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User:Mr. Ibrahem/Riboflavin

< User:Mr. Ibrahem
Mr. Ibrahem/Riboflavin
Chemical structure
Clinical data
Trade namesmany
Other namesvactochrome, lactoflavin, vitamin G[1]
AHFS/Drugs.comMonograph
License data
Routes of
administration		by mouth, IM, IV
Legal status
Legal status
Pharmacokinetic data
Elimination half-life66 to 84 minutes
ExcretionUrine
Identifiers
  • 7,8-Dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione
Chemical and physical data
FormulaC17H20N4O6
Molar mass376.369 g·mol−1
3D model (JSmol)
  • c12cc(C)c(C)cc1N=C3C(=O)NC(=O)N=C3N2C[C@H](O)[C@H](O)[C@H](O)CO
  • InChI=InChI=1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1 ☒N
  • Key:AUNGANRZJHBGPY-SCRDCRAPSA-N

Riboflavin, also known as vitamin B2, is a vitamin found in food and used as a dietary supplement.[2][4] Food sources include eggs, green vegetables, milk and other dairy product, meat, mushrooms, and almonds.[4] Some countries require its addition to grains.[4][5] As a supplement it is used to prevent and treat riboflavin deficiency and prevent migraines.[2][4] It may be given by mouth or injection.[2]

It is nearly always well tolerated.[2] Normal doses are safe during pregnancy.[2] Riboflavin is in the vitamin B group.[2] It is required by the body for cellular respiration.[2]

Riboflavin was discovered in 1920, isolated in 1933, and first made in 1935.[6] It is on the World Health Organization's List of Essential Medicines.[7] Riboflavin is available as a generic medication and over the counter.[8] In the United States a month of supplements was priced (in 2015) at less than 25 USD.[8]

References

edit
  1. ^ Cite error: The named reference anm was invoked but never defined (see the help page).
  2. ^ a b c d e f g h "Riboflavin". Drugs.com, The American Society of Health-System Pharmacists. 1 August 2018. Archived from the original on 30 December 2016. Retrieved 7 November 2018.
  3. ^ "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 13 June 2020. Retrieved 15 September 2020.
  4. ^ a b c d "Riboflavin: Fact Sheet for Health Professionals". Office of Dietary Supplements, US National Institutes of Health. 20 August 2018. Archived from the original on 24 February 2020. Retrieved 7 November 2018.
  5. ^ "Why fortify?". Food Fortification Initiative. 2017. Archived from the original on 4 April 2017. Retrieved 4 April 2017.
  6. ^ Squires, Victor R. (2011). The Role of Food, Agriculture, Forestry and Fisheries in Human Nutrition – Volume IV. EOLSS Publications. p. 121. ISBN 9781848261952. Archived from the original on 25 December 2020. Retrieved 8 February 2019.
  7. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  8. ^ a b Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 230. ISBN 9781284057560.
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