the pericapsular area using liposomal bupivacaine provides good analgesia in the post-operative period without increasing the risk for instability or nerve injury. A combined approach of local infiltration analgesia and femoral nerve block to achieve multimodal analgesia is common.
Variations in manufacture and surgical preparation for knee replacement occur between cemented and uncemented components, between resurfacing the patella or not, and between denervating the patella using electrocautery or not. Cemented-fixation may be more vulnerable to future aseptic loosening than the cement-less technique.
Retaining the posterior cruciate ligament (PCL) has been shown to be beneficial for patients. Removal of the PCL has been shown to reduce the maximal force that the individual can place on that knee. Typically individuals who have the PCL removed will lean forward while climbing in order to maximize the force of the quadriceps. A variation in the total knee replacement procedure is to permit movement in the prostheses using a polyethylene insert, an approach called a mobile bearing total knee arthroplasty. There is no strong evidence that this approach improves knee function, mortality, number of adverse effects, or amount of pain compared to a fixed bearing approach for total knee replacement that retains the PCL.
Minimally invasive procedures have been developed in total knee replacement that do not cut the quadriceps tendon. There are different definitions of minimally invasive knee surgery, which may include a shorter incision length, retraction of the patella without eversion (rotating out), and specialized instruments. There are few randomized trials, but studies have found less postoperative pain, shorter hospital stays, and shorter recovery. However, no studies have shown long-term benefits.
Partial knee replacementEdit
Unicompartmental arthroplasty (UKA), also called partial knee replacement, is an option for some people. The knee is generally divided into three "compartments": medial, lateral, and patellofemoral. Most people with arthritis severe enough to consider knee replacement have significant wear in two or more of the above compartments, and are treated with total knee replacement (TKA). A minority of people with osteoarthritis have wear primarily in one compartment, usually the medial, and may be candidates for unicompartmental knee replacement. Advantages of UKA compared to TKA include smaller incision, easier post-op rehabilitation, better postoperative range of motion, shorter hospital stay, less blood loss, lower risk of infection, stiffness, and blood clots, but a harder revision if necessary. Persons with infectious or inflammatory arthritis (rheumatoid arthritis, lupus, psoriasis), or marked deformity are not candidates for this procedure.
Components and zonesEdit
Standardized zones around the components are used for specifying for example signs of loosening on radiographic follow-up. There are various classification systems for specifying such zones, including by KS (Knee Society) zones published in 2015.
KS zones, anteroposterior (AP) view.
Specific KS zones are as follows, with * meaning that the zone can be specified as "A" (anterior), "P" (posterior), "M" (medial) or "L" (lateral):
- Femoral component (lateral view)
- Zone 1 and 2: Anterior and posterior flange, respectively.
- Zone 3: Central box/distal fixation region, where "A" and "P" designate the respective chamfers if visible*
- Zone 4: Stem extension*
- Zone 5: Stem
- Tibial component:
- Zone 1: Anterior on lateral view, medial on anteroposterior (AP) view.
- Zone 2: Posterior on lateral view, lateral on AP view.
- Zone 3: Central keel/stem/peg fixation region*
- Zone 4: Stem extension*
- Zone 5: Inferior aspect of keel or stem
Risks and complications in knee replacement are similar to those associated with all joint replacements. The most serious complication is infection of the joint, which occurs in <1% of patients. Risk factors for infection are related to both patient and surgical factors. Deep vein thrombosis occurs in up to 15% of patients, and is symptomatic in 2–3%. Nerve injuries occur in 1–2% of patients. Persistent pain or stiffness occurs in 8–23% of patients. Prosthesis failure occurs in approximately 2% of patients at 5 years.
There is increased risk of complications for obese people going through total knee replacement. The morbidly obese should be advised to lose weight before surgery and, if medically eligible, would probably benefit from bariatric surgery.
Fracturing or chipping of the polyethylene platform between the femoral and tibial components may be of concern. These fragments may become lodged in the knee and create pain or may move to other parts of the body. Advancements in implant design have greatly reduced these issues but the potential for concern is still present over the lifespan of the knee replacement.
