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Gulf of Guacanayabo is located in Cuba
Gulf of Guacanayabo
Location of Gulf of Guacanayabo in Cuba
Gulf of Guacanayabo seen from space

The Gulf of Guacanayabo (Spanish: Golfo de Guacanayabo) is a bay along the southern coast of Cuba, bordered by Granma and Las Tunas provinces.


The largest port on the bay is Manzanillo, and the gulf is bordered to the north-west by the Jardines de la Reina archipelago. Cuba's longest river, the Cauto River, empties in the Gulf of Guacanayabo.

It is also where, in 2005, Hurricane Dennis had its peak effect.