Alpha-1,3-glucan synthase

In enzymology, an alpha-1,3-glucan synthase (EC 2.4.1.183) is an enzyme that catalyzes the chemical reaction

alpha-1,3-glucan synthase
Identifiers
EC no.2.4.1.183
CAS no.113478-38-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins
UDP-glucose + [alpha-D-glucosyl-(1-3)]n UDP + [alpha-D-glucosyl-(1-3)]n+1

Thus, the two substrates of this enzyme are UDP-glucose and [[[alpha-D-glucosyl-(1-3)]n]], whereas its two products are UDP and [[[alpha-D-glucosyl-(1-3)]n+1]].

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:alpha-D-(1-3)-glucan 3-alpha-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase, and 1,3-alpha-D-glucan synthase.

References

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  • Andoh M, Yamashita Y, Shigeoka T, Hanada N, Takehara T (1987). "[Extension of the length of glucan chain by 1,3-alpha-D-glucansynthase from Streptococcus mutans serotype.]". Koku Eisei Gakkai Zasshi. 37: 516–517.