The fourteen bones that form the human facial skeleton.
|Part of||Face, skeleton|
|Latin||ossa faciei, ossa facialia|
|Anatomical terms of bone|
- Inferior nasal concha (2)
- Lacrimal bones (2)
- Maxilla (2)
- Nasal bones (2)
- Palatine bones (2)
- Zygomatic bones (2)
Elements of the cartilaginous viscerocranium (i.e., splanchnocranial elements), such as the hyoid bone, are sometimes considered part of the facial skeleton. The ethmoid bone (or a part of it) and also the sphenoid bone are sometimes included, but otherwise considered part of the neurocranium. Because the maxillary bones are fused, they are often collectively listed as only one bone. The mandible is generally considered separately from the cranium.
The facial skeleton is composed of dermal bone and derived from the neural crest cells (also responsible for the development of the neurocranium, teeth and adrenal medulla) or from the sclerotome, which derives from the somite block of the mesoderm. As with the neurocranium, in Chondricthyes and other cartilaginous vertebrates, they are not replaced via endochondral ossification.
Variation in craniofacial form between humans is largely due to differing patterns of biological inheritance. Cross-analysis of osteological variables and genome-wide SNPs has identified specific genes that control this craniofacial development. Of these genes, DCHS2, RUNX2, GLI3, PAX1 and PAX3 were found to determine nasal morphology, whereas EDAR impacts chin protrusion.
Facial bones and neurocranium (labeled as "Brain case").
- Jinkins, J. Randy (2000). Atlas of Neuroradiologic Embryology, Anatomy, and Variants. Lippincott Williams & Wilkins. p. 458. ISBN 0781716527. Retrieved 24 August 2017.
- "Divisions of the Skeleton". U.S. National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program. Archived from the original on 14 January 2009. Retrieved 24 August 2017.CS1 maint: BOT: original-url status unknown (link)
- Adhikari, K., Fuentes-Guajardo, M., Quinto-Sánchez, M., Mendoza-Revilla, J., Chacón-Duque, J. C., Acuña-Alonzo, V., Gómez-Valdés, J. (2016). "A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation". Nature Communications. 7: 11616. doi:10.1038/ncomms11616. PMC 4874031. Retrieved 20 October 2016.CS1 maint: uses authors parameter (link)