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Guillaume François Rouelle (15 September 1703 – 3 August 1770)[1] was a French chemist and apothecary. In 1754 he introduced the concept of a base into chemistry, as a substance which reacts with an acid to give it solid form (as a salt).

Guillaume-François Rouelle
Guillaume-François Rouelle.jpg
Guillaume-François Rouelle
Born15 September 1703
Died3 August 1770 (aged 66)
Known forBase
Scientific career
InfluencedDenis Diderot
Antoine-Laurent de Lavoisier
Joseph Proust
Antoine-Augustin Parmentier

He is known as l'Aîné (the elder) to distinguish him from his younger brother, Hilaire Rouelle, who was also a chemist and known as the discoverer of urea.

He started a public course in his laboratory in 1738 where he taught many students among whom were Denis Diderot, Antoine-Laurent de Lavoisier, Joseph Proust and Antoine-Augustin Parmentier.

He was elected a foreign member of the Royal Swedish Academy of Sciences in 1749.


  1. ^ Dorveaux, Paul (1933). "Apothicaires membres de l'Académie Royale des sciences : IX. Guillaume-François Rouelle". Revue d'Histoire de la Pharmacie (in French). 84 (December): 169–186. Retrieved 24 March 2019.

Further readingEdit

  • Franckowiak, Rémi (2003). "Rouelle, un vrai-faux anti-newtonien". Archives internationales d'histoire des sciences. 53 (150–151): 240–255.
  • Franckowiak, Rémi (2002). "Les sels neutres de Guillaume-François Rouelle". Revue d'Histoire des Sciences. 55 (4): 493–532.
  • Jensen, William B. (2006). "The origin of the term "base"". The Journal of Chemical Education. 83 (8): 1130. Bibcode:2006JChEd..83.1130J. doi:10.1021/ed083p1130.
  • Lemay, Pierre; Oesper, Ralph E. (1954). "The lectures of Guillaume Francois Rouelle". The Journal of Chemical Education. 31 (7): 338. Bibcode:1954JChEd..31..338L. doi:10.1021/ed031p338.
  • Warolin, C. (1996). "Lavoisier". Histoire des sciences médicales. 30 (1): 30. PMID 11624829.
  • Warolin, C. (1995). "Lavoisier". Revue d'histoire de la pharmacie. 42 (307): 361–367. PMID 11624913.