D-arabinitol 4-dehydrogenase

In enzymology, a D-arabinitol 4-dehydrogenase (EC 1.1.1.11) is an enzyme that catalyzes the chemical reaction

D-arabitol 4-dehydrogenase
Identifiers
EC no.1.1.1.11
CAS no.9028-18-6
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
D-arabinitol + NAD+ D-xylulose + NADH + H+

Thus, the two substrates of this enzyme are D-arabinitol and NAD+, whereas its 3 products are D-xylulose, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-arabinitol:NAD+ 4-oxidoreductase. Other names in common use include D-arabitol dehydrogenase and arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.

References

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  • Characterization of Arabitol Dehyrogenase in Transplastomic Plants. LAP Lambert Academic Publishing. ISBN 978-3-659-49235-8
  • Lin ECC (1961). "An inducible D-arabitol dehydrogenase from Aerobacter aerogenes". J. Biol. Chem. 236: 31–36. PMID 13762204.
  • Wood WA, McDonough MJ, Jacobs LB (1961). "Ribitol and D-arabitol utilization by Aerobacter aerogenes". J. Biol. Chem. 236: 2190–2195.