Zaghloul is a Middle Eastern name, used both as a surname and as a given name.
Notable people with this name as a surname include:
- Ali Faik Zaghloul (1924–1995), Egyptian radio presenter
- Fayez Zaghloul (born 1959), Syrian boxer
- Lutfi Zaghloul (born 1938), Palestinian poet
- Mohamed Zaghloul (born 1993), Egyptian wrestler
- Mona Zaghloul, Egyptian-American electronics engineer
- Saad Zaghloul (1859–1927), Egyptian revolutionary and statesman
- Safiya Zaghloul (1878–1946), Egyptian political activist
Notable people with this name as a given name include:
- Zaghloul El-Naggar (born 1933), Egyptian geologist, Muslim scholar, and author