Isoflavone 7-O-glucosyltransferase

In enzymology, an isoflavone 7-O-glucosyltransferase (EC 2.4.1.170) is an enzyme that catalyzes the chemical reaction

isoflavone 7-O-glucosyltransferase
Identifiers
EC no.2.4.1.170
CAS no.97089-62-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
UDP-glucose + an isoflavone UDP + an isoflavone 7-O-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and isoflavone, whereas its two products are UDP and isoflavone 7-O-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase, UDPglucose-favonoid 7-O-glucosyltransferase, and UDPglucose:isoflavone 7-O-glucosyltransferase. This enzyme participates in isoflavonoid biosynthesis.

References

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  • Koster J, Barz W (1981). "UDP-glucose:isoflavone 7-O-glucosyltransferase from roots of chick pea (Cicer arietinum L.)". Arch. Biochem. Biophys. 212 (1): 98–104. doi:10.1016/0003-9861(81)90347-7. PMID 6458246.