Aminobenzoate decarboxylase

The enzyme aminobenzoate decarboxylase (EC 4.1.1.24) catalyzes the chemical reaction

aminobenzoate decarboxylase
Identifiers
EC no.4.1.1.24
CAS no.9024-73-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PubMedarticles
NCBIproteins
4(or 2)-aminobenzoate aniline + CO2

Thus, the two substrates of this enzyme are 4-aminobenzoate and 2-aminobenzoate, whereas its two products are aniline and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is aminobenzoate carboxy-lyase (aniline-forming). It employs one cofactor, pyridoxal phosphate.

References

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  • McCullough WG, Piligian JT, Daniel IJ (1957). "Enzymatic decarboxylation of three aminobenzoates". J. Am. Chem. Soc. 79 (3): 628–630. doi:10.1021/ja01560a032.