User:Mr. Ibrahem/Silver diammine fluoride

Mr. Ibrahem/Silver diammine fluoride
	Before (left) and after (right) use of SDF in people with tooth decay
Clinical data
Trade names	Fagamin, Advantage Arrest, others
Other names	Diammine silver fluoride, diamine silver fluoride, silver fluoride, silver ammonium fluoride
Legal status
Legal status	US: ℞-only and 510(k) cleared class II medical device;
Identifiers
	IUPAC name Diamminesilver(I) fluoride;
Chemical and physical data
Formula	AgFH6N2
Molar mass	160.929 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES F[Ag]([NH3])[NH3];
	InChI InChI=InChI=1S/Ag.FH.2H3N/h;1H;2*1H3/q+1;;;/p-1;

Silver diammine fluoride (SDF), also spelled silver diamine fluoride, is a medication used to treat and prevent tooth decay and treat sensitive teeth.^[1] It is also useful to identify tooth decay.^[1] It is applied to the teeth.^[1] It appears more effective than fluoride varnish.^[2]

Side effects include permanent staining of cavities black and a metallic taste.^[1] While staining of skin may occur, this is temporary.^[1] When used twice per year in children the risk of dental fluorosis is low.^[1] It contains silver, fluoride, and ammonia ions.^[1] It works by blocking dentin tubules, killing bacteria, and improving remineralization of teeth.^[1]

Silver diammine fluoride was approved for medical use in Japan in the 1960s and the United States in 2014.^[1] It is also available in the United Kingdom and Australia among others.^[1] It is on the World Health Organization's List of Essential Medicines.^[3] In the United States its use costs about 75 USD as of 2021.^[4]

References edit

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Seifo N, Robertson M, MacLean J, Blain K, Grosse S, Milne R, et al. (January 2020). "The use of silver diamine fluoride (SDF) in dental practice". British Dental Journal. 228 (2): 75–81. doi:10.1038/s41415-020-1203-9. PMID 31980777. S2CID 210880141. Archived from the original on 2022-11-01. Retrieved 2022-10-31.
^ Rosenblatt A, Stamford TC, Niederman R (February 2009). "Silver diamine fluoride: a caries "silver-fluoride bullet"". Journal of Dental Research. 88 (2): 116–25. doi:10.1177/0022034508329406. PMID 19278981. S2CID 30730306.
^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
^ Contributors, WebMD Editorial. "What to Know About Silver Diamine Fluoride (SDF) for Dental Care". WebMD. Archived from the original on 31 October 2022. Retrieved 2 December 2022. {{cite web}}: |last1= has generic name (help)

[Sei2020-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l Seifo N, Robertson M, MacLean J, Blain K, Grosse S, Milne R, et al. (January 2020). "The use of silver diamine fluoride (SDF) in dental practice". British Dental Journal. 228 (2): 75–81. doi:10.1038/s41415-020-1203-9. PMID 31980777. S2CID 210880141. Archived from the original on 2022-11-01. Retrieved 2022-10-31.

[Ros2009-2] Rosenblatt A, Stamford TC, Niederman R (February 2009). "Silver diamine fluoride: a caries "silver-fluoride bullet"". Journal of Dental Research. 88 (2): 116–25. doi:10.1177/0022034508329406. PMID 19278981. S2CID 30730306.

[WHO22nd-3] World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.

[4] Contributors, WebMD Editorial. "What to Know About Silver Diamine Fluoride (SDF) for Dental Care". WebMD. Archived from the original on 31 October 2022. Retrieved 2 December 2022. {{cite web}}: |last1= has generic name (help)

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