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Tobias1984/Testcase table
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User:Tobias1984
Test case: No data
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Tobias1984/Testcase table
Tobias1984/Testcase table
Test case 1
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Side by side comparison
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Tobias1984/Testcase table
Clinical data
Trade names
Linospan, Zyvox, Zyvoxam, Zyvoxid
AHFS
/
Drugs.com
Monograph
MedlinePlus
a602004
License data
US
FDA
:
Linezolid
Pregnancy
category
C
(
Au
)
, C
(
U.S.
)
Routes of
administration
Intravenous infusion
, oral
ATC code
J01XX08
(
WHO
)
Legal status
Legal status
S4
(Au)
, POM
(
UK
)
, ℞-only
(U.S.)
Pharmacokinetic
data
Bioavailability
~100% (oral)
Protein binding
Low (31%)
Metabolism
Hepatic
(50–70%,
CYP
not involved)
Onset of action
1 hr
Elimination
half-life
4.2–5.4 hours (shorter in children)
Excretion
Nonrenal,
renal
, and fecal
Identifiers
IUPAC name
(
S
)-
N
-({3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
CAS Number
165800-03-3
Y
PubChem
CID
441401
DrugBank
DB00601
ChemSpider
390139
Y
UNII
ISQ9I6J12J
KEGG
D00947
Y
ChEMBL
ChEMBL126
Y
NIAID ChemDB
070944
PDB ligand
ZLD (
PDBe
,
RCSB PDB
)
Chemical and physical data
Formula
C
16
H
20
F
N
3
O
4
Molar mass
337.346 g/mol g·mol
−1
3D model (
JSmol
)
Interactive image
SMILES
O=C1O[C@@H](CNC(=O)C)CN1c3cc(F)c(N2CCOCC2)cc3
InChI
InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
Y
Key:TYZROVQLWOKYKF-ZDUSSCGKSA-N
Y
N
Y
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Tobias1984/Testcase table
Clinical data
License data
US
FDA
:
Linezolid
../licence/sandbox
License data
US
FDA
:
Linezolid