1721 in literature
This article presents lists of the literary events and publications in 1721.
- John Cleland becomes a pupil at Westminster School, but is soon expelled for an unknown offense.
- Lady Mary Wortley Montagu introduces the Ottoman Turkish method of inoculation against smallpox – variolation – to London. The Princess of Wales is persuaded to test the treatment and it becomes fashionable.
- Thomas Parnell's A Night-Piece on Death is published, inaugurating the "Graveyard poets" movement.
- Joseph Addison – The Works of Joseph Addison
- Penelope Aubin
- The Strange Adventures of the Count de Vinevil and His Family
- The Life of Madam de Beaumont
- Nathan Bailey – An Universal Etymological English Dictionary
- George Berkeley – An Essay Towards Preventing the Ruine of Great Britain
- Richard Blackmore – A New Version of the Psalms of David
- Shaftesbury – Letters from the Late Earl of Shaftesbury, to Robert Molesworth
- Charles Gildon – The Laws of Poetry
- Eliza Haywood – Letters from a Lady of Quality to a Chevalier (translation)
- Montesquieu – Lettres persanes (Persian Letters)
- Alexander Pennecuik – An Ancient Prophecy Concerning Stock-Jobbing, and the Conduct of the Directors of the South-Sea-Company
- Matthew Prior – Colin's Mistakes
- John Sheffield, Duke of Buckingham (died 1721) – The Works of the most noble John Sheffield, late Duke of Buckingham, published by His Grace in his life time
- John Strype – Ecclesiastical Memorials
- Emanuel Swedenborg – Prodromus principiorum rerum naturalium
- Jonathan Swift
- The Bubble
- A Letter to a Young Gentleman, Lately Enter'd into Holy Orders
- Thomas Tickell – Kensington Garden
- Diego de Torres Villarroel – Pronósticos
- Robert Wodrow – The History of the Sufferings of the Church of Scotland
- Colley Cibber – The Refusal
- Eliza Haywood – The Fair Captive
- John Mottley – Antiochus
- Edward Young – The Revenge
- March 19 – Tobias Smollett, Scottish physician and novelist (died 1771)
- August 21 – Lucretia Wilhelmina van Merken, Dutch poet and playwright (died 1789)
- November 9 – Mark Akenside, English poet (died 1770)
- November 16 – Johann Silberschlag, German theologian (died 1791)
- December 25 – William Collins, English poet (died 1759)
- December 27 – François Hemsterhuis, Dutch moral philosopher (died 1790)
- Unknown date – Robert Potter, English translator, poet and cleric (died 1804)
- January 3 – Juan Núñez de la Peña, Spanish historian (born 1641)
- January 26 – Pierre Daniel Huet, French scholar and bishop (born 1630)
- June 18 – Charlwood Lawton, English Jacobite author (born 1660)
- August 13 – Jacques Lelong, French bibliographer (born 1665)
- September 18 – Matthew Prior, English poet and diplomat (born 1664)
- October 14 – Jean Palaprat, French dramatist (born 1650)
- Williams, Hywel (2005). Cassell's Chronology of World History. London: Weidenfeld & Nicolson. ISBN 0-304-35730-8.
- Grundy, Isobel (2004). "Montagu, Lady Mary Wortley". Oxford Dictionary of National Biography. Oxford University Press. Retrieved 2011-09-27. (subscription or UK public library membership required)
- Case, Christine L.; King-Thom, Chung (1997). "Montagu and Jenner: The Campaign Against Smallpox". SIM News. 47 (2): 58–60. Retrieved 2011-09-27.
- Carrell, Jennifer Lee (2003). The Speckled Monster: A Historical Tale of Battling Smallpox. New York: Dutton. ISBN 0-525-94736-1.
- Stoker, David (2004). "Potter, Robert (1721–1804)". Oxford Dictionary of National Biography. Oxford University Press. Retrieved 2010-09-05. (subscription or UK public library membership required)