(+)-neomenthol dehydrogenase

In enzymology, a (+)-neomenthol dehydrogenase (EC 1.1.1.208) is an enzyme that catalyzes the chemical reaction

(+)-neomenthol dehydrogenase
Identifiers
EC no.1.1.1.208
CAS no.81811-47-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
(+)-neomenthol + NADP+ (−)-menthone + NADPH + H+

Thus, the two substrates of this enzyme are (+)-neomenthol and NADP+, whereas its 3 products are (−)-menthone, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-neomenthol:NADP+ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.

References

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  • Kjonaas R, Martinkus-Taylor C, Croteau R (May 1982). "Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves". Plant Physiology. 69 (5): 1013–7. doi:10.1104/pp.69.5.1013. PMC 426349. PMID 16662335.