Amine sulfotransferase

In enzymology, an amine sulfotransferase (EC 2.8.2.3) is an enzyme that catalyzes the chemical reaction

amine sulfotransferase
Identifiers
EC no.2.8.2.3
CAS no.9026-08-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
3'-phosphoadenylyl sulfate + an amine adenosine 3',5'-bisphosphate + a sulfamate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and amine, whereas its two products are adenosine 3',5'-bisphosphate and sulfamate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:amine N-sulfotransferase. Other names in common use include arylamine sulfotransferase, and amine N-sulfotransferase. This enzyme participates in sulfur metabolism.

References

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  • Ramaswamy SG, Jakoby WB (1987). "Amine N-sulfotransferase". J. Biol. Chem. 262 (21): 10039–43. PMID 3475273.
  • Roy, AB (1960). "The enzymic synthesis of aryl sulphamates". Biochem. J. 74: 49–56.