6-endo-hydroxycineole dehydrogenase

In enzymology, a 6-endo-hydroxycineole dehydrogenase (EC 1.1.1.241) is an enzyme that catalyzes the chemical reaction

6-endo-hydroxycineole dehydrogenase
Identifiers
EC no.1.1.1.241
CAS no.122933-68-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
6-endo-hydroxycineole + NAD+ 6-oxocineole + NADH + H+

Thus, the two substrates of this enzyme are 6-endo-hydroxycineole and NAD+, whereas its 3 products are 6-oxocineole, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 6-endo-hydroxycineole:NAD+ 6-oxidoreductase. This enzyme participates in terpenoid biosynthesis.

References

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  • Williams DR, Trudgill PW, Taylor DG (1989). "Metabolism of 1,8-cineole by Rhodococcus species: ring cleavage reactions". J. Gen. Microbiol. 135: 1957–1967. doi:10.1099/00221287-135-7-1957.