Anthocyanidin 3-O-glucosyltransferase

In enzymology, an anthocyanidin 3-O-glucosyltransferase (EC 2.4.1.115) is an enzyme that catalyzes the chemical reaction

anthocyanidin 3-O-glucosyltransferase
Identifiers
EC no.2.4.1.115
CAS no.65607-32-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
UDP-D-glucose + an anthocyanidin UDP + an anthocyanidin-3-O-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-D-glucose and anthocyanidin, whereas its two products are UDP and anthocyanidin-3-O-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase, UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase, UDP-glucose:cyanidin-3-O-glucosyltransferase, UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase, and 3-GT. This enzyme participates in flavonoid biosynthesis.

References

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  • Kamsteeg J, van Brederode J, van Nigtevecht G (1978). "Identification and properties of UDP-glucose: cyanidin-3-O-glucosyltransferase isolated from petals of the red campion (Silene dioica)". Biochem. Genet. 16 (11–12): 1045–58. doi:10.1007/BF00484525. PMID 751640.
  • Ford CM, Boss PK, Hoj PB (1998). "Cloning and characterization of Vitis vinifera UDP-glucose:flavonoid 3-O-glucosyltransferase, a homologue of the enzyme encoded by the maize Bronze-1 locus that may primarily serve to glucosylate anthocyanidins in vivo". J. Biol. Chem. 273 (15): 9224–33. doi:10.1074/jbc.273.15.9224. PMID 9535914.
  • Nakajima J, Tanaka Y, Yamazaki M, Saito K (2001). "Reaction mechanism from leucoanthocyanidin to anthocyanidin 3-glucoside, a key reaction for coloring in anthocyanin biosynthesis". J. Biol. Chem. 276 (28): 25797–803. doi:10.1074/jbc.M100744200. PMID 11316805.