Alpha-1,4-glucan-protein synthase (ADP-forming)

In enzymology, an alpha-1,4-glucan-protein synthase (ADP-forming) (EC 2.4.1.113) is an enzyme that catalyzes the chemical reaction

alpha-1,4-glucan-protein synthase (ADP-forming)
Identifiers
EC no.2.4.1.113
CAS no.67053-99-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
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NCBIproteins
ADP-glucose + protein ADP + alpha-D-glucosyl-protein

Thus, the two substrates of this enzyme are ADP-glucose and protein, whereas its two products are ADP and alpha-D-glucosyl-protein.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is ADP-glucose:protein 4-alpha-D-glucosyltransferase. Other names in common use include ADP-glucose:protein glucosyltransferase, and adenosine diphosphoglucose-protein glucosyltransferase.

References

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  • Barengo R, Krisman CR (1978). "Initiation of glycogen biosynthesis in Escherichia coli. Studies of the properties of the enzymes involved". Biochim. Biophys. Acta. 540 (2): 190–6. doi:10.1016/0304-4165(78)90131-9. PMID 418819.