|Anna Komnene Angelina|
|Empress consort of Nicaea|
Theodore I Laskaris
|Father||Alexios III Angelos|
|Mother||Euphrosyne Doukaina Kamatera|
Her first marriage was to the sebastokratōr Isaac Komnenos Vatatzes, a great-nephew of the emperor Manuel I Komnenos. They had one daughter, Theodora Angelina. Soon after Anna's father became emperor, in 1195, Isaac Komnenos was dispatched to combat the Vlach-Bulgarian Rebellion. He was captured, became a pawn between rival Bulgarian and Vlach factions, and died in chains.
Anna and Isaac had one daughter:
- Theodora Angelina, betrothed to Ivanko of Bulgaria, Dobromir Chrysos, and finally Leopold VI, Duke of Austria.
Anna and Theodore had three daughters and two short-lived sons:
- Nicholas Laskaris (died c. 1212)
- John Laskaris (died c. 1212)
- Irene Doukaina Komnene Laskarina, who married first the general Andronikos Palaiologos and then John III Doukas Vatatzes
- Maria Laskarina, who married King Béla IV of Hungary
- Eudokia Laskarina (born between 1210 and 1212, died between 1247 and 1253), engaged to Robert de Courtenay, married firstly and divorced Frederick II, Duke of Austria, secondly (bef. 1230) Anseau de Cayeux, Governor of Asia Minor
- Varzos, Konstantinos (1984). Η Γενεαλογία των Κομνηνών [The Genealogy of the Komnenoi] (PDF) (in Greek). Vol. B. Thessaloniki: Centre for Byzantine Studies, University of Thessaloniki. OCLC 834784665.
- Choniates, Nicetas (1984). O City of Byzantium, Annals of Niketas Choniatēs. Translated by Harry J. Magoulias. Detroit: Wayne State University Press. ISBN 0-8143-1764-2., pages 259, 274, and 280.
- Angold, Michael (2011). "The Latin Empire of Constantinople, 1204–1261: Marriage Strategies". Identities and Allegiances in the Eastern Mediterranean after 1204. Farnham: Ashgate Publishing Limited. pp. 47–68. ISBN 9781409410980.
- Ostrogorsky, George (1956). History of the Byzantine State. Oxford: Basil Blackwell.