Deep vein thrombosisEdit
According to the American Academy of Orthopedic Surgeons (AAOS), deep vein thrombosis in the leg is "the most common complication of knee replacement surgery... prevention... may include periodic elevation of patient's legs, lower leg exercises to increase circulation, support stockings and medication to thin your blood."
Periprosthetic fractures are becoming more frequent with the aging patient population and can occur intraoperatively or postoperatively. Depending on the location of the fracture and the stability of the prosthesis, these can be treated surgically with open reduction and internal fixation or revision of the prosthesis.
Loss of motionEdit
The knee at times may not recover its normal range of motion (0–135 degrees usually) after total knee replacement. Much of this is dependent on pre-operative function. Most patients can achieve 0–110 degrees, but stiffness of the joint can occur. In some situations, manipulation of the knee under anesthetic is used to reduce post operative stiffness. There are also many implants from manufacturers that are designed to be "high-flex" knees, offering a greater range of motion.
In some patients, the kneecap dislocates to the outer side of the knee after surgery. This is painful and usually needs to be treated by surgery to realign the kneecap. However, this is quite rare.
The current classification of AAOS divides prosthetic infections into four types.
- Type 1 (positive intraoperative culture): Two positive intraoperative cultures
- Type 2 (early postoperative infection): Infection occurring within first month after surgery
- Type 3 (acute hematogenous infection): Hematogenous seeding of site of previously well-functioning prosthesis
- Type 4 (late chronic infection): Chronic indolent clinical course; infection present for more than a month
While it is relatively rare, periprosthetic infection remains one of the most challenging complications of joint arthroplasty. A detailed clinical history and physical remain the most reliable tool to recognize a potential periprosthetic infection. In some cases the classic signs of fever, chills, painful joint, and a draining sinus may be present, and diagnostic studies are simply done to confirm the diagnosis. In reality though, most patients do not present with those clinical signs, and in fact the clinical presentation may overlap with other complications such as aseptic loosening and pain. In those cases diagnostic tests can be useful in confirming or excluding infection.
Modern diagnosis of infection around a total knee replacement is based on the Musculoskeletal Infection Society (MSIS) criteria. They are:
1.There is a sinus tract communicating with the prosthesis; or 2. A pathogen is isolated by culture from at least two separate tissue or fluid samples obtained from the affected prosthetic joint; or
Four of the following six criteria exist:
1.Elevated serum erythrocyte sedimentation rate (ESR>30mm/hr) and serum C-reactive protein (CRP>10 mg/L) concentration,
2.Elevated synovial leukocyte count,
3.Elevated synovial neutrophil percentage (PMN%),
4.Presence of purulence in the affected joint,
5.Isolation of a microorganism in one culture of periprosthetic tissue or fluid, or
6.Greater than five neutrophils per high-power field in five high-power fields observed from histologic analysis of periprosthetic tissue at ×400 magnification.
None of the above laboratory tests has 100% sensitivity or specificity for diagnosing infection. Specificity improves when the tests are performed in patients in whom clinical suspicion exists. ESR and CRP remain good 1st line tests for screening (high sensitivity, low specificity). Aspiration of the joint remains the test with the highest specificity for confirming infection.
The choice of treatment depends on the type of prosthetic infection.
- Positive intraoperative cultures: Antibiotic therapy alone
- Early post-operative infections: debridement, antibiotics, and retention of prosthesis.
- Acute hematogenous infections: debridement, antibiotic therapy, retention of prosthesis.
- Late chronic: delayed exchange arthroplasty. Surgical débridement and parenteral antibiotics alone in this group has limited success, and standard of care involves exchange arthroplasty.
Appropriate antibiotic doses can be found at the following instructional course lecture by AAOS
Knee replacement is routinely evaluated by X-ray, including the following measures:
- FFC: frontal femoral component angle. It is typically regarded as optimal when being 2–7° in valgus.
- FTC: frontal tibial component angle, which is regarded as optimal when being at a right angle. A varus position of more than 3° has generally been found to increase the failure rate of the prosthesis.
- Anterior femoral notching (the femoral component causing reduced thickness of the distal femur anteriorly), seems to cause an increased risk of fractures when exceeding about 3 mm.
