Arnaldo Cantani, also known as Arnoldo Cantani (15 February 1837 – 1893) was an Italian physician and writer best known for his research on diabetes.
Arnaldo Cantani | |
|---|---|
 | |
| Born | 15 February 1837 Hainsbach, North Bohemia |
| Died | 1893 Naples, Italy |
| Occupation(s) | Physician, writer |
Biography edit
Cantani was born in Hainsbach, North Bohemia.[1] He entered to study medicine at the University of Prague in 1855 and obtained his M.D. in 1860. In 1864, the Italian Government offered Cantani the Chair of Materia Medica and Toxicology at the University of Pavia.[1] In 1867, he won by competition the position of head physician at the Medical Clinic at the Ospedale Maggiore in Milan.[1]
In 1868, he became Professor of Clinical Medicine at the University Of Naples, a position he held until his death.[1] He was granted Italian citizenship in 1877 and two years later he was appointed Senator.
Cantani conducted medical research on cholera, diabetes, rabies and typhoid fever.[1]
Cantani died from Bright's disease.[2]
Diabetes edit
Cantani treated his diabetic patients by eliminating carbohydrates and prescribing a meat diet.[3] He believed that stopping glycosuria was the major method of controlling diabetes.[4] This became known as Cantani's diet or the "Cantani system".[5]
Cantani allowed his patients as many calories as they could tolerate without glycosuria. Later he limited daily food intake to about one pound of cooked meat. If glucosuria persisted, he fasted his patients.[6] The exclusive meat diet would continue for several months but if urine was not free of sugar it would extend to six or nine months.[3] To control glycosuria, Cantani would enforce his diet restrictions. He would often lock his patients in a room, so they adhered to the strict diet.[7] He performed microscopic studies on the organs from thousands of cases and observed that atrophy and fatty changes were more frequently found in the pancreas of diabetic patients than of non-diabetics.[8][9]
Cantani's exclusive animal food diet consisted of all kinds of meat and animal fats, fish, lobsters and eggs but no dairy as it contains lactose.[10] A list of sanctioned and forbidden foods on Cantani's diet was included in Isaac Burney Yeo's book Food in Health and Disease, published in 1896.[10] Bernhard Naunyn was influenced by the Cantani system.[5]
Cantani also favoured the use of lactic acid to treat diabetes.[11] He administered his patients 77–154 grains of lactic acid daily which was diluted in 8–10 fluid ounces of water. This became known as Cantani's method and influenced George William Balfour.[11]
Selected publications edit
- Patologia e Terapia del Ricambio Materiale (1875)
- Le diabète sucré et son traitement diététique (1876)
References edit
- ^ a b c d e "Arnaldo Cantani, M.D". British Medical Journal. 1 (1690): 1088. 1893. PMC 2403180.
- ^ "Professor Arnoldo Cantini". Medical Record. 43: 691. 1893.
- ^ a b L'Esperance, Francis A; James, William A. (1981). Diabetic Retinopathy: Clinical Evaluation and Management. Mosby. p. 118. ISBN 978-0801629488
- ^ Allen, Frederick M. (1952). "Arnoldo Cantani: Pioneer of Modern Diabetes Treament". Diabetes. 1 (1): 63–65. doi:10.2337/diab.1.1.63. PMID 14906133. S2CID 5332473.
- ^ a b Allen, Frederick M; Stillman, Edgar; Fitz, Reginald (1919). "Total Dietary Regulation in the Treatment of Diabetes" (PDF). Monograph of the Rockefeller Institute for Medical Research. 11: 37.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Davidson, John K. (1991). Clinical Diabetes Mellitus: A Problem Oriented Approach. Thieme. p. 186. ISBN 978-0865773707
- ^ Tobin, Richard B; Mehlman, Myron A. (1980). Advances in Modern Human Nutrition, Volume 1. Pathotox Publishers. p. 137
- ^ Macleod, Archibald Garrard. (1969). Diabetes. Upjohn Company. p. 113
- ^ Lehrer, Steven. (1979). Dramatic Breakthroughs in Medicine from Ancient Times to Modern Science. Doubleday. p. 430
- ^ a b Yeo, Isaac Burney. (1896). Food in Health and Disease. Philadelphia: Lea Brothers. p. 400
- ^ a b Balfour, George William (1871). "On the Treatment of Diabetes by Lactic Acid (Cantani's Method)". Edinburgh Medical Journal. 17 (6): 537. PMC 5402162. PMID 29638424.