PrasannR

Final Presentation about Cardiac Glycosides

https://docs.google.com/presentation/d/19ldMs3f7TwWAenF2FNQwjqjwhlvtaSQ1RuxhitIONRQ/edit?usp=sharing

Peer Review Comments for Me

Juka Kim:

First of all I really like what you did to your userpage! It's really organized and neat.

- I think Cardenolides and bufadienolides in "Cardenolides differ from bufadienolides" can be linked to its own Wikipedia pages.

- "Most directly, cardiac glycosides affect...cells to alter its function." : I think "most directly" sounds a little awkward for substituting it with a different word may be a good idea.

- "Normally, these sodium-potassium pumps pump potassium ions in and sodium ions out." : I think "pumps pump" is kind of redundant here

- "This effect leads initially to bigeminy: regular ectopic beats following each ventricular contraction." : maybe link "bigeminy" here if the word is defined on Wikipedia

- "Additionally, these compounds have been implicated in cell growth and signaling pathways and have been suggested to be classified as steroid hormones in their own right" : I think "in their own right" is unnecessary here

Overall, I think you have already made a great contribution and it looks like you are really comfortable with Wikipedia. I found the plant fact interesting. The links to other wikipedia pages are used efficiently and appropriately. I don't know how to tell if you added a picture or not but if you haven't already it might be worth while to add one because you go in depth about the structure.

Brittney Nchako:

- See separate paper

Final Article Choice: Cardiac Glycoside

Added introduction paragraph to Cardiac Glycoside

"Cardiac glycosides are a class of organic compounds that affect the inotropic and chronotropic activity of the heart by acting on the sodium-potassium ATPase pump. Their beneficial medical uses are as treatments for congestive heart failure and cardiac arrhythmias. Nevertheless, they have a diverse range of biochemical effects regarding cell growth and development and have also been suggested for use in cancer treatment." PrasannR (talk) 21:42, 4 May 2017 (UTC)

Other article candidates

• Matrix metalloproteinase inhibitor
• Anti-sigma factors
• Venom-induced consumption coagulopathy
• White Cross (chemical warfare)

Class Notes

6/8 Class Notes:

• Final article PDF (with highlighting) + reflective essay due by finals week Friday
  • https://ccle.ucla.edu/course/view/17S-CHEM189-1

6/1 Class Notes:

• First draft information: Focus on reducing technical language so make sure to define all terms such that high-school students can understand them
  • Basically add in a few words/phrase to briefly define the term before using it
• Next week: Five-minute oral presentation of topic, can use ppt/prezi, have it be internet-accessible
  • Basically share with classmates whatever content I added to my article

5/25 Class Notes:

• Feedback for first drafts will be received by 6/1
• In-class presentation on 6/8
  • 5 minute presentation on basically on what I added to the cardiac glycoside page+any necessary background
• Final draft due finals week!
• Peer Review focus: Tone, Bias, Relevance, Accuracy, Organization, Possible additional information, Clarity, Depth of topic, Grammar
  • Basically whatever I would like others to say on my page, I should say for others'
  • Can also photocopy peer reviews for peer+Professor

5/18 Class Notes:

• Print out full article for class next week with what I added highlighted (alternately, with what I did not add highlighted if I end up adding a lot)
• Final article in Word should be about 1-2 pages of text (single-spaced)
• Everything should be properly cited (with in-text references)
  • Use about 50:50 primary:secondary sources
  • For medically relevant articles, should cite reviews that are 1-5 years old
• Media Literacy: recognizing fake news, evaluating articles for bias, looking for what's missing/isn't being shown,
  • "Just because you don't believe it doesn't mean it's not true."
  • http://emboj.embopress.org/about#Review_Process
    • Transparent peer review process

5/11 Class Notes:

• For images, make sure to only use public domain free license copyright images
  • Confirm what kind of free license copyright the image has (https://creativecommons.org/licenses/)
  • When uploading images, Free License Attribution-ShareAlike is default
• Add images by insert--media, can change settings of image with Edit mode
  • Check out https://commons.wikimedia.org/wiki/Main_Page as a database of images/diagrams
  • Sidenote: https://en.wikiversity.org/wiki/Wikiversity:Main_Page This seems pretty cool!
• Can also upload an image I make of a compound using Pymol and then add it into the article
  • Can also use "ChemDraw" program to make images (found on Science building computers)
    • Use "ACS Document 1996" file settings and use View--Periodic Table
    • Use Structure--Name to differentiate between L and D amino acids, for example
    • Save as SVG format and reopen to make sure everything's gucci
    • Use this diagram and make through ChemDraw:http://www.nature.com/nrd/journal/v7/n11/fig_tab/nrd2682_F1.html
    • Follow this format: https://commons.wikimedia.org/wiki/Category:Cardiac_glycosides
• If you do a Google search for an image, the default is to assume that the image is copyright unless you know it is public domain/free license
  • This means that you can cite textbooks but cannot use their images (need to change substantial information and make it your own)
  • If make image from Pymol, just include PDB code for reference

5/4 Class Notes:

• May 25: First draft due, so outline will now become live edits on article
  • Also bring hard copies of these to class (mark what I changed) so that Prof. +2 peers can review them-->peers will give feedback on my own page

TO-DO: Summarize what changes you want to make to page on article's talk page and request for feedback from other users about posted outline

• Post outline of suggested changes to talk page, 1-3 sentences on what each section would include is pretty good

4/27 Class Notes:

• Generally use secondary sources like textbooks/review articles and some primary literature

• Helpful reference pages: "WP:REFB" & "WP:CITE"

4/20 Class Notes:

• Consider reading choosing articles guideline on website.
• Generally will be start/stub class article.
• Try multiple different names for the topic, should prolly be something you're interested in in biochem (any protein/metabolite/process)
• Balance interest in the topic with usefulness in the course to maximize efficiency.
• Refrain from really broad topics because the longer the article the less room to expand it
• Stay away from controversial
• Be careful about directly medically relevant article because your article shouldn't be used for medical advice
• Wikipedia:WikiProject Molecular and Cell Biology tagged topics about relevance to MCDB
  • Stub: title+sentence//Start: paragraph//C: barest vestige of an article//B: getting there, on the way//GA: good article//FA: featured article
  • also wiki project on women scientists
• Wikipedia:WikiProject Women scientists
• Category:Biochemistry
• former article suggestions: enzyme catalysis, active site, brown adipose tissue, proton wires, any complex in ETC, any enzyme/metabolite in glycolysis (most C class articles), taste receptors

Brainstorming articles:

• Cecropin
• Ciguatoxin
  • http://www.fao.org/docrep/007/y5486e/y5486e0q.htm
• Anti-sigma factors
• Cardiac glycoside
• Tetrodotoxin
• Hypokalemic acidosis
• Affibody molecule
• White Cross (chemical warfare)
• Venom-induced consumption coagulopathy
• categories: Category:Top-importance and Start-Class MCB articles