Citramalate CoA-transferase

In enzymology, a citramalate CoA-transferase (EC 2.8.3.11) is an enzyme that catalyzes the chemical reaction

citramalate CoA-transferase
Identifiers
EC no.2.8.3.11
CAS no.9033-60-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
acetyl-CoA + citramalate acetate + (3S)-citramalyl-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and citramalate, whereas its two products are acetate and (3S)-citramalyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:citramalate CoA-transferase. This enzyme participates in c5-branched dibasic acid metabolism.

References

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  • Dimroth P, Buckel W, Loyal R, Eggerer H (1977). "Isolation and function of the subunits of citramalate lyase and formation of hybrids with the subunits of citrate lyase". Eur. J. Biochem. 80 (2): 469–77. doi:10.1111/j.1432-1033.1977.tb11902.x. PMID 923590.