Wikipedia:Featured article candidates/Myalgic encephalomyelitis/chronic fatigue syndrome/archive1

Myalgic encephalomyelitis/chronic fatigue syndrome

Featured article candidates/Myalgic encephalomyelitis/chronic fatigue syndrome/archive1

Nominator(s): —Femke 🐦 (talk) 10:47, 27 July 2024 (UTC)[reply]

Ten years ago, geneticist Ron Davis called ME/CFS "probably the last major disease that we don't know anything about". A lot has changed since, most notably a global pandemic that led to millions more contracting the illness (15% to 50% of those with long COVID) and the start of research programmes in many countries. A lot still remains to be discovered. ME/CFS has a long and contested history, making it an interesting but difficult article to write. Comments most welcome :).

Many thanks to those helping with pre-FAC reviews, User:Ajpolino, User:Graham Beards, User:RoySmith and User:Draken Bowser, and those involved in the article over the years (User:Innisfree987, User:The Quirky Kitty and User:Ward20). —Femke 🐦 (talk) 10:47, 27 July 2024 (UTC)[reply]

Link to peer review RoySmith (talk) 13:58, 27 July 2024 (UTC)[reply]

Image review

Some images are missing alt text, and some that have it don't have enough description - see MOS:ACCIM. Nikkimaria (talk) 15:02, 27 July 2024 (UTC)[reply]

Added and expanded. —Femke 🐦 (talk) 15:29, 27 July 2024 (UTC)[reply]

Draken Bowser

Back from vacation and ready to review! I like what you did with the prevalence estimate, it seems to reflect the inherent uncertainties while remaining comprehensible.

Classification looks good to me.

Signs and symptoms

or other symptoms - I'd prefer for this to be either more specific or omitted. Could we for example call these "physical symtoms"?
Symptoms significantly reduce the ability to function compared to before the illness started - since this is not about diagnostics could we let this be implicit?

Severity

and 19% have a full-time job - I'm concerned about this for the same reason as the old prevalence estimate.

Causes

but there is not a single gene responsible for increased risk. - is this trying to say that it is likely polygenic or that no candidate genes have been reliably identified?

No suggestions on Pathophysiology or Diagnosis. Time for a break. Draken Bowser (talk) 21:08, 28 July 2024 (UTC)[reply]

Ajpolino

Glad to see this here at last, and looking forward to reviewing in the next few days. Feel free to bother me if I'm not back by midweek. Ajpolino (talk) 23:58, 28 July 2024 (UTC)[reply]

Just getting started, but need to step away for a moment. Enjoying the article so far. Some little things:

Lead - I am uninspired by the first sentence. I assume you wanted to keep it short and sweet, rather than merging it with the second sentence? Anything else we can say here? The word "serious" seems unnecessary since you show us it's serious with your description in the following sentences.
Lead - Similar note for "They are able to do much less than before they became ill." Seems generic; is that not true for many diseases? I think it could be cut, as it's implied much more colorfully by the rest of the paragraph.
Lead - "less than a day to several months." momentarily confusing as it reads like "less than" could also be applied to "several months" (which I suppose it can be). Is "hours to several months" acceptable?
Lead - "avoid flare-ups and counseling..." I've never had the strongest grasp of English grammar, but Sammi Brie has instructed me that a comma belongs here (her essay on the topic in case it's helpful). Ditto "healthcare settings and care is complicated".
Lead - "severely affected and unable to leave their bed or home" seems redundant? Sentence means the same with "severely affected and" cut out.
Classification - "classified under other disorders of the nervous system". I don't feel strongly about this, but "other" is not very meaningful unless you look at the ICD-11 to see what it's "other" relative to. Would it be more meaningful to the reader to skip a level and just say "classified under diseases of the nervous system"?
Classification - "The cause of the illness is unknown and the classification is based on symptoms which indicate a central role of the nervous system." (1) another spot for the Sammi Brie comma. (2) I had to read this twice to understand. I'd suggest cutting the first clause (we know the cause is unknown because you told us four paragraphs earlier) and maybe tweaking to something like "ME/CFS is classified as a neurological disease as many of its symptoms indicate a central role of the nervous system."
Classification - "may better fit" reads as editorializing (I know it's the source's wording, but it's a short "Perspective" piece from an immunologist. A perspective piece is a good place for her to editorialize; the wording fits less well in an encyclopedia article). Is it fair to replace with "is sometimes labelled a neuroimmune condition"?
Signs & symptoms - "The illness..." I assume you're trying to limit the number of sentences starting with "ME/CFS..." but since the prior paragraph described several illnesses, I think this is a time to specify the subject of your sentence clearly.

Will get back to this ASAP. Ajpolino (talk) 20:15, 30 July 2024 (UTC)[reply]

Sgubaldo

Putting my name down; should be able to look at it properly within the next couple days. Sgubaldo (talk) 10:13, 29 July 2024 (UTC)[reply]