User:Mr. Ibrahem/Cyclopentolate

Mr. Ibrahem/Cyclopentolate
Clinical data
Other namesCyclopentolate hydrochloride
AHFS/Drugs.comMonograph
Pregnancy
category
  • C
Drug classMuscarinic antagonist[1]
Identifiers
  • (RS)-2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate
Chemical and physical data
FormulaC17H25NO3
Molar mass291.391 g·mol−1
3D model (JSmol)
  • O=C(OCCN(C)C)C(c1ccccc1)C2(O)CCCC2
  • InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3 checkY
  • Key:SKYSRIRYMSLOIN-UHFFFAOYSA-N checkY

Cyclopentolate is a medication used to dilate the eyes to help with eye examination.[1] It may also be used to help with the pain of uveitis (iritis).[2] It is applied as an eye drop.[2] Maximal effect occurs within an hour and usually lasts about a day.[1]

Common side effects include increased eye pressure, eye irritation, blurry vision, and sensitivity to light.[1] Other side effects may include behavioral changes and allergic reactions.[1] Safety in pregnancy is unclear.[1] It is a muscarinic antagonist.[1]

Cyclopentolate was approved for medical use in the United States in 1974.[1] It is available as a generic medication.[3] It is on the World Health Organization's List of Essential Medicines as an alternative to tropicamide.[4] In the United Kingdom 10 ml (20 doses) costs the NHS about £11 as of 2021.[2] This amount in the United States is about 18 USD.[3]

References

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  1. ^ a b c d e f g h i j "Cyclopentolate Monograph for Professionals". Drugs.com. Archived from the original on 29 September 2021. Retrieved 7 January 2022.
  2. ^ a b c d BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1222. ISBN 978-0857114105.
  3. ^ a b "Cyclopentolate Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 7 January 2022.
  4. ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.