WD repeat-containing protein 77

Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene.[5][6][7]

WDR77
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesWDR77, MEP-50, MEP50, Nbla10071, p44, p44/Mep50, HKMT1069, WD repeat domain 77
External IDsOMIM: 611734; MGI: 1917715; HomoloGene: 11466; GeneCards: WDR77; OMA:WDR77 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024102
NM_001317062
NM_001317063
NM_001317064

NM_027432

RefSeq (protein)

NP_001303991
NP_001303992
NP_001303993
NP_077007

NP_081708

Location (UCSC)Chr 1: 111.44 – 111.45 MbChr 3: 105.87 – 105.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

edit

WD repeat-containing protein 77 has been shown to interact with CTDP1[8] and Protein arginine methyltransferase 5.[5]

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116455Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000561Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Friesen WJ, Wyce A, Paushkin S, Abel L, Rappsilber J, Mann M, Dreyfuss G (Mar 2002). "A novel WD repeat protein component of the methylosome binds Sm proteins". J Biol Chem. 277 (10): 8243–7. doi:10.1074/jbc.M109984200. PMID 11756452.
  6. ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  7. ^ "Entrez Gene: WDR77 WD repeat domain 77".
  8. ^ Licciardo P, Amente Stefano, Ruggiero Luca, Monti Maria, Pucci Piero, Lania Luigi, Majello Barbara (Feb 2003). "The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP". Nucleic Acids Res. 31 (3). England: 999–1005. doi:10.1093/nar/gkg197. PMC 149217. PMID 12560496.

Further reading

edit
edit
  • Overview of all the structural information available in the PDB for UniProt: Q9BQA1 (Methylosome protein 50) at the PDBe-KB.