- LTC: lateral (or sagittal) tibial component angle, which is ideally positioned so that the tibia is 0–7° flexed compared to at a right angle with the tibial plate.
The length of post-operative hospitalization is 5 days on average depending on the health status of the patient and the amount of support available outside the hospital setting. Protected weight bearing on crutches or a walker is required until specified by the surgeon because of weakness in the quadriceps muscle In the immediate post-operative period, up to 39% of knee replacement patients experience inadequate pain control.
To increase the likelihood of a good outcome after surgery, multiple weeks of physical therapy is necessary. In these weeks, the therapist will help the patient return to normal activities, as well as prevent blood clots, improve circulation, increase range of motion, and eventually strengthen the surrounding muscles through specific exercises. Whether techniques such as neuromuscular electrical stimulation are effective at promoting gains in knee muscle strength after surgery are unclear. Often range of motion (to the limits of the prosthesis) is recovered over the first two weeks (the earlier the better). Over time, patients are able to increase the amount of weight bearing on the operated leg, and eventually are able to tolerate full weight bearing with the guidance of the physical therapist. After about ten months, the patient should be able to return to normal daily activities, although the operated leg may be significantly weaker than the non-operated leg.
For post-operative knee replacement patients, immobility is a factor precipitated by pain and other complications. Mobility is known as an important aspect of human biology that has many beneficial effects on the body system. It is well documented in literature that physical immobility affects every body system and contributes to functional complications of prolonged illness. In most medical-surgical hospital units that perform knee replacements, ambulation is a key aspect of nursing care that is promoted to patients. Early ambulation can decrease the risk of complications associated with immobilization such as pressure ulcers, deep vein thrombosis (DVT), impaired pulmonary function, and loss of functional mobility. Nurses’ promotion and execution of early ambulation on patients has found that it greatly reduces the complications listed above, as well as decreases length of stay and costs associated with further hospitalization. Nurses may also work with teams such as physical therapy and occupational therapy to accomplish ambulation goals and reduce complications.
Continuous passive motion (CPM) is a postoperative therapy approach that uses a machine to move the knee continuously through a specific range of motion, with the goal of preventing joint stiffness and improving recovery. There is no evidence that CPM therapy leads to a clinically significant improvement in range of motion, pain, knee function, or quality of life. CPM is inexpensive, convenient, and assists patients in therapeutic compliance. However, CPM should be used in conjunction with traditional physical therapy. In unusual cases where the person has a problem which prevents standard mobilization treatment, then CPM may be useful.
Cryotherapy, also known as 'cold therapy' is sometimes recommended after surgery for pain relief and to limit swelling of the knee. Cryotherapy involves the application of ice bags or cooled water to the skin of the knee joint. However, the evidence that cryotherapy reduces pain and swelling is very weak and the benefits after total knee replacement surgery have been shown to be very small.
Some physicians and patients may consider having ultrasonography for deep venous thrombosis after knee replacement. However, this kind of screening should be done only when indicated because to perform it routinely would be unnecessary health care. If a medical condition exists that could cause deep vein thrombosis, a physician can choose to treat patients with cryotherapy and intermittent pneumatic compression as a preventive measure.
Neither gabapentin nor pregabalin have been found to be useful for pain following a knee replacement. A Cochrane review concluded that early multidisciplinary rehabilitation programs may produce better results at the rate of activity and participation.
With 718,000 hospitalizations, knee arthroplasty accounted for 4.6% of all United States operating room procedures in 2011—making it one of the most common procedures performed during hospital stays. The number of knee arthroplasty procedures performed in U.S. hospitals increased 93% between 2001 and 2011. A study of United States community hospitals showed that in 2012, among hospitalizations that involved an OR procedure, knee arthroplasty was the OR procedure performed most frequently during hospital stays paid by Medicare (10.8 percent of stays) and by private insurance (9.1 percent). Knee arthroplasty was not among the top five most frequently performed OR procedures for stays paid by Medicaid or for uninsured stays.
By 2030, the demand for primary total knee arthroplasty is projected to increase to 3.48 million surgeries performed annually in the U.S.
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