Histone H2B type 3-B is a protein that in humans is encoded by the HIST3H2BB gene .[ 5] [ 6]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes . Nucleosomes consist of approximately 146 base pairs (bp) of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A , H2B , H3 , and H4 ). The chromatin fiber is further compacted through the interaction of a linker histone, H1 , with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.[ 6]
^ a b c ENSG00000285449 GRCh38: Ensembl release 89: ENSG00000196890, ENSG00000285449 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000080712 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics . 80 (5): 487–98. doi :10.1016/S0888-7543(02)96850-3 . PMID 12408966 . ^ a b "Entrez Gene: HIST3H2BB histone cluster 3, H2bb" .